ID   A0A0B0Q3K9_GOSAR        Unreviewed;       488 AA.
AC   A0A0B0Q3K9;
DT   04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT   04-MAR-2015, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   SubName: Full=Vacuolar-processing enzyme {ECO:0000313|EMBL:KHG30636.1};
GN   ORFNames=F383_15130 {ECO:0000313|EMBL:KHG30636.1};
OS   Gossypium arboreum (Tree cotton) (Gossypium nanking).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX   NCBI_TaxID=29729 {ECO:0000313|EMBL:KHG30636.1, ECO:0000313|Proteomes:UP000032142};
RN   [1] {ECO:0000313|Proteomes:UP000032142}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=cv. AKA8401 {ECO:0000313|Proteomes:UP000032142};
RA   Mudge J., Ramaraj T., Lindquist I.E., Bharti A.K., Sundararajan A.,
RA   Cameron C.T., Woodward J.E., May G.D., Brubaker C., Broadhvest J.,
RA   Wilkins T.A.;
RL   Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase C13 family.
CC       {ECO:0000256|ARBA:ARBA00009941}.
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DR   EMBL; KN458799; KHG30636.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0B0Q3K9; -.
DR   Proteomes; UP000032142; Unassembled WGS sequence.
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0051603; P:proteolysis involved in protein catabolic process; IEA:InterPro.
DR   CDD; cd21115; legumain_C; 1.
DR   Gene3D; 1.10.132.130; -; 1.
DR   Gene3D; 3.40.50.1460; -; 1.
DR   InterPro; IPR043577; AE.
DR   InterPro; IPR048501; Legum_prodom.
DR   InterPro; IPR046427; Legumain_prodom_sf.
DR   InterPro; IPR001096; Peptidase_C13.
DR   PANTHER; PTHR12000; HEMOGLOBINASE FAMILY MEMBER; 1.
DR   PANTHER; PTHR12000:SF42; LEGUMAIN; 1.
DR   Pfam; PF20985; Legum_prodom; 1.
DR   Pfam; PF01650; Peptidase_C13; 1.
DR   PIRSF; PIRSF500139; AE; 1.
DR   PIRSF; PIRSF019663; Legumain; 1.
DR   PRINTS; PR00776; HEMOGLOBNASE.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Protease {ECO:0000256|ARBA:ARBA00022670};
KW   Reference proteome {ECO:0000313|Proteomes:UP000032142};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           22..488
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5002059772"
FT   DOMAIN          375..471
FT                   /note="Legumain prodomain"
FT                   /evidence="ECO:0000259|Pfam:PF20985"
FT   ACT_SITE        171
FT                   /evidence="ECO:0000256|PIRSR:PIRSR019663-1"
FT   ACT_SITE        213
FT                   /note="Nucleophile"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR019663-1"
SQ   SEQUENCE   488 AA;  54014 MW;  9E5659CBA596C17D CRC64;
     MTTLVTGVFL LLLSFAGVVS AARYITGDVL RLPSEASRFF RWRSDDDEVG GTRWAVLIAG
     SNGYWNYRHQ ADVCHAYQLL RNGGLKEENI IVFMYDDIAY NEENPRPGII INNPHGDDVY
     KGVPKDYTGE NVTVNNFFAA ILGNKSALTG GSGKVVNSGP SDHIFIYYSD HGGPGVLGMP
     TLPYLYADDL IDVLKKKHAS GTYKSLVFYL EACESGSIFE GLLPEGLNIY ATTAANAVES
     SWGTYCPGEY PSPPPEYETC LGDLYSVAWM EDSDIHNLRK ETLHQQYELV KRRTINGNSA
     YGSHVMQFGD IGISMDNLFT YLGTNPANDN FKSVDENSLL PPTKAVNQRD ADLVHFWDKY
     RKAPDGSVRK VEAQKQVMEA MSHRMHVDNS IQLIGKLLFG VERGPEVLNT VRPTGQPLVD
     DWKCLKKMVR TFETHCGSLA QYGMKHMRSL ANICNAGIET EKMGEVSAQA CVNIPSGHWG
     SVEKGFSA
//