ID   A0A0B1S6B8_OESDE        Unreviewed;       492 AA.
AC   A0A0B1S6B8;
DT   04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT   04-MAR-2015, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Patched family protein {ECO:0000313|EMBL:KHJ80474.1};
DE   Flags: Fragment;
GN   ORFNames=OESDEN_19851 {ECO:0000313|EMBL:KHJ80474.1};
OS   Oesophagostomum dentatum (Nodular worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Strongylidae; Oesophagostomum.
OX   NCBI_TaxID=61180 {ECO:0000313|EMBL:KHJ80474.1, ECO:0000313|Proteomes:UP000053660};
RN   [1] {ECO:0000313|EMBL:KHJ80474.1, ECO:0000313|Proteomes:UP000053660}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OD-Hann {ECO:0000313|EMBL:KHJ80474.1,
RC   ECO:0000313|Proteomes:UP000053660};
RA   Mitreva M.;
RT   "Draft genome of the hookworm Oesophagostomum dentatum.";
RL   Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the patched family.
CC       {ECO:0000256|ARBA:ARBA00005585}.
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DR   EMBL; KN600553; KHJ80474.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0B1S6B8; -.
DR   Proteomes; UP000053660; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 1.
DR   InterPro; IPR003392; Ptc/Disp.
DR   InterPro; IPR000731; SSD.
DR   PANTHER; PTHR10796; PATCHED-RELATED; 1.
DR   PANTHER; PTHR10796:SF181; SSD DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF02460; Patched; 1.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 1.
DR   PROSITE; PS50156; SSD; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053660};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        117..138
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        145..169
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        175..197
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        218..240
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        246..271
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        320..340
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          113..271
FT                   /note="SSD"
FT                   /evidence="ECO:0000259|PROSITE:PS50156"
FT   NON_TER         492
FT                   /evidence="ECO:0000313|EMBL:KHJ80474.1"
SQ   SEQUENCE   492 AA;  55602 MW;  F1277CE891676B91 CRC64;
     MFKLFLISDR SFLNRSVDEL TLAQLSDAFQ FDSGGMTHLL GGITLDSEKR VAGAKAMMLP
     YALRHSSQGE DWLAEQWELR LADFLLHYDS PVIRASWWTY ETLAAESARD RNQLISMLGP
     CFIAVSLFTI AMCCVCSWRR SRPWLAIGGV ISAALAIISA VGLLLLLGFG MTSVAYSMPF
     IVFSVGVDNV FMLLSAWRSS PSHETLEKRM EETFAEAGVS ITVTSLTDFI SFAVGCATPF
     PSVQMFCAYA VTAVVFTYIY QLTFFAGIMV YTNKREMANR NCLTFRKIKK DTDWSKVGLD
     RSFEKNHMLS QFFRTTYSDL LLNPFVRALI IAAFLAYLAL ATYGCTEVKL GLEPNDLLPD
     NSYGKRTLRL AEKYFSGKYY GSSLHVWMYN LSTVDYGSRR MWAVLNKEIE LYEHTEFTGT
     ADSWLRTFLA FVKQSGLLLT QDNFVYILRN VFLAQPQFGK YRRLAFSSRV YTPTHTLNSP
     EISATSFSTK AP
//