ID A0A0B2VEB1_TOXCA Unreviewed; 438 AA.
AC A0A0B2VEB1;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Cytochrome P450 2H1 {ECO:0000313|EMBL:KHN79335.1};
GN Name=CYP2H1 {ECO:0000313|EMBL:KHN79335.1};
GN ORFNames=Tcan_04467 {ECO:0000313|EMBL:KHN79335.1};
OS Toxocara canis (Canine roundworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Ascaridomorpha; Ascaridoidea; Toxocaridae; Toxocara.
OX NCBI_TaxID=6265 {ECO:0000313|EMBL:KHN79335.1, ECO:0000313|Proteomes:UP000031036};
RN [1] {ECO:0000313|EMBL:KHN79335.1, ECO:0000313|Proteomes:UP000031036}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PN_DK_2014 {ECO:0000313|EMBL:KHN79335.1};
RA Zhu X.-Q., Korhonen P.K., Cai H., Young N.D., Nejsum P.,
RA von Samson-Himmelstjerna G., Boag P.R., Tan P., Li Q., Min J., Yang Y.,
RA Wang X., Fang X., Hall R.S., Hofmann A., Sternberg P.W., Jex A.R.,
RA Gasser R.B.;
RT "Genetic blueprint of the zoonotic pathogen Toxocara canis.";
RL Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the cytochrome P450 family.
CC {ECO:0000256|ARBA:ARBA00010617, ECO:0000256|RuleBase:RU000461}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KHN79335.1}.
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DR EMBL; JPKZ01001927; KHN79335.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0B2VEB1; -.
DR STRING; 6265.A0A0B2VEB1; -.
DR OMA; RWHIAYM; -.
DR Proteomes; UP000031036; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR Gene3D; 1.10.630.10; Cytochrome P450; 2.
DR InterPro; IPR001128; Cyt_P450.
DR InterPro; IPR017972; Cyt_P450_CS.
DR InterPro; IPR002401; Cyt_P450_E_grp-I.
DR InterPro; IPR036396; Cyt_P450_sf.
DR PANTHER; PTHR24284; CYTOCHROME P450 FAMILY; 1.
DR PANTHER; PTHR24284:SF1; CYTOCHROME P450 FAMILY; 1.
DR Pfam; PF00067; p450; 2.
DR PRINTS; PR00463; EP450I.
DR PRINTS; PR00385; P450.
DR SUPFAM; SSF48264; Cytochrome P450; 1.
DR PROSITE; PS00086; CYTOCHROME_P450; 1.
PE 3: Inferred from homology;
KW Heme {ECO:0000256|RuleBase:RU000461}; Iron {ECO:0000256|RuleBase:RU000461};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|RuleBase:RU000461};
KW Monooxygenase {ECO:0000256|ARBA:ARBA00023033,
KW ECO:0000256|RuleBase:RU000461};
KW Oxidoreductase {ECO:0000256|RuleBase:RU000461};
KW Reference proteome {ECO:0000313|Proteomes:UP000031036};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..23
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 438 AA; 50008 MW; A4A4B929FBF47E33 CRC64;
MFWVILIIVV FIVLYLAKYY AYIKNYPKGP MPIPLLGNLH QLKTHNTHLH FDELAKAYGD
VFTVFMPRPV VIITKFQNMK KALIRRGDDF VGRSGLFPDN IFQSFPNGGI TFASGDSWRE
QRRISLRILK DFGMGSGITE DQTNFGTEDQ SKKYRLRCGS ADGSVVSSSI KESQQLKDDA
DKLKVFIREQ VDKQKAQFDP CKEPQTFVHA LLLEMHKGNR FLCYEQLVDI TMDFWLAAME
TTSITLRWAI LFLIANPQVQ HRMRAEIIDI VGKDRRICMA DKLSMPYCTV AVVEIQRRAN
VLPQNVMHRT VKQTMVSGHC IPADTLVLPQ ISSVLSDSSL FENPDEFKPE RFLQDDGKTP
HKELLQYVVP FSMGKRQCAG EPLASVKLFL ILTTLLQNFI LEKPLDGALP DLEPDFAFFA
FPKQYKLRIV PISGCEES
//
