ID A0A0B0H6U3_SOVGS Unreviewed; 1367 AA.
AC A0A0B0H6U3;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Multidrug efflux pump AcrAB, subunit B3 {ECO:0000313|EMBL:KHF24825.1};
GN Name=acrB3 {ECO:0000313|EMBL:KHF24825.1};
GN ORFNames=JV46_03460 {ECO:0000313|EMBL:KHF24825.1};
OS Solemya velum gill symbiont.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; sulfur-oxidizing symbionts.
OX NCBI_TaxID=2340 {ECO:0000313|EMBL:KHF24825.1, ECO:0000313|Proteomes:UP000030856};
RN [1] {ECO:0000313|EMBL:KHF24825.1, ECO:0000313|Proteomes:UP000030856}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WH {ECO:0000313|EMBL:KHF24825.1,
RC ECO:0000313|Proteomes:UP000030856};
RX PubMed=25342549; DOI=10.1186/1471-2164-15-924;
RA Dmytrenko O., Russell S.L., Loo W.T., Fontanez K.M., Liao L., Roeselers G.,
RA Sharma R., Stewart F.J., Newton I.L., Woyke T., Wu D., Lang J.M.,
RA Eisen J.A., Cavanaugh C.M.;
RT "The genome of the intracellular bacterium of the coastal bivalve, Solemya
RT velum: a blueprint for thriving in and out of symbiosis.";
RL BMC Genomics 15:924-924(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KHF24825.1}.
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DR EMBL; JRAA01000002; KHF24825.1; -; Genomic_DNA.
DR RefSeq; WP_043117047.1; NZ_JRAA01000002.1.
DR STRING; 2340.JV46_03460; -.
DR PATRIC; fig|2340.3.peg.1461; -.
DR eggNOG; COG0841; Bacteria.
DR OrthoDB; 9758297at2; -.
DR Proteomes; UP000030856; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR027463; AcrB_DN_DC_subdom.
DR InterPro; IPR001036; Acrflvin-R.
DR PANTHER; PTHR32063; -; 1.
DR PANTHER; PTHR32063:SF16; CATION EFFLUX SYSTEM (ACRB_ACRD_ACRF FAMILY); 1.
DR Pfam; PF00873; ACR_tran; 2.
DR PRINTS; PR00702; ACRIFLAVINRP.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000030856};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 35..51
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 373..392
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 399..420
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 426..450
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 471..491
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 503..527
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 576..594
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 940..957
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 964..984
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 996..1017
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1038..1057
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1063..1085
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1133..1155
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1164..1367
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1164..1204
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1263..1279
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1351..1367
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1367 AA; 148208 MW; 61A8166C526BF1B6 CRC64;
MSQRVDNNLD ELKDKDLGIA GNTARAFINS PLSPLLYAAM LLMGIMGYLL IPRQEDPQIS
VPMVDLIVPY PGASAEQVSV RAIEPLERMM SEIKGVKHVY SASQRGMGMV TVQFEVGEEM
NDSLVKVNDK IDSNMDKIPS GVSPPMVSPV GIDDVPVVTL TLWSKDLNQD NHPDVDDSQL
RMLAHDILQN LNELPNTSEG FVVGGRKEVV KVEVLPEILA GYGISIGQVA QAIQTANQET
QAGSVESGGT HLTVVTGKFL KHARDVSELI VGTFGGAPIH LRDVAVVTQG PEDASKLVAF
YSGPQSPESI GRVDGSPAVT IAIAKQEGTN GVTVANAVLE RVEELKGRVI PTNVDVFVTR
NYGQTANDKV NELIFKLFVA TSIVFALVLV AFRAFKPALV VTLVIPVVLL MTIFVAWLLG
FTIDRVSLFA LIFSIGILVD DAIVVIENIY RRWLQNDSTD MATAVDAVRE VGNPTILATF
TVIGALLPMG FVSGMMGPYM FPIPALGSVA MLISLFAAFV FTPWLAISGL FRPSMNYLAA
AEEREHKEAE RLEGMFRRIL MPMIDKPAKR KMFNGILWLL LIFACSFFYF KWVAVKMLPL
DNKPEFSVVI DMPEGTALPD TANLTASMAE KLRQFPEVTA IQTYVGTARP FDFNGMVRHY
YTRRQPWQAD IQVQLLDKND RERTSHEIAV EARRILREMI KGTRTRIAVV EMPPGPPVLQ
SVVAEVHGPD DKSRREVARH LTRLFEEAPN LTDVDNYMRE PYSYWRFEAD REKASRAGVN
QESINQNIAM ALGSAPMGDV KNLAGHEPIN IVLQVPFAER SQVTRLGDLP VNTATGEVVS
LREFGQFVRM EEDEIIYHKD LRSVEYVVAD VSGRLAAPVY GMMQVQDALA AANDGQGYVA
PDGAILGNNI EWMGPPANDI ESSFEWTGEW TVTYETFRDM GAAFMVALAV IYFLVVIEFG
NFRIPAVIMA PIPLTLLGII PAHAFVGAEF TATSMIGWIA LAGIIVRNSI LLVDFTIHEV
RAGVVLEEAV IKACMTRTRP IVITALALVG GSAVILTDPI FQGMAISLAA GVLVSTVLTL
IVIPLGTTKA AKALYQVAGV DMPDGSGGTT STPAPAAAPV APKRSFTDMA FMVWGKLIGA
IFALISFFGI LMNWLRLLLP KKKPPQAPPP AAPQPPAAPK PPPTPPPVPE AAPVPEPAPE
PEPQAPAAEA EQKFVAEPEP VAETPKPVVE APAPEPVAEA PISEPEIEAP APEVVEPIVA
EPVTAPEPKP EPEPEVVAPE PAAPVVEQRK VAEPLQADED IIEVSQASDD DIDLLSAPIR
PTSVAAAKSD SASQMPGATV PQPGKRRRRG IRLRDMPDES DDQGGKE
//
