ID   A0A0B2V0Z2_TOXCA        Unreviewed;       483 AA.
AC   A0A0B2V0Z2;
DT   04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT   04-MAR-2015, sequence version 1.
DT   03-MAY-2023, entry version 20.
DE   SubName: Full=Ceramide kinase {ECO:0000313|EMBL:KHN75077.1};
GN   Name=Cerk {ECO:0000313|EMBL:KHN75077.1};
GN   ORFNames=Tcan_16251 {ECO:0000313|EMBL:KHN75077.1};
OS   Toxocara canis (Canine roundworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Ascaridomorpha; Ascaridoidea; Toxocaridae; Toxocara.
OX   NCBI_TaxID=6265 {ECO:0000313|EMBL:KHN75077.1, ECO:0000313|Proteomes:UP000031036};
RN   [1] {ECO:0000313|EMBL:KHN75077.1, ECO:0000313|Proteomes:UP000031036}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PN_DK_2014 {ECO:0000313|EMBL:KHN75077.1};
RA   Zhu X.-Q., Korhonen P.K., Cai H., Young N.D., Nejsum P.,
RA   von Samson-Himmelstjerna G., Boag P.R., Tan P., Li Q., Min J., Yang Y.,
RA   Wang X., Fang X., Hall R.S., Hofmann A., Sternberg P.W., Jex A.R.,
RA   Gasser R.B.;
RT   "Genetic blueprint of the zoonotic pathogen Toxocara canis.";
RL   Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KHN75077.1}.
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DR   EMBL; JPKZ01002783; KHN75077.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0B2V0Z2; -.
DR   STRING; 6265.A0A0B2V0Z2; -.
DR   OMA; RCCISSK; -.
DR   Proteomes; UP000031036; Unassembled WGS sequence.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.200.40; -; 1.
DR   InterPro; IPR017438; ATP-NAD_kinase_N.
DR   InterPro; IPR001206; Diacylglycerol_kinase_cat_dom.
DR   InterPro; IPR016064; NAD/diacylglycerol_kinase_sf.
DR   PANTHER; PTHR12358:SF6; CERAMIDE KINASE, ISOFORM A; 1.
DR   PANTHER; PTHR12358; SPHINGOSINE KINASE; 1.
DR   Pfam; PF00781; DAGK_cat; 1.
DR   SMART; SM00046; DAGKc; 1.
DR   SUPFAM; SSF111331; NAD kinase/diacylglycerol kinase-like; 1.
DR   PROSITE; PS50146; DAGK; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000313|EMBL:KHN75077.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000031036};
KW   Transferase {ECO:0000313|EMBL:KHN75077.1}.
FT   DOMAIN          160..313
FT                   /note="DAGKc"
FT                   /evidence="ECO:0000259|PROSITE:PS50146"
FT   REGION          1..37
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..24
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   483 AA;  54031 MW;  786A7BCD36D474BA CRC64;
     MSHNSRRALQ QVYPAANRAM STEKLNSEPR MDESGAHSVM AADIRSTDGK YHRMVFDRSK
     ELLEFTVTGG DTKQPRSMLK DINELLSVRG TPIIMRRGLP VDLNKSAKQA DTPNSLFFYF
     AEKRDKCKWR IREVIAVFTT SSEKKHWLDA LNCALKALPK RPKTLLIFVN PYGGKGRAKK
     IYAKQVELIL ALADIECEVV MTQRANHAFD ELKQLVASKW NSIDGVVSVG GDGLFNECLS
     AIVCRSQEEA DKDITDINID TLETPRMRFG IIGAGSANSI VSSVHGTDDC PTAAIHIAMG
     SQCPVDVCTV HRGDDLMRIS ANAISYGWLG DVLADSELYR WMGPFRYQFS ALRTTILNPS
     YFGRVSFCLI NEGDPGVVFP KCAQGCTLCE RLHPRLIKYF GRELDLNQPI KKRGRCCISS
     KKKLSNIVTV EASSSSDQIL WSLHPRLIKY FGRELDLNQP IKKRGRCCIS SKKKLSNIVT
     VEV
//