ID A0A0B2UVL9_TOXCA Unreviewed; 619 AA.
AC A0A0B2UVL9;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Potassium voltage-gated channel subfamily B member 1 {ECO:0000313|EMBL:KHN73463.1};
GN Name=KCNB1 {ECO:0000313|EMBL:KHN73463.1};
GN ORFNames=Tcan_18267 {ECO:0000313|EMBL:KHN73463.1};
OS Toxocara canis (Canine roundworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Ascaridomorpha; Ascaridoidea; Toxocaridae; Toxocara.
OX NCBI_TaxID=6265 {ECO:0000313|EMBL:KHN73463.1, ECO:0000313|Proteomes:UP000031036};
RN [1] {ECO:0000313|EMBL:KHN73463.1, ECO:0000313|Proteomes:UP000031036}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PN_DK_2014 {ECO:0000313|EMBL:KHN73463.1};
RA Zhu X.-Q., Korhonen P.K., Cai H., Young N.D., Nejsum P.,
RA von Samson-Himmelstjerna G., Boag P.R., Tan P., Li Q., Min J., Yang Y.,
RA Wang X., Fang X., Hall R.S., Hofmann A., Sternberg P.W., Jex A.R.,
RA Gasser R.B.;
RT "Genetic blueprint of the zoonotic pathogen Toxocara canis.";
RL Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KHN73463.1}.
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DR EMBL; JPKZ01003108; KHN73463.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0B2UVL9; -.
DR STRING; 6265.A0A0B2UVL9; -.
DR OMA; GVYDQQQ; -.
DR Proteomes; UP000031036; Unassembled WGS sequence.
DR GO; GO:0008076; C:voltage-gated potassium channel complex; IEA:InterPro.
DR GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR CDD; cd18317; BTB_POZ_Kv; 1.
DR Gene3D; 1.10.287.70; -; 2.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 1.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR003968; K_chnl_volt-dep_Kv.
DR InterPro; IPR003971; K_chnl_volt-dep_Kv9.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR003131; T1-type_BTB.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR11537; VOLTAGE-GATED POTASSIUM CHANNEL; 1.
DR PANTHER; PTHR11537:SF287; VOLTAGE-GATED POTASSIUM CHANNEL SUBUNIT KVS-4-RELATED; 1.
DR Pfam; PF02214; BTB_2; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR PRINTS; PR00169; KCHANNEL.
DR PRINTS; PR01494; KV9CHANNEL.
DR PRINTS; PR01491; KVCHANNEL.
DR SUPFAM; SSF54695; POZ domain; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 2.
PE 4: Predicted;
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Potassium {ECO:0000256|ARBA:ARBA00022958};
KW Potassium channel {ECO:0000256|ARBA:ARBA00022826};
KW Potassium transport {ECO:0000256|ARBA:ARBA00022538};
KW Reference proteome {ECO:0000313|Proteomes:UP000031036};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448};
KW Voltage-gated channel {ECO:0000256|ARBA:ARBA00022882}.
FT TRANSMEM 247..268
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 324..348
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 400..421
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 451..472
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 528..549
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 97..188
FT /note="Potassium channel tetramerisation-type BTB"
FT /evidence="ECO:0000259|Pfam:PF02214"
FT DOMAIN 246..480
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT REGION 571..619
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 579..612
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 619 AA; 70080 MW; 1BEABF7FC6954AAE CRC64;
MNTVVLQGTL MATSHGIHRI NRHNRNSQLT SATTRLGRYL KMNKRTPTRP QHDDENVVVS
CEEASEKLLP NGETAKDDEQ QIAEVLSEGV HSVRFMRVNV GGSRFLLRTS TINARHCGRL
YWMLRMSHEQ RLTMVDAYFE DFREYYFERP PLLFHIVYQF YLTGLIHQPL HVCPQDLLDE
LNYWGIAPGE YLAQCCCIDQ QTSNTEQNED EEESDKPNYF KHLRCGEYRR KVWNLIEKPT
SSTAAQIFAA FSVLFLLISI SGLVLGSLPE LQVPISKQNA SGKSTMIEME PHPFLGHLEY
VCIVWFTFEY ASKMLVTYDR RKTFLKLLNL IDLMAILPFL IEIALMFVGI NTDDLRDLKG
AFLVIRILRV LRVIRVLKLG RYSSGLQMFG KTLKASFRQL GMMAMVVLTG VIFFSTLVYF
LEKDEPGSEF YSIPAACWWV WRPNAGNIGK LVATGAIACG VLVLALPITI IVDNFMKVAE
GERNSGVYDQ QQQRFRRIGP RGRIPIVFFS GYGDLTPATV LGKLVATGAI ACGVLVLALP
ITIIVDNFMK VAEGERNSGV YDQQQQRFRR IGPRGRIPIS DQASTTSPIK NRRTAPNDSF
TDKGNSTTFI DSDHSSGKK
//
