ID A0A0B2UXW2_TOXCA Unreviewed; 586 AA.
AC A0A0B2UXW2;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE SubName: Full=Bromodomain-containing protein 8 {ECO:0000313|EMBL:KHN74054.1};
DE Flags: Fragment;
GN Name=Brd8 {ECO:0000313|EMBL:KHN74054.1};
GN ORFNames=Tcan_05429 {ECO:0000313|EMBL:KHN74054.1};
OS Toxocara canis (Canine roundworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Ascaridomorpha; Ascaridoidea; Toxocaridae; Toxocara.
OX NCBI_TaxID=6265 {ECO:0000313|EMBL:KHN74054.1, ECO:0000313|Proteomes:UP000031036};
RN [1] {ECO:0000313|EMBL:KHN74054.1, ECO:0000313|Proteomes:UP000031036}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PN_DK_2014 {ECO:0000313|EMBL:KHN74054.1};
RA Zhu X.-Q., Korhonen P.K., Cai H., Young N.D., Nejsum P.,
RA von Samson-Himmelstjerna G., Boag P.R., Tan P., Li Q., Min J., Yang Y.,
RA Wang X., Fang X., Hall R.S., Hofmann A., Sternberg P.W., Jex A.R.,
RA Gasser R.B.;
RT "Genetic blueprint of the zoonotic pathogen Toxocara canis.";
RL Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KHN74054.1}.
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DR EMBL; JPKZ01002978; KHN74054.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0B2UXW2; -.
DR STRING; 6265.A0A0B2UXW2; -.
DR Proteomes; UP000031036; Unassembled WGS sequence.
DR Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR PANTHER; PTHR15398; BROMODOMAIN-CONTAINING PROTEIN 8; 1.
DR PANTHER; PTHR15398:SF4; BROMODOMAIN-CONTAINING PROTEIN 8; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 1.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|PROSITE-ProRule:PRU00035};
KW Reference proteome {ECO:0000313|Proteomes:UP000031036}.
FT DOMAIN 459..529
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT REGION 1..423
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 37..66
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 85..99
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 100..137
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 146..169
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 174..201
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 210..247
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 271..292
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 308..335
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 342..377
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 389..408
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KHN74054.1"
SQ SEQUENCE 586 AA; 64624 MW; 226C5E1EE5B9467E CRC64;
GSPRRALLPI DGAAQKDSPV KVETAENVME VDTTPTDANE AKPDDEVPNA DNGKTEDQHE
GHMQTRQMRS TVEGSGGASA AAARVEEKPA EKRHLRNINK VASQSDSSSS RSVLRPQRLS
PRKPSTDTTV RSESDTTKGQ THTLELRNRR GSNSGQTIEP ASADGPPSQS LRSRRVLEKS
EENEDLSSQR RRSERHRGTD SSGSAGELSP GKRKRPHGAE EGADGARSDE EGAKWLGVKR
RKLSFRETAT SSEVGEGQDG GKVMEIHMEV QSSPEPDRNE ANLRKIEEGT LPEANGEKQS
NRRGSLRSAT AREQEPKKEE TTSDVKDRAE TTGGRVKHGA IETVTVESDS DEDKPLGDIR
SGIMAAKKEE EVLSKTSEKM GETPSQKTVE GESTRKRSLE RQKGRSRPTR SGVEGTPKVK
SDALRTPTFS LRRHSRREEL DETSIEQKAF MTSVWRMVSS HRHAAIFAQP VSDSIARGYS
KVVKSRMDLG TLKKQLDSGR VADMTEFKRR LLLMFANAVM FNSTGHDVNN YAKEMAADSL
NSLKTMQKDI LNMKEGAHVT RSAAAAEEKI DSFPLIWERQ SLTTRH
//
