ID   A0A0B2V5H7_TOXCA        Unreviewed;       642 AA.
AC   A0A0B2V5H7;
DT   04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT   04-MAR-2015, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=Sulfate permease family protein 3 {ECO:0000313|EMBL:KHN76798.1};
GN   Name=sulp-3 {ECO:0000313|EMBL:KHN76798.1};
GN   ORFNames=Tcan_14092 {ECO:0000313|EMBL:KHN76798.1};
OS   Toxocara canis (Canine roundworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Ascaridomorpha; Ascaridoidea; Toxocaridae; Toxocara.
OX   NCBI_TaxID=6265 {ECO:0000313|EMBL:KHN76798.1, ECO:0000313|Proteomes:UP000031036};
RN   [1] {ECO:0000313|EMBL:KHN76798.1, ECO:0000313|Proteomes:UP000031036}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PN_DK_2014 {ECO:0000313|EMBL:KHN76798.1};
RA   Zhu X.-Q., Korhonen P.K., Cai H., Young N.D., Nejsum P.,
RA   von Samson-Himmelstjerna G., Boag P.R., Tan P., Li Q., Min J., Yang Y.,
RA   Wang X., Fang X., Hall R.S., Hofmann A., Sternberg P.W., Jex A.R.,
RA   Gasser R.B.;
RT   "Genetic blueprint of the zoonotic pathogen Toxocara canis.";
RL   Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC       ECO:0000256|RuleBase:RU362052}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU362052}.
CC   -!- SIMILARITY: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
CC       {ECO:0000256|RuleBase:RU362052}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KHN76798.1}.
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DR   EMBL; JPKZ01002430; KHN76798.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0B2V5H7; -.
DR   STRING; 6265.A0A0B2V5H7; -.
DR   OMA; ITIAYKE; -.
DR   Proteomes; UP000031036; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008509; F:monoatomic anion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0098661; P:inorganic anion transmembrane transport; IEA:UniProtKB-UniRule.
DR   CDD; cd07042; STAS_SulP_like_sulfate_transporter; 1.
DR   Gene3D; 3.30.750.24; STAS domain; 1.
DR   InterPro; IPR011547; SLC26A/SulP_dom.
DR   InterPro; IPR001902; SLC26A/SulP_fam.
DR   InterPro; IPR002645; STAS_dom.
DR   InterPro; IPR036513; STAS_dom_sf.
DR   PANTHER; PTHR11814:SF257; ANION TRANSPORTER SULP-7D; 1.
DR   PANTHER; PTHR11814; SULFATE TRANSPORTER; 1.
DR   Pfam; PF01740; STAS; 1.
DR   Pfam; PF00916; Sulfate_transp; 1.
DR   SUPFAM; SSF52091; SpoIIaa-like; 1.
DR   PROSITE; PS50801; STAS; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362052};
KW   Reference proteome {ECO:0000313|Proteomes:UP000031036};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU362052};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU362052}; Transport {ECO:0000256|RuleBase:RU362052}.
FT   TRANSMEM        12..37
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362052"
FT   TRANSMEM        43..60
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362052"
FT   TRANSMEM        118..138
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362052"
FT   TRANSMEM        202..222
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362052"
FT   TRANSMEM        234..253
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362052"
FT   TRANSMEM        289..308
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362052"
FT   TRANSMEM        360..379
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362052"
FT   TRANSMEM        415..443
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362052"
FT   DOMAIN          466..615
FT                   /note="STAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50801"
SQ   SEQUENCE   642 AA;  71375 MW;  32E1F5A1EA6B665D CRC64;
     MQENSRCAIK SIYVIGITIA YKESVHHCLL IGIAYAYMIK LPAAYGLYAS IFPSFFYMFF
     GTSRHASIGG FAIITVMTVQ AIRDAEGKYS EELALLHSNS TTFLELSEDN DSLQQLRCAF
     AIGLTLCVGA AQLLMAVLQM DFLTAYLSDQ LVTGFSLGAA VHVIATQMKD LVDLTGLPRR
     SGTGKIFLKI YDFFANLYRA NWYAGVTSLV GGVALMLGKW IVGVLINKYF HRSFPVPFEL
     LLVIFATLFS TVLKLHTEHD VRVVGTIPTG LPSPSLPPFG IISYVWKDSI SMAIVIVAVH
     VSVAKILANK HRYHVDNKQE LYALGISNIL ASFFPVFPVS CGLGRAFICS EIGSKTQLKT
     IFSCAFLIVV ILFVGPYLYN LPMCILATIV VLVLKAVFIK IAEVPHLWRC SKIDCIILVF
     SCFVTIVFNV VLGLIISVVF TLITIPIRYQ FSPFDFEYSI YVEAESYHRV EDNLNVFVFR
     LNGPVLYMNA HSIRARAIKK FAEWKAETRR TNFSYREQQS LVGATVKVAP GAAIKKEVSN
     GSTLLVVIDF SAVPFIDICA AESIRKLIND LTADGVEVSL ANVSDELNER LYRFGIIQDV
     DSRLGESVAQ VVKHLNSKRK ILDVHFENVI GLIVNDENSW FL
//