ID   A0A0B2VCV4_TOXCA        Unreviewed;       376 AA.
AC   A0A0B2VCV4;
DT   04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT   04-MAR-2015, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Ribonucleoside-diphosphate reductase small chain {ECO:0000313|EMBL:KHN79237.1};
GN   Name=rnr-2 {ECO:0000313|EMBL:KHN79237.1};
GN   ORFNames=Tcan_11935 {ECO:0000313|EMBL:KHN79237.1};
OS   Toxocara canis (Canine roundworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Ascaridomorpha; Ascaridoidea; Toxocaridae; Toxocara.
OX   NCBI_TaxID=6265 {ECO:0000313|EMBL:KHN79237.1, ECO:0000313|Proteomes:UP000031036};
RN   [1] {ECO:0000313|EMBL:KHN79237.1, ECO:0000313|Proteomes:UP000031036}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PN_DK_2014 {ECO:0000313|EMBL:KHN79237.1};
RA   Zhu X.-Q., Korhonen P.K., Cai H., Young N.D., Nejsum P.,
RA   von Samson-Himmelstjerna G., Boag P.R., Tan P., Li Q., Min J., Yang Y.,
RA   Wang X., Fang X., Hall R.S., Hofmann A., Sternberg P.W., Jex A.R.,
RA   Gasser R.B.;
RT   "Genetic blueprint of the zoonotic pathogen Toxocara canis.";
RL   Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the ribonucleoside diphosphate reductase small
CC       chain family. {ECO:0000256|ARBA:ARBA00009303}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KHN79237.1}.
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DR   EMBL; JPKZ01001930; KHN79237.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0B2VCV4; -.
DR   STRING; 6265.A0A0B2VCV4; -.
DR   OMA; QWINDSQ; -.
DR   Proteomes; UP000031036; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0009263; P:deoxyribonucleotide biosynthetic process; IEA:InterPro.
DR   CDD; cd01049; RNRR2; 1.
DR   Gene3D; 1.10.620.20; Ribonucleotide Reductase, subunit A; 1.
DR   InterPro; IPR009078; Ferritin-like_SF.
DR   InterPro; IPR012348; RNR-like.
DR   InterPro; IPR033909; RNR_small.
DR   InterPro; IPR030475; RNR_small_AS.
DR   InterPro; IPR000358; RNR_small_fam.
DR   PANTHER; PTHR23409; RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SMALL CHAIN; 1.
DR   PANTHER; PTHR23409:SF18; RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SUBUNIT M2; 1.
DR   Pfam; PF00268; Ribonuc_red_sm; 1.
DR   SUPFAM; SSF47240; Ferritin-like; 1.
DR   PROSITE; PS00368; RIBORED_SMALL; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000031036};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        212..233
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   376 AA;  44031 MW;  F6C6222A6839C916 CRC64;
     MHARDFRFKF CGFPYRFHTL VNTIMSTDKF QDDKENMEPE MGSGDASVAV AIDHSDEPLL
     AENPSRFVIF PIKYHDIWTF YKNAVASFWT ADEIDLSHDY ADWERLDDGE RFFISRVLSF
     FAASDGIVNE NLTGRFSTEV QIPEARFFYG FQIMMEGVHS EMYSKMIEAY IKDPKEQMMH
     FDAIHQFECI KKKADWALRW IDDRHSPFPV RLIAFAAVEG IMFSGSFAAI FWLKKRGVMK
     GLTHSNELIS RDEGLHRDFA CLLYKYIKHK PSQEQVYQII KEAVSLEQEY LTEALPVDLI
     GMNCRLMSQY IEYVADHLLT ELGYPKVYNV MNPFDFMENL SIEAKTNFFE RRVSEYQRAG
     VLSPEEEKKF KLDADF
//