ID   A0A0B2V6V4_TOXCA        Unreviewed;       775 AA.
AC   A0A0B2V6V4;
DT   04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT   04-MAR-2015, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Krev interaction trapped protein 1 {ECO:0000313|EMBL:KHN77197.1};
GN   Name=KRIT1 {ECO:0000313|EMBL:KHN77197.1};
GN   ORFNames=Tcan_15477 {ECO:0000313|EMBL:KHN77197.1};
OS   Toxocara canis (Canine roundworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Ascaridomorpha; Ascaridoidea; Toxocaridae; Toxocara.
OX   NCBI_TaxID=6265 {ECO:0000313|EMBL:KHN77197.1, ECO:0000313|Proteomes:UP000031036};
RN   [1] {ECO:0000313|EMBL:KHN77197.1, ECO:0000313|Proteomes:UP000031036}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PN_DK_2014 {ECO:0000313|EMBL:KHN77197.1};
RA   Zhu X.-Q., Korhonen P.K., Cai H., Young N.D., Nejsum P.,
RA   von Samson-Himmelstjerna G., Boag P.R., Tan P., Li Q., Min J., Yang Y.,
RA   Wang X., Fang X., Hall R.S., Hofmann A., Sternberg P.W., Jex A.R.,
RA   Gasser R.B.;
RT   "Genetic blueprint of the zoonotic pathogen Toxocara canis.";
RL   Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KHN77197.1}.
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DR   EMBL; JPKZ01002351; KHN77197.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0B2V6V4; -.
DR   STRING; 6265.A0A0B2V6V4; -.
DR   OMA; MKMLEHC; -.
DR   Proteomes; UP000031036; Unassembled WGS sequence.
DR   GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR   CDD; cd14473; FERM_B-lobe; 1.
DR   Gene3D; 1.20.80.10; -; 1.
DR   Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR   Gene3D; 3.30.70.2240; KRIT, N-terminal Nudix domain, NPxY motif-rich region; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   InterPro; IPR019749; Band_41_domain.
DR   InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR   InterPro; IPR035963; FERM_2.
DR   InterPro; IPR019748; FERM_central.
DR   InterPro; IPR000299; FERM_domain.
DR   InterPro; IPR043058; NUDIX_sf.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   PANTHER; PTHR13283; KREV INTERACTION TRAPPED 1-RELATED; 1.
DR   PANTHER; PTHR13283:SF11; KREV INTERACTION TRAPPED PROTEIN 1; 1.
DR   Pfam; PF00023; Ank; 1.
DR   Pfam; PF12796; Ank_2; 1.
DR   Pfam; PF00373; FERM_M; 1.
DR   SMART; SM00248; ANK; 3.
DR   SMART; SM00295; B41; 1.
DR   SUPFAM; SSF48403; Ankyrin repeat; 1.
DR   SUPFAM; SSF47031; Second domain of FERM; 1.
DR   PROSITE; PS50297; ANK_REP_REGION; 1.
DR   PROSITE; PS50088; ANK_REPEAT; 2.
DR   PROSITE; PS50057; FERM_3; 1.
PE   4: Predicted;
KW   ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW   Reference proteome {ECO:0000313|Proteomes:UP000031036}.
FT   REPEAT          370..403
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          404..429
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   DOMAIN          468..775
FT                   /note="FERM"
FT                   /evidence="ECO:0000259|PROSITE:PS50057"
SQ   SEQUENCE   775 AA;  87419 MW;  2F3C24C23CE4FEA9 CRC64;
     MEVSIAIVQL RQTALSEQHN VCTANDYDLL LVNEPSSSSR FSNRLQFPTC RVPHNGQPAE
     LRQTALSEQH NVCTANDYDL LLVNEPSSSS RFSNRLQFPT CRVPHNGQPA EVAFNAARHL
     SARMPRRVVA VPLWENADTA CYTDHLLFPG SPHPIFLCVP LLEKDKNATK STEIGRFENL
     ARVLNCCLTD GETFDVETRH LAFRLEEWLR MEQRRDPRFI STLFVRPISL GRIRSCAHNP
     AYDPEQSMLC HNMMGHGKNA EAQRKSCDLA EEVRRSNDAR ARMIGDEKYD MFIMNPLFGS
     GLHYSNKDNA PSYFAAGRTE RHGSSFSSRK VSGESWPILY PLHKAAYDDN AAEVKRLLAM
     GMTANEVDNA SWTPLHYCAF YNNLKAMEVL LLNTSTDVNI PNKAGSTALH FAALQANAYM
     VELLLSHSAI DVNARDCKGQ RALDVCACVP KAEYQKVAKL LREWNRLDKI QVEMMDGGNA
     QLALVQGQET SAGQLHTEMC KELKLNATSA SLFAIWICSD RLSLQLKADH KPLLHMSKWR
     SKIAKFGNDE NAKSNDDTPK IFFRRDARVA LRTEKATKLT PMALSLLYEE ARCNYLKGLY
     PCSDSDVALL ASIILRIIYG HNYQLTEKML QRIVPKHRIP TSESALKTLM GKIESEHRST
     KANNLIALQQ HFLQICWRFC VYGSTFFDAI VFMNKPMKGS LPVHVGVNDY GLHLINSDSK
     TLFNTYPLKG LQWSIKPDRP YLEVHAGAFG HDFTLRTPQA SHINNLLTRL TGTTK
//