ID A0A0B1P7Z8_UNCNE Unreviewed; 1594 AA.
AC A0A0B1P7Z8;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 08-NOV-2023, entry version 33.
DE SubName: Full=Putative gtpase activating protein {ECO:0000313|EMBL:KHJ34373.1};
GN ORFNames=EV44_g4694 {ECO:0000313|EMBL:KHJ34373.1};
OS Uncinula necator (Grape powdery mildew).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Erysiphales; Erysiphaceae; Erysiphe.
OX NCBI_TaxID=52586 {ECO:0000313|EMBL:KHJ34373.1, ECO:0000313|Proteomes:UP000030854};
RN [1] {ECO:0000313|EMBL:KHJ34373.1, ECO:0000313|Proteomes:UP000030854}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=c {ECO:0000313|Proteomes:UP000030854};
RX PubMed=25487071;
RA Jones L., Riaz S., Morales-Cruz A., Amrine K.C., McGuire B., Gubler W.D.,
RA Walker M.A., Cantu D.;
RT "Adaptive genomic structural variation in the grape powdery mildew
RT pathogen, Erysiphe necator.";
RL BMC Genomics 15:1081-1081(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KHJ34373.1}.
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DR EMBL; JNVN01000911; KHJ34373.1; -; Genomic_DNA.
DR STRING; 52586.A0A0B1P7Z8; -.
DR HOGENOM; CLU_003828_0_0_1; -.
DR OMA; ATRFLMN; -.
DR OrthoDB; 20915at2759; -.
DR Proteomes; UP000030854; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
DR Gene3D; 3.40.50.11210; Rap/Ran-GAP; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR035974; Rap/Ran-GAP_sf.
DR InterPro; IPR000331; Rap/Ran_GAP_dom.
DR InterPro; IPR018515; Tuberin-type_domain.
DR InterPro; IPR027107; Tuberin/Ral-act_asu.
DR InterPro; IPR024584; Tuberin_N.
DR PANTHER; PTHR10063; TUBERIN; 1.
DR PANTHER; PTHR10063:SF0; TUBERIN; 1.
DR Pfam; PF11864; DUF3384; 1.
DR Pfam; PF02145; Rap_GAP; 1.
DR Pfam; PF03542; Tuberin; 1.
DR SUPFAM; SSF48371; ARM repeat; 2.
DR SUPFAM; SSF111347; Rap/Ran-GAP; 1.
DR PROSITE; PS50085; RAPGAP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Reference proteome {ECO:0000313|Proteomes:UP000030854}.
FT DOMAIN 1284..1513
FT /note="Rap-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50085"
FT REGION 32..55
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 758..783
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 830..854
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 441..472
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 836..854
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1594 AA; 181030 MW; 7C607907E2E98030 CRC64;
MSPNARDATP ESKSSSGLVN VFKSLTGIRP LKKQNSRSLL PPHQNDVKGY GLRNKNDQDP
PNYNLLLEQL KAGNPLADRV AAAESLRFAI QQHPVNGLSF ILKGAKDLID PVNSKKARTT
GFELLIACIQ NTSLSDPERL AYFRILTSQS KEEDFHWKLA AIIRLTRNGR DLTGFHYEIL
PVLTAWLRQT WVTTSSHRKH ECGIASLSQE TDLALLFELI YDIVKFNFNI SNEQDIGNII
EALLSILIRT QTSDDIRSCI NVFDAIVTYG DVPNSKLMSC VKVLCSVYFN SDVGVQQEVW
KTISNIYISH NGGNAIRIIF KLIREPYLGT KQALYEIRGA LMILEKLFLK NGKSCYPLVP
FSILIKSLER LSIVDNVIIK NDILRLILSL LSNEGKDISK NVMEEEWNLM FDVIRKCAYQ
ILESPRCLTI EHNSETKCSV CNNYENNFVS LAENLQNLIA RIESLLLQHS KNTDFFQWLD
CVKFLVSFHQ HLPETCARLV IDIFIEYRFC YPSDLDWKEN LTLLLRSFFH NRKNSTQTRL
YALKAGSDVF YALEAVNENI NTEITPLFVN LILKDVRDEE DILVLQEVMS LITTVACATC
DNEYFFYIID NIRERILSDH PRFQIFSSTI KKNISSVRKS LFCEEYNALN QTPSNVITVA
FIQMFILCMD KSVRKAQRLF QEILWILGSE DCEVDARVSA LRLLCRLRAD WANRIFLIPF
TASDSLAAIL YRTPDSLSRK QTDDAATFRL SRADEKVLPS PGARSASIGK GHTLSKKAKR
ISCGNPRTGQ NNFPLWMEPD HEYFSHLTSS NVSTILVSFL NFEDKEAKET RDTSLTKSQK
TTTGEIMSNQ NNDKEDQPSL LDIAKYIKLV TRLIQKDCDW EIFSYIIVHL HSQLMNQALF
MAAIPQIKNL REVLCDQIKT NKIQEPPIIS GLRKSDILLC LFQILNALMS YHKHFSKSEE
DEIVRIFVHG VGEKTSKCCI HALSICCHEL PGSTSKMLVS ILTKFSQIIT QSHVAIHILE
FLACLARLPK LYVNFREEEY RIVFAICFRY LQYVRDQKNK EIPIRNSIGC GKSVAGTLLG
ATDTISMESN PHPTTSDDLP EYVYALAHHV IIFWFLSLKL ADRPAQVRWI IKNLISKDIN
GVETIDEQAQ VTIDFMQRVT YADVDQSGPD PSFKKDVFGE INRKRWVIGD SLLTVEQATR
KDWAQITKHQ PSGTSSYLIQ EKIRHPPAHQ TQISTDAMKD TRHSDENIKL PSHLLLQLCA
STPMSGESLR PIPLSECKSI DRAVSNLNRT FTVDSHKVGV IYIGENQTKE AEILSNIQGS
SDYTKFLFGL GTLTKLRGAN FNTQGLDRQT DSDGEYTFCW RDRVTEIVFH VSTQMPTDLE
NDPQCSNKKK HIGNDFVNII FNNSGLPFGF NTFPSAFNFV NIVISPETKL TFVAQRLKPD
MDDAIYKVQV MSKPGFPEIS PAAETKILSL STLPDFIRLV SLNASVFSLA WAHRAGGEHF
SPWRSRLREI RKIREASGHK SSGISPPSTS HIISADSRNV RDSINSLRRS SINFFSQTNV
PLSHRSSDQT SETEIKSIYG KDILLESLDF SKWA
//
