ID A0A0B1PGG2_UNCNE Unreviewed; 1056 AA.
AC A0A0B1PGG2;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Putative linoleate diol synthase {ECO:0000313|EMBL:KHJ35654.1};
GN ORFNames=EV44_g0988 {ECO:0000313|EMBL:KHJ35654.1};
OS Uncinula necator (Grape powdery mildew).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Erysiphales; Erysiphaceae; Erysiphe.
OX NCBI_TaxID=52586 {ECO:0000313|EMBL:KHJ35654.1, ECO:0000313|Proteomes:UP000030854};
RN [1] {ECO:0000313|EMBL:KHJ35654.1, ECO:0000313|Proteomes:UP000030854}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=c {ECO:0000313|Proteomes:UP000030854};
RX PubMed=25487071;
RA Jones L., Riaz S., Morales-Cruz A., Amrine K.C., McGuire B., Gubler W.D.,
RA Walker M.A., Cantu D.;
RT "Adaptive genomic structural variation in the grape powdery mildew
RT pathogen, Erysiphe necator.";
RL BMC Genomics 15:1081-1081(2014).
CC -!- SUBUNIT: Homotetramer. {ECO:0000256|ARBA:ARBA00011881}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KHJ35654.1}.
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DR EMBL; JNVN01000312; KHJ35654.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0B1PGG2; -.
DR STRING; 52586.A0A0B1PGG2; -.
DR HOGENOM; CLU_002329_1_0_1; -.
DR OMA; EEPAHAF; -.
DR OrthoDB; 3322316at2759; -.
DR Proteomes; UP000030854; Unassembled WGS sequence.
DR GO; GO:0051213; F:dioxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0004497; F:monooxygenase activity; IEA:InterPro.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR GO; GO:0004601; F:peroxidase activity; IEA:InterPro.
DR GO; GO:0006631; P:fatty acid metabolic process; IEA:UniProt.
DR GO; GO:0006979; P:response to oxidative stress; IEA:InterPro.
DR CDD; cd20612; CYP_LDS-like_C; 1.
DR CDD; cd09817; linoleate_diol_synthase_like; 1.
DR Gene3D; 1.10.630.10; Cytochrome P450; 1.
DR Gene3D; 1.10.640.10; Haem peroxidase domain superfamily, animal type; 1.
DR InterPro; IPR001128; Cyt_P450.
DR InterPro; IPR036396; Cyt_P450_sf.
DR InterPro; IPR019791; Haem_peroxidase_animal.
DR InterPro; IPR010255; Haem_peroxidase_sf.
DR InterPro; IPR037120; Haem_peroxidase_sf_animal.
DR InterPro; IPR034812; Ppo-like_N.
DR PANTHER; PTHR11903:SF37; LINOLEATE 8R-LIPOXYGENASE-RELATED; 1.
DR PANTHER; PTHR11903; PROSTAGLANDIN G/H SYNTHASE; 1.
DR Pfam; PF03098; An_peroxidase; 2.
DR Pfam; PF00067; p450; 1.
DR SUPFAM; SSF48264; Cytochrome P450; 1.
DR SUPFAM; SSF48113; Heme-dependent peroxidases; 1.
DR PROSITE; PS50292; PEROXIDASE_3; 1.
PE 4: Predicted;
KW Dioxygenase {ECO:0000256|ARBA:ARBA00022964};
KW Heme {ECO:0000256|PIRSR:PIRSR619791-2};
KW Iron {ECO:0000256|PIRSR:PIRSR619791-2};
KW Metal-binding {ECO:0000256|PIRSR:PIRSR619791-2};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00022964};
KW Reference proteome {ECO:0000313|Proteomes:UP000030854}.
FT BINDING 360
FT /ligand="heme b"
FT /ligand_id="ChEBI:CHEBI:60344"
FT /ligand_part="Fe"
FT /ligand_part_id="ChEBI:CHEBI:18248"
FT /note="axial binding residue"
FT /evidence="ECO:0000256|PIRSR:PIRSR619791-2"
SQ SEQUENCE 1056 AA; 117231 MW; 1929C8F3BDEBF8F1 CRC64;
MGPSQIKALI GTIKRKPSEA PLNGETSPEK TTVFHDLTHL GVKNTKTVAQ AISTLASGQP
LNDKDELLEN GVEMLQSLPL NSSLSQIVSN DFIAMLWNDL PHPPSTLSGP SARFRQHDGS
GNNPWVPNMG KAGTPYSRTV PPMKPKGPNL PDPELVFEYL LKRNGPFREH PSGLNRLFFS
FATIVIHECF QTSRTNPWVN ETSSYVDLST LYGNTEKEQI RVRTYENGRL FPDTIASERI
MMMPPGVVAV LLLFSRNHNH IAESLLSINE DGNFKDWNTL SDEQKLIQDN EIFQLARNIN
VGYFASVVLK DYVAAILNTP RANSTWSLDL GAEIKKGANR AERATGNVVS IEFVVLYHWH
AALSAADDKW MENLFRDEFP DLGSVDDITV EMFMKVMKTH GHKLFSTPAK EWTFGGLKRS
PSGYFSDYEL GELIKDCIEE PAHAFGAHGT PASLKVVDIL GQLQAREVFN VCTMNEFRRY
LNLVPYKDFK DWCGDKETAQ AAELLYGHID NLELYPGLMA EVTKPPRAGS GVCPGQTTGR
GILGDAVALI RGDRFLSYDF NSSTLTNWGV SKLQSLPGGA YGGMLPDLLM KGLPGAFPGT
SIYTLLSFYT PSAAKGILKG NKATSEYTLD RPPSGLEVLG IHTQEGVLKA FEDRETFRVM
YMKAIKECTS GFEFMLGWDD AARHDPRSQL LYKAYFDEGF ETKISNFFSE TVANLIKEKS
LKYSGSKRSI DIVRDVTNVA PILWLAQRFA IPLKTTKKPH GVLTVNELFK VYLVLFIYQS
FNIIPSAEWK LREGARKAGS VLRSIHTAHL KTQQGIKEGL VDWLAKDSAF EVGPEADRLY
HALNDTKLPI GDLVASCILL AAPVAGNITQ QASLLIDLYL SPGYEKYKER IIELAHQDTS
AAERELQGFV YEGMRHAGVV PGVPRVVSKD VTFVDGTRGP LELKSGQIVL IATSKAAMDP
IAFPNPEIID PHRGFKSYSL LGHGLHFCFG ARIVGYSLAA TLRQVFKLKN IRRAPGKRGV
FSYVEHELAG VQMRMYLDQN ALESPIPTTL TIEYDE
//
