ID A0A0B1P2N9_UNCNE Unreviewed; 984 AA.
AC A0A0B1P2N9;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 13-SEP-2023, entry version 28.
DE SubName: Full=Putative dna mismatch repair protein {ECO:0000313|EMBL:KHJ32947.1};
GN ORFNames=EV44_g4405 {ECO:0000313|EMBL:KHJ32947.1};
OS Uncinula necator (Grape powdery mildew).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Erysiphales; Erysiphaceae; Erysiphe.
OX NCBI_TaxID=52586 {ECO:0000313|EMBL:KHJ32947.1, ECO:0000313|Proteomes:UP000030854};
RN [1] {ECO:0000313|EMBL:KHJ32947.1, ECO:0000313|Proteomes:UP000030854}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=c {ECO:0000313|Proteomes:UP000030854};
RX PubMed=25487071;
RA Jones L., Riaz S., Morales-Cruz A., Amrine K.C., McGuire B., Gubler W.D.,
RA Walker M.A., Cantu D.;
RT "Adaptive genomic structural variation in the grape powdery mildew
RT pathogen, Erysiphe necator.";
RL BMC Genomics 15:1081-1081(2014).
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutL/HexB family.
CC {ECO:0000256|ARBA:ARBA00006082}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KHJ32947.1}.
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DR EMBL; JNVN01001704; KHJ32947.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0B1P2N9; -.
DR STRING; 52586.A0A0B1P2N9; -.
DR HOGENOM; CLU_005415_0_0_1; -.
DR OMA; NKWPMFY; -.
DR OrthoDB; 9570at2759; -.
DR Proteomes; UP000030854; Unassembled WGS sequence.
DR GO; GO:0032300; C:mismatch repair complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.1540.20; MutL, C-terminal domain, dimerisation subdomain; 1.
DR Gene3D; 3.30.1370.100; MutL, C-terminal domain, regulatory subdomain; 1.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR038973; MutL/Mlh/Pms-like.
DR InterPro; IPR014790; MutL_C.
DR InterPro; IPR042120; MutL_C_dimsub.
DR InterPro; IPR042121; MutL_C_regsub.
DR InterPro; IPR037198; MutL_C_sf.
DR PANTHER; PTHR10073; DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL; 1.
DR PANTHER; PTHR10073:SF47; DNA MISMATCH REPAIR PROTEIN MLH3; 1.
DR Pfam; PF13589; HATPase_c_3; 1.
DR Pfam; PF08676; MutL_C; 1.
DR SMART; SM00853; MutL_C; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF118116; DNA mismatch repair protein MutL; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000030854}.
FT DOMAIN 713..911
FT /note="MutL C-terminal dimerisation"
FT /evidence="ECO:0000259|SMART:SM00853"
FT REGION 574..597
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 984 AA; 112075 MW; D23B310758DD69DF CRC64;
MSIVALPQHV TAQINSSSSF TCLNDVVLAL FKNSLDASCT KIEITVDYSR GLCVVEDNGV
GILPSEFRES GGLGKPYHTS KQYETEVVHG RRGNSLASIS AIAFLTITSH HFLYQSHNTL
CINNSAVLFR QLPALPQHHL LYDHGTRVTI HNLFGNIPVR IKQRVINSRK QGGNGKEWND
LLIGLIRLLF PWTRAQVSVT MRDKITNNKI YLQAPSHKSV KESPIKKFCS ILRQASIITA
EDTRSWIPVQ ASTEGLRIIG AVSLQPYVSK RCQFLSFGIK PIFPEESSLY EDINKLFSNS
SFGNIEVASK IEGQEIKHCK DDKRCKRTDY TSKELKCVKG IEKWPKFYLN ILPEVTVEKS
LSDYADCNFW TKLESYSMKV RELLQELIWK FLSDNSFLPR PICQKRFKKD GLISIPAVES
LPQSMIMNST QNHPLSSTSS LAQRKKIIHN EFGMDIKLPS FRQNVLSLEL SNDITSKIKR
GKLTRASSIS MLNNESKLDD QEFTERSFSL PLKVTNVLEP RVCERQIFKV SEKKIFSMSA
KPLTCELIKD SEVPEKCSCN FLSKNDSDFT PSFQPSEIHR PIAPKDTISS RSNSMTHNQH
NFGQRIDFLV APQTFQLESS TKRFFRQKIC TKMTPNDPNS WMSQCLRSWN NPVYVPAEKP
IPQLSIESQH LKQRFSAGQF QNYIQADANH RPDMKGARLN NRISKRALKD AKFISQVDNK
FIFVKVFTTD CKELAQRSED LLVMIDQHAA DERIRIESLL EELCTPAMIT EVDSPYRVKS
YILMRPLIIS LPPNEIELLF TYRNYFLSWG FSYKLPAHGS VSNQTNNNQT LIVLSLPPVI
AERCQQQPHL LSSLLRKEIC KLQDSNDNLQ VLSTFSSSTS WLDRIHTCPV GVLDLLNTRA
CRSAIMFNDE LSEEQCRILV KRLAECSFPF MCAHGRPSMV PLAKLSTLGF NQDSSQIWNS
KGFLPTLSLG AQFKKWKRQR YCGS
//
