ID   A0A0B1TR11_OESDE        Unreviewed;       257 AA.
AC   A0A0B1TR11;
DT   04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT   04-MAR-2015, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=Sodium/calcium exchanger membrane region domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=OESDEN_02175 {ECO:0000313|EMBL:KHJ97840.1};
OS   Oesophagostomum dentatum (Nodular worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Strongylidae; Oesophagostomum.
OX   NCBI_TaxID=61180 {ECO:0000313|EMBL:KHJ97840.1, ECO:0000313|Proteomes:UP000053660};
RN   [1] {ECO:0000313|EMBL:KHJ97840.1, ECO:0000313|Proteomes:UP000053660}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OD-Hann {ECO:0000313|EMBL:KHJ97840.1,
RC   ECO:0000313|Proteomes:UP000053660};
RA   Mitreva M.;
RT   "Draft genome of the hookworm Oesophagostomum dentatum.";
RL   Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the ZIP transporter (TC 2.A.5) family.
CC       {ECO:0000256|ARBA:ARBA00006939}.
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DR   EMBL; KN549391; KHJ97840.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0B1TR11; -.
DR   Proteomes; UP000053660; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046873; F:metal ion transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR003689; ZIP.
DR   PANTHER; PTHR12191; SOLUTE CARRIER FAMILY 39; 1.
DR   PANTHER; PTHR12191:SF32; ZRT (ZRT), IRT-(IRT-) LIKE PROTEIN TRANSPORTER; 1.
DR   Pfam; PF02535; Zip; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053660};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        204..224
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        236..254
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   257 AA;  28546 MW;  2E214E478B6617BE CRC64;
     MNNAFARTIL LVVAVLVTTS LRCYEFHRRY RTERWTKGGE AKAVYSFFKI MGTPLAMMLA
     NFQARNNFLE TVNSDISNNQ NHFLNVINND VSKALSVAKP RHAEDVPSDR RKEKNDDEVS
     VSVKIVEKHV VDPSNIEVAS VAYMIIFGSS ANNFVDGMSM GAAFSDSLLR GLSIGIAVVS
     QQFPQELGTL AILINSGLGF RRALLYNFIP IFLSYLGFAC GVLLDNIDDS YDDYIFSISS
     GMYLYIFLGT LVGTKLC
//