ID A0A0B2V8K3_TOXCA Unreviewed; 318 AA.
AC A0A0B2V8K3;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=DNA-binding protein D-ETS-3 {ECO:0000313|EMBL:KHN77817.1};
GN Name=Ets65A {ECO:0000313|EMBL:KHN77817.1};
GN ORFNames=Tcan_16197 {ECO:0000313|EMBL:KHN77817.1};
OS Toxocara canis (Canine roundworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Ascaridomorpha; Ascaridoidea; Toxocaridae; Toxocara.
OX NCBI_TaxID=6265 {ECO:0000313|EMBL:KHN77817.1, ECO:0000313|Proteomes:UP000031036};
RN [1] {ECO:0000313|EMBL:KHN77817.1, ECO:0000313|Proteomes:UP000031036}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PN_DK_2014 {ECO:0000313|EMBL:KHN77817.1};
RA Zhu X.-Q., Korhonen P.K., Cai H., Young N.D., Nejsum P.,
RA von Samson-Himmelstjerna G., Boag P.R., Tan P., Li Q., Min J., Yang Y.,
RA Wang X., Fang X., Hall R.S., Hofmann A., Sternberg P.W., Jex A.R.,
RA Gasser R.B.;
RT "Genetic blueprint of the zoonotic pathogen Toxocara canis.";
RL Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004019}.
CC -!- SIMILARITY: Belongs to the ETS family. {ECO:0000256|ARBA:ARBA00005562,
CC ECO:0000256|RuleBase:RU004019}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KHN77817.1}.
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DR EMBL; JPKZ01002219; KHN77817.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0B2V8K3; -.
DR STRING; 6265.A0A0B2V8K3; -.
DR OMA; YAESITW; -.
DR Proteomes; UP000031036; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000418; Ets_dom.
DR InterPro; IPR046328; ETS_fam.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11849; ETS; 1.
DR PANTHER; PTHR11849:SF287; TRANSCRIPTION FACTOR AST-1; 1.
DR Pfam; PF00178; Ets; 1.
DR PRINTS; PR00454; ETSDOMAIN.
DR SMART; SM00413; ETS; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00345; ETS_DOMAIN_1; 1.
DR PROSITE; PS00346; ETS_DOMAIN_2; 1.
DR PROSITE; PS50061; ETS_DOMAIN_3; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004019};
KW Nucleus {ECO:0000256|RuleBase:RU004019};
KW Reference proteome {ECO:0000313|Proteomes:UP000031036}.
FT DOMAIN 148..228
FT /note="ETS"
FT /evidence="ECO:0000259|PROSITE:PS50061"
SQ SEQUENCE 318 AA; 35233 MW; DF1625EEB99636B9 CRC64;
MQDAKSDVLP VATPSKEQHQ HNIDLANFNF GAFQLSTNTN VAGAHNMAPM AQRNIFYDQN
STLQMPKQQL GHQSGMNLST NGFHAATPSH SSSSAVVKEE PTTFNSSCFS CPSLRLPTCH
AAPFGQPDPY QILGPTSSRL ASAGSGQIQL WQFLLELLSD SRYAESITWE GTNGEFKLVD
PDDVARRWGE RKSKPNMNYD KMSRALRYYY DKNIMCKVHG KRYAYKFDFQ GIAQALQPQS
NTSSADLFQQ SRLHSSEFIH SPWTAANYRS LMAPQFQASA GALFNPSVGY ASFGSSNNGA
LQARNFPLYA PSNYPKCI
//
