ID   A0A0B1TFB7_OESDE        Unreviewed;       782 AA.
AC   A0A0B1TFB7;
DT   04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT   04-MAR-2015, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=Reverse transcriptase {ECO:0000313|EMBL:KHJ94801.1};
GN   ORFNames=OESDEN_05265 {ECO:0000313|EMBL:KHJ94801.1};
OS   Oesophagostomum dentatum (Nodular worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Strongylidae; Oesophagostomum.
OX   NCBI_TaxID=61180 {ECO:0000313|EMBL:KHJ94801.1, ECO:0000313|Proteomes:UP000053660};
RN   [1] {ECO:0000313|EMBL:KHJ94801.1, ECO:0000313|Proteomes:UP000053660}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OD-Hann {ECO:0000313|EMBL:KHJ94801.1,
RC   ECO:0000313|Proteomes:UP000053660};
RA   Mitreva M.;
RT   "Draft genome of the hookworm Oesophagostomum dentatum.";
RL   Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KN550196; KHJ94801.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0B1TFB7; -.
DR   Proteomes; UP000053660; Unassembled WGS sequence.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR   CDD; cd09275; RNase_HI_RT_DIRS1; 1.
DR   CDD; cd03714; RT_DIRS1; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR036397; RNaseH_sf.
DR   InterPro; IPR000477; RT_dom.
DR   PANTHER; PTHR33050; REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR33050:SF8; RIBONUCLEASE H; 1.
DR   Pfam; PF00078; RVT_1; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   PROSITE; PS50878; RT_POL; 1.
PE   4: Predicted;
KW   Nucleotidyltransferase {ECO:0000313|EMBL:KHJ94801.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053660};
KW   RNA-directed DNA polymerase {ECO:0000313|EMBL:KHJ94801.1};
KW   Transferase {ECO:0000313|EMBL:KHJ94801.1}.
FT   DOMAIN          193..375
FT                   /note="Reverse transcriptase"
FT                   /evidence="ECO:0000259|PROSITE:PS50878"
SQ   SEQUENCE   782 AA;  88653 MW;  C864104B29C52A50 CRC64;
     MPASVVGYLE IAATLLSGSL RDVIVLRRER VLRGLGLDPR RAMPSYRRLP LAGSTVVQRI
     TQTVHPELFG RELRDELAAG ESALAKSVQK LRQRSRHERS GNKAKRLVEI HSPKINQAAA
     TPVQQVFSER IAGRFQDFAD CWFKLTNDPL VRNTVMGYTL PFRETPSLTV PQYLCRHTSE
     ALSTALEELL EKGAIAKARK GSPVWISTMF PIPKKDGTWR PIINLKPLNQ FLKVPHFKME
     GLHLVPEIVK QGDYCAKIDM TDAYFAVNIA EDSRPFLAFF WGSEIFWFTC LPFGLATAPY
     IYTKLMRVIM EHLRTHGIRL ISYLDDWAFF AETAELLHQQ LDYALRTFEN LGLRINREKS
     ILKPCQRIEF LGVILDTSLG VFELPQSKLA KIRDEAESLL CKGVVKAREI AKFLGRANFV
     GLVIPFSTHF TRALQGDLAR SVSPHDTKSF ENQVSLSERA REDLAWFRDH ICEHSGASFC
     RNSPDITMSC DASKAGWGAV CCGLKTGGRW SRDESLDHIN LLELKAIYFG LKSFGKKWRD
     TTVLIESDNT AAIAYVKKRG GTKSKHMSTV AKQIWEWTLG KNIRLLVTHR PGIQNREADK
     ESRTFTREHA EWSLDPQTAL TVFTHFGKPE VDLFASRLNA KLPHYYSLNY DPGAERIDSF
     AQNWSGIFGY AFPPFNLIGR TIRKAICDGT RIILITPLWK SQSWFPLALE HACRPPTLLR
     SQNLLLVDRD GNPHPLLKQK RFCLVAWEIS PTPGKALALK LRRSARYWPA GLLTLSDNTN
     QP
//