ID A0A0B0ER45_9BACT Unreviewed; 1098 AA.
AC A0A0B0ER45;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=type I site-specific deoxyribonuclease {ECO:0000256|ARBA:ARBA00012654};
DE EC=3.1.21.3 {ECO:0000256|ARBA:ARBA00012654};
GN ORFNames=SCABRO_00663 {ECO:0000313|EMBL:KHE93618.1};
OS Candidatus Scalindua brodae.
OC Bacteria; Planctomycetota; Candidatus Brocadiia; Candidatus Brocadiales;
OC Candidatus Scalinduaceae; Scalindua.
OX NCBI_TaxID=237368 {ECO:0000313|EMBL:KHE93618.1, ECO:0000313|Proteomes:UP000030652};
RN [1] {ECO:0000313|EMBL:KHE93618.1, ECO:0000313|Proteomes:UP000030652}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RU1 {ECO:0000313|EMBL:KHE93618.1};
RA Speth D.R., Russ L., Kartal B., Op den Camp H.J., Dutilh B.E., Jetten M.S.;
RT "Draft genome of anammox bacterium scalindua brodae, obtained using
RT differential coverage binning of sequence data from two enrichment
RT reactors.";
RL Submitted (OCT-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Endonucleolytic cleavage of DNA to give random double-stranded
CC fragments with terminal 5'-phosphates, ATP is simultaneously
CC hydrolyzed.; EC=3.1.21.3; Evidence={ECO:0000256|ARBA:ARBA00000851};
CC -!- SIMILARITY: Belongs to the HsdR family.
CC {ECO:0000256|ARBA:ARBA00008598}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KHE93618.1}.
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DR EMBL; JRYO01000046; KHE93618.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0B0ER45; -.
DR REBASE; 103245; SbrRU1ORF665P.
DR PATRIC; fig|237368.3.peg.719; -.
DR eggNOG; COG0610; Bacteria.
DR Proteomes; UP000030652; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0009035; F:type I site-specific deoxyribonuclease activity; IEA:UniProtKB-EC.
DR GO; GO:0009307; P:DNA restriction-modification system; IEA:UniProtKB-KW.
DR Gene3D; 3.90.1570.50; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR007409; Restrct_endonuc_type1_HsdR_N.
DR InterPro; IPR040980; SWI2_SNF2.
DR PANTHER; PTHR42927; HELICASE SUPERFAMILY 1 AND 2 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR42927:SF1; HELICASE SUPERFAMILY 1 AND 2 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF04313; HSDR_N; 1.
DR Pfam; PF18766; SWI2_SNF2; 1.
DR SMART; SM00487; DEXDc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Endonuclease {ECO:0000256|ARBA:ARBA00022759};
KW Helicase {ECO:0000313|EMBL:KHE93618.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Restriction system {ECO:0000256|ARBA:ARBA00022747}.
FT DOMAIN 338..541
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
SQ SEQUENCE 1098 AA; 125223 MW; FA04B47F9F6366E2 CRC64;
MNDKSIESVF QNEMINQMVA NGWLLGKPEN YNRDLALYEE DLLGFIKETQ DGQWQKFCKL
YPNNPEQKFL ERVASQLNKA DPNAANKEMR TFGTLGVLRH ELRDRGTRFT LCQFKPEHDL
NPDTLARYEK NRLRIVPELV YSPWADISTL SQPSPKGEGD EHLAQAGAKA KAWRIDLVLF
VNGLPIATLE LKSEFKQAVY NAIKQYKTTR FPIDPATKKP EPLLTFKRGA LVHFAVSQYE
VFMTTHLKGE ETFFLPFNKG TEEGGAGNDT PKDVNRYATD YLWNDVLLPD NLLNILARYV
HLQIEEKEDW EGRKFKVETM IFPRYHQWDV VNRLIDAART EGPGHKYLIQ HSAGSGKSNS
IAWTAHQLSS LYNQAGNKQF DSVIIVTDRN VLDAQLQDTI YQFEHMDGVV GRINKEEGDG
SKSEKLASAL ESSQPIIIVT IQTFPFVLKA IENSVSLKER NYAIIADEAH SSQTGSTARQ
LKEVLMIEGS DEEELTADDI LDAAVASRRT SNNLSYFAFT ATPKTKTLEL FGRLPNPDEP
PSKTNLPKSY HVYSMRQAIE EGFILDVLKN YTNYKVAYNL ALAIQSKDQE VESKKAKVKL
NQWVRLHDYN ISQKVQVIIE HFRDNVMGLL GGQAKAMVVT SSRKEAVRYK LCFDKYITEK
GYQTIHAMVA FSGEVEFNEN DPNTEGLIGE KFTENNMNPN LKGRDMRKAF ESKDYQVMIV
ANKFQTGFDQ PKLCAMYVDK KLGGVECVQT LSRLNRIYPG KSDSGTFILD FFNEPEDILE
SFKPYYQTAE LADVSDPDLI FNLFDKLRAA GIFLWSEVEQ FCEAFFKKSK SNAAIANICK
PAVERWKIRY KSAVEAYKQA KEIFDRTKKS TDPVLIANAE NSLKECKREK DALDIFKKDL
GTFVRFYEFM SQIVDYNDKD LEKLSLYSRN LRPMLRESLI DEDDIDLQSV ELSHYRLTAI
RQQENLGISD SKDSTDEYKL MPGEGLGTAK AKDKKEELIS QVISRLNELF ITDQLTDNDL
VNYAYTIRDK VKEDELVMKQ IANNTSEQAM LGDFHKAVDN AVIDSSEAHQ NQMMQLLSDP
KKSAGFARVV FDLLKLAS
//
