ID A0A0B0H7C2_SOVGS Unreviewed; 1236 AA.
AC A0A0B0H7C2;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Ribonuclease HI {ECO:0000313|EMBL:KHF24557.1};
GN ORFNames=JV46_28950 {ECO:0000313|EMBL:KHF24557.1};
OS Solemya velum gill symbiont.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; sulfur-oxidizing symbionts.
OX NCBI_TaxID=2340 {ECO:0000313|EMBL:KHF24557.1, ECO:0000313|Proteomes:UP000030856};
RN [1] {ECO:0000313|EMBL:KHF24557.1, ECO:0000313|Proteomes:UP000030856}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WH {ECO:0000313|EMBL:KHF24557.1,
RC ECO:0000313|Proteomes:UP000030856};
RX PubMed=25342549; DOI=10.1186/1471-2164-15-924;
RA Dmytrenko O., Russell S.L., Loo W.T., Fontanez K.M., Liao L., Roeselers G.,
RA Sharma R., Stewart F.J., Newton I.L., Woyke T., Wu D., Lang J.M.,
RA Eisen J.A., Cavanaugh C.M.;
RT "The genome of the intracellular bacterium of the coastal bivalve, Solemya
RT velum: a blueprint for thriving in and out of symbiosis.";
RL BMC Genomics 15:924-924(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KHF24557.1}.
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DR EMBL; JRAA01000003; KHF24557.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0B0H7C2; -.
DR STRING; 2340.JV46_28950; -.
DR eggNOG; ENOG503488J; Bacteria.
DR OrthoDB; 7069107at2; -.
DR Proteomes; UP000030856; Unassembled WGS sequence.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR CDD; cd09276; Rnase_HI_RT_non_LTR; 1.
DR CDD; cd01650; RT_nLTR_like; 1.
DR Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR InterPro; IPR005135; Endo/exonuclease/phosphatase.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR002156; RNaseH_domain.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR000477; RT_dom.
DR PANTHER; PTHR36688; ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR36688:SF1; ENDO_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF14529; Exo_endo_phos_2; 1.
DR Pfam; PF00075; RNase_H; 1.
DR Pfam; PF00078; RVT_1; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF56219; DNase I-like; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50879; RNASE_H_1; 1.
DR PROSITE; PS50878; RT_POL; 1.
PE 4: Predicted;
KW Endonuclease {ECO:0000256|ARBA:ARBA00022759};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022759};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Reference proteome {ECO:0000313|Proteomes:UP000030856}.
FT DOMAIN 485..756
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
FT DOMAIN 967..1094
FT /note="RNase H type-1"
FT /evidence="ECO:0000259|PROSITE:PS50879"
SQ SEQUENCE 1236 AA; 140876 MW; 5387B13783EAD484 CRC64;
MYNILSIIFI IFLSFSIMAT HNILQWNCRG FRANYEELGL LVQKYNPKVI CLQETFLPLN
SSFRLKNYTA YHDASTSIFI HSTVHHTPIS LNTPLSVTAV RVTLHKVITI CSVYLPPKQQ
FQLSDLDTLF LQLPSPQLLL GDFNGANQLW GSASNNPRGD LIENFLTINN LCLFNDKSPT
FLHSGHGTFS SIDLSISDPS LFLDFEWSVE NDLHGSDHFP LILKNTELEN TAHPPKWKMS
KANWTQFESL CLEKLTKTSV NSTTIDDYTS ILLTIADDSI PKTSGKSIAR RNPWFNDDCK
EAIAKRKRDL RHFKQEPTSA NLGAFKISRA QARRTVRQTR KNSWRDYVSR LNNRTSPKSV
WRTIRSMNGK GGGSKGAPTH LSEQNTPITD KLHIANTLGD KFSQNSSSSN CSDAFSAHRA
KLEQHPLNFK SSNFEDYNTV FSLNELQISL SKSHNSAPGP DGIHYELLKH LPSQSLELLL
DIFNYIWTSG SLPSSWKEAT VIPITKPGKD STDPANYRPI SLTSCLCKTM ERMINDRLVW
FLESNNLLTN LQCGFRQGRS TIDHLVRLES YIRDAFLKKE HVVTVFFDLE KAYETTWQYG
ILKDLFDFGL KGRLPVFIQN FLNDRHFRVR LGSTLSDTFS QEMGVPQGSI LSVTLFSIKI
NSIVSCMKTD TEGSLYVDDF SISYRSKHMC TMERHLQQCL NKLDEWANTN GFKFSKTKTV
CMHFCQLRGL HPDPTLLLAK APIPVVKEFK FLGLLLDPKL TFIPHIRYLR VKCRKSLDIL
KVLSSTDWGS DRDTLLMLYK SVILSKLDYA SIIYGSARPS YLRPLDSIHH QGLRLCLGAY
RTSPVESLYV ESNVPSLSLR RTKLSLDYAT KMTAYPSNPA YDCVFHAQHE NLYEQHQRFI
PSFGIRTIPN FEAAEIPSTD ILLNKLSSKP PWSLKIPSIL YTMHNKSKST THPLAFQSLF
AEIRHTYSTH QPIYTDGSKD QEKVSAAMYA PPSVDTARLP NNSSIFSAEL YALLLALQSI
QSHKASKFIV FTDSLSSLQS LSSFKITHPL VLQLLEFYNL LLQKGKTIVF CWIPSHMGIR
GNEKVDSIAK TALNSDMSSF KVPYSDFKPL SRKYINYFWQ LEWDTLDGNK LHRIQSSLKQ
NKHHPGLGRR DNVVLTRLRI GHSHITHSYL LKKEPRPVCD VCDVPLTVEH FLLTCSVFTS
SRLSFFNVTS LKMLFETVAP EHILSYLRSI NFYRKI
//
