ID   A0A0B0KIE6_9GAMM        Unreviewed;      1017 AA.
AC   A0A0B0KIE6;
DT   04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT   04-MAR-2015, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=site-specific DNA-methyltransferase (adenine-specific) {ECO:0000256|ARBA:ARBA00011900};
DE            EC=2.1.1.72 {ECO:0000256|ARBA:ARBA00011900};
GN   ORFNames=PJ15_3523 {ECO:0000313|EMBL:KHF77247.1};
OS   Acinetobacter sp. neg1.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC   Acinetobacter.
OX   NCBI_TaxID=1561068 {ECO:0000313|EMBL:KHF77247.1, ECO:0000313|Proteomes:UP000030886};
RN   [1] {ECO:0000313|EMBL:KHF77247.1, ECO:0000313|Proteomes:UP000030886}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=neg1 {ECO:0000313|Proteomes:UP000030886};
RA   Chiara M., Horner D.S., Pesole G., Mule' G., Logrieco A., Fanelli F.;
RT   "Genome Sequencing of an Acinetobacter spp capable to degrade OTA.";
RL   Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an
CC         N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-
CC         homocysteine; Xref=Rhea:RHEA:15197, Rhea:RHEA-COMP:12418, Rhea:RHEA-
CC         COMP:12419, ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC         ChEBI:CHEBI:90615, ChEBI:CHEBI:90616; EC=2.1.1.72;
CC         Evidence={ECO:0000256|ARBA:ARBA00001279};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KHF77247.1}.
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DR   EMBL; JSZD01000012; KHF77247.1; -; Genomic_DNA.
DR   RefSeq; WP_047430147.1; NZ_JSZD01000012.1.
DR   AlphaFoldDB; A0A0B0KIE6; -.
DR   PATRIC; fig|1561068.3.peg.1821; -.
DR   Proteomes; UP000030886; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0008170; F:N-methyltransferase activity; IEA:InterPro.
DR   GO; GO:0009007; F:site-specific DNA-methyltransferase (adenine-specific) activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR003356; DNA_methylase_A-5.
DR   InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR33841:SF1; ADENINE-SPECIFIC METHYLTRANSFERASE PGLX; 1.
DR   PANTHER; PTHR33841; DNA METHYLTRANSFERASE YEEA-RELATED; 1.
DR   Pfam; PF02384; N6_Mtase; 1.
DR   PRINTS; PR00507; N12N6MTFRASE.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR   PROSITE; PS00092; N6_MTASE; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          299..565
FT                   /note="DNA methylase adenine-specific"
FT                   /evidence="ECO:0000259|Pfam:PF02384"
SQ   SEQUENCE   1017 AA;  116831 MW;  C801B622F55F21A1 CRC64;
     MDDSMKHSLL QDPTKYGISE NMLIQFSEKE PLYVHLSYLD LFTNEIDKRP DAVVEINGRA
     ALYLVSENIF TIDELRQLKE ILASRADARF LGVLRAGVID IYPLGIFSEN DDQPIVKRID
     LSESSINLHD FLIGNLTDKL DKKNNQRKVE QSWLENYLFR LLQTTARNLR ENICANKLTD
     NQILSLVGRA LFTRFLIDRK IIVDSDVGNI SNKTSKLNNL FNSVSSISDT FAWLDKTFNG
     NLLPLGNFYY NSEDYKEFFS QIGDESEHIC FELQDILLAT INRQMSLDWG RIQFQHVPAD
     MLSQVYEHFA HAYQNEFARK TSIHYTPSHI AKILVDSAFD GLEIEDKSSA QILDPSAGAG
     VFLVLAFKRL VLEKWKITGE RPTRNQIRGI LNRQLVGLDI NSESLKFAAL SLYLTALELD
     PNPTPLSELK FDCLNTKTLI NVSFGEDLQE TLGSLSERLP VELNERFDIV VGNPPWTKQR
     GRGVGEKFNE LIERIAISRG IDSKIASQFN VGCDPDIPFI WRAIEWCKPN GMIAYALHAQ
     HTLFNYGNSF ILRSALFDCI ELTGIFNGSA LRQEKAIWEN NDAPFCFLIA KNRKPSPFSS
     FYYLSPYVEK SLNEQGGFRM DPHMAIPVEQ SQVQANPHLL KTLFRGSWLD HEIIEKIRTN
     SEVITLQEFC DKWKLICGSG FQLGSQKVDA SLFKGKYLFD SKEKNKHQYI INTSRLHYFY
     HDRIYGNRNP QLFKAPLVLF LESPPPFRNQ RGALLSTEEV IYSESYVGVS TAKHSSPILL
     AKYLQLISYS NLFLYYFLMT SAKFGVERDA ILTKEIFTFP LIDFGSFNEE QLTLIESLSE
     KLINREEPWN EIDQFMASIY GLNKNEMQVI EDSLKMSLPY AENKKVAQNN PENETLECFQ
     NELCRVINPF TKRLNLKLWT SIEDNLNGNQ SGWKFIRIGF SEPKDINNNL SHKFLSELAD
     QFWVSQVKIH IDETGCELLI GQLAQNRYWT KTKARLLALD ILNTDLDRAY NYCEGIQ
//