ID   A0A0B2UXP8_TOXCA        Unreviewed;       636 AA.
AC   A0A0B2UXP8;
DT   04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT   04-MAR-2015, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   SubName: Full=Intermediate filament protein A {ECO:0000313|EMBL:KHN73857.1};
DE   Flags: Fragment;
GN   ORFNames=Tcan_12338 {ECO:0000313|EMBL:KHN73857.1};
OS   Toxocara canis (Canine roundworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Ascaridomorpha; Ascaridoidea; Toxocaridae; Toxocara.
OX   NCBI_TaxID=6265 {ECO:0000313|EMBL:KHN73857.1, ECO:0000313|Proteomes:UP000031036};
RN   [1] {ECO:0000313|EMBL:KHN73857.1, ECO:0000313|Proteomes:UP000031036}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PN_DK_2014 {ECO:0000313|EMBL:KHN73857.1};
RA   Zhu X.-Q., Korhonen P.K., Cai H., Young N.D., Nejsum P.,
RA   von Samson-Himmelstjerna G., Boag P.R., Tan P., Li Q., Min J., Yang Y.,
RA   Wang X., Fang X., Hall R.S., Hofmann A., Sternberg P.W., Jex A.R.,
RA   Gasser R.B.;
RT   "Genetic blueprint of the zoonotic pathogen Toxocara canis.";
RL   Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the intermediate filament family.
CC       {ECO:0000256|RuleBase:RU000685}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KHN73857.1}.
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DR   EMBL; JPKZ01002995; KHN73857.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0B2UXP8; -.
DR   STRING; 6265.A0A0B2UXP8; -.
DR   OMA; QQCANMA; -.
DR   Proteomes; UP000031036; Unassembled WGS sequence.
DR   GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.5.170; -; 1.
DR   Gene3D; 2.60.40.1260; Lamin Tail domain; 1.
DR   Gene3D; 1.20.5.500; Single helix bin; 1.
DR   Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 2.
DR   InterPro; IPR018039; IF_conserved.
DR   InterPro; IPR039008; IF_rod_dom.
DR   InterPro; IPR016451; Intermed_filament_ifa/ifb.
DR   InterPro; IPR001322; Lamin_tail_dom.
DR   InterPro; IPR036415; Lamin_tail_dom_sf.
DR   PANTHER; PTHR45721:SF12; INTERMEDIATE FILAMENT PROTEIN IFA-1; 1.
DR   PANTHER; PTHR45721; LAMIN DM0-RELATED; 1.
DR   Pfam; PF00038; Filament; 2.
DR   Pfam; PF00932; LTD; 1.
DR   PIRSF; PIRSF005546; Intermed_filamnt_Ifb-2; 2.
DR   SMART; SM01391; Filament; 1.
DR   SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 2.
DR   SUPFAM; SSF74853; Lamin A/C globular tail domain; 1.
DR   PROSITE; PS00226; IF_ROD_1; 1.
DR   PROSITE; PS51842; IF_ROD_2; 1.
DR   PROSITE; PS51841; LTD; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW   ECO:0000256|RuleBase:RU000685};
KW   Reference proteome {ECO:0000313|Proteomes:UP000031036}.
FT   DOMAIN          111..480
FT                   /note="IF rod"
FT                   /evidence="ECO:0000259|PROSITE:PS51842"
FT   DOMAIN          513..631
FT                   /note="LTD"
FT                   /evidence="ECO:0000259|PROSITE:PS51841"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          101..255
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          385..479
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KHN73857.1"
SQ   SEQUENCE   636 AA;  73281 MW;  7AEC9BE025EB1515 CRC64;
     QPSPSPAKMS DYKLSSSYGD HTTTTEFRIT NKSSMDQVPL PEYRSTIAAR PGYNRAIGSS
     ISMTPFGSMS SGGGRILKTV TEIGSSSIHS SGLSPFGQNA ASTIRDTRER EKKEMSDLND
     RLASYIEKVR FLEAQNRKLA ADLDLLRGRW GKDTLSVRAM YEGELQEARK LVDDTNRQRE
     ELEKEIRKLL DELSECRRRY EDALRGHHAD RDRIDELLVQ LSGLEAEINL LRRRIANIEE
     EIARIKKENL HFANELAKAR SDLDQETLNR IDFQNQVQTL LEEIDFMRRV HDQEIAELQA
     MASRDTTPEN REYFKNELAS AIRDIRAEYD QNELASAIRD IRAEYDQICN VNRTDMESWY
     KLKVQEIQTQ STRQNLEQNY AKEEVKRLRV QLTELRGKLA DLEGRNSLLE KQTQELNYQL
     EDDQRSYEAA LNDRDAQIRK MREECQALML ELQMLLDTKQ TLDAEIAIYR KMLEGEENRA
     GLRQLVEQVV KTHGLTQVAE TESLRVLKGE TASRTSFQRS AKGNVSIQET APDGRFVVLE
     NTHRSKEEHI GEWKLKRKID GKREIVYTFP RDYILYPGKS VKIWARGQGG IHSPPEQLVF
     DMEDSFGSGS NVQTILFNRE GEERATHIQR SSHTIS
//