ID A0A0B2V6K9_TOXCA Unreviewed; 721 AA.
AC A0A0B2V6K9;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Semaphorin-1A {ECO:0000313|EMBL:KHN79076.1};
GN Name=smp-1 {ECO:0000313|EMBL:KHN79076.1};
GN ORFNames=Tcan_11172 {ECO:0000313|EMBL:KHN79076.1};
OS Toxocara canis (Canine roundworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Ascaridomorpha; Ascaridoidea; Toxocaridae; Toxocara.
OX NCBI_TaxID=6265 {ECO:0000313|EMBL:KHN79076.1, ECO:0000313|Proteomes:UP000031036};
RN [1] {ECO:0000313|EMBL:KHN79076.1, ECO:0000313|Proteomes:UP000031036}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PN_DK_2014 {ECO:0000313|EMBL:KHN79076.1};
RA Zhu X.-Q., Korhonen P.K., Cai H., Young N.D., Nejsum P.,
RA von Samson-Himmelstjerna G., Boag P.R., Tan P., Li Q., Min J., Yang Y.,
RA Wang X., Fang X., Hall R.S., Hofmann A., Sternberg P.W., Jex A.R.,
RA Gasser R.B.;
RT "Genetic blueprint of the zoonotic pathogen Toxocara canis.";
RL Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00352}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KHN79076.1}.
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DR EMBL; JPKZ01001948; KHN79076.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0B2V6K9; -.
DR STRING; 6265.A0A0B2V6K9; -.
DR OMA; KCRALVG; -.
DR Proteomes; UP000031036; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0030215; F:semaphorin receptor binding; IEA:InterPro.
DR GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR Gene3D; 3.30.1680.10; ligand-binding face of the semaphorins, domain 2; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR002165; Plexin_repeat.
DR InterPro; IPR016201; PSI.
DR InterPro; IPR001627; Semap_dom.
DR InterPro; IPR036352; Semap_dom_sf.
DR InterPro; IPR027231; Semaphorin.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR11036; SEMAPHORIN; 1.
DR PANTHER; PTHR11036:SF127; SEMAPHORIN-1A; 1.
DR Pfam; PF01437; PSI; 1.
DR Pfam; PF01403; Sema; 1.
DR SMART; SM00423; PSI; 1.
DR SMART; SM00630; Sema; 1.
DR SUPFAM; SSF103575; Plexin repeat; 1.
DR SUPFAM; SSF101912; Sema domain; 1.
DR PROSITE; PS51004; SEMA; 1.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Neurogenesis {ECO:0000256|ARBA:ARBA00022902};
KW Reference proteome {ECO:0000313|Proteomes:UP000031036};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 589..610
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 49..501
FT /note="Sema"
FT /evidence="ECO:0000259|PROSITE:PS51004"
SQ SEQUENCE 721 AA; 79610 MW; 69AFDC26B0112A8D CRC64;
MLDENKSGTD GTKQNEMYGY VEFILRIYAE MISGYYQLVS VHSGRRFGGV PLASSEGNAE
RESDHFKLLA SDRNSLMVGA RDAVYNVSMA SMEVQHTIEW APNGQTVEDC LMKGKSRLEC
HNYIRVMVRQ ANGRCLICGT YAFSPKCREY VYSGDEHSLQ QRRQFDGQAI SPYDPKDNST
AVFIAETNEI YTGTVSDFAG NDPLIYRKRL SDDDGLRTQR DDLKVLDSPN FVASFAYGDH
VYFWYREWAA EATDGDRQVY ARVARVCKGD RGGARPAHER WTSFVKARLN CSYPANTPFY
FNELQAVSEP VPVSDGSAVV YAVFTTPESS VRMSAVCAFR MEAIKRVFDY GHFKVQQSAQ
SLWMPFRSHQ MISVPRPGSC VADSSKLPES TVSFITRNPL MHEAVPATRP RPILVQGPER
SELTQIAVVP QIRSVSGAYH NALYLGTSDG RVLKVVDPGD GSTSLIQSAR IFATSVPIVN
LMATYDQLIV VSADEIAAIP LYNCGEQRTC SGCVHLQDAH CAWDLDSARC VGRADGSWTG
GNFVQNVNIG RSEQCPEGAV DPDYYAVDEL HSERATGSEQ QPAQFTTQAL LLAVLITLVV
ASAGGFFVGY RISRWRLLQD GRHHSSGSST GSDYDSYGRA RLTRHDSLTT AKIEHVYGTT
PSKDAVSLVL TMPQNGTALM SSLSNSASGV VTPKISTERN VLASLNNSTL PRDYKVKKVY
L
//
