ID A0A0B2VM37_TOXCA Unreviewed; 992 AA.
AC A0A0B2VM37;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Sulfate permease family protein 3 {ECO:0000313|EMBL:KHN82502.1};
GN Name=sulp-3 {ECO:0000313|EMBL:KHN82502.1};
GN ORFNames=Tcan_04963 {ECO:0000313|EMBL:KHN82502.1};
OS Toxocara canis (Canine roundworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Ascaridomorpha; Ascaridoidea; Toxocaridae; Toxocara.
OX NCBI_TaxID=6265 {ECO:0000313|EMBL:KHN82502.1, ECO:0000313|Proteomes:UP000031036};
RN [1] {ECO:0000313|EMBL:KHN82502.1, ECO:0000313|Proteomes:UP000031036}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PN_DK_2014 {ECO:0000313|EMBL:KHN82502.1};
RA Zhu X.-Q., Korhonen P.K., Cai H., Young N.D., Nejsum P.,
RA von Samson-Himmelstjerna G., Boag P.R., Tan P., Li Q., Min J., Yang Y.,
RA Wang X., Fang X., Hall R.S., Hofmann A., Sternberg P.W., Jex A.R.,
RA Gasser R.B.;
RT "Genetic blueprint of the zoonotic pathogen Toxocara canis.";
RL Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU362052}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU362052}.
CC -!- SIMILARITY: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
CC {ECO:0000256|RuleBase:RU362052}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KHN82502.1}.
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DR EMBL; JPKZ01001346; KHN82502.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0B2VM37; -.
DR STRING; 6265.A0A0B2VM37; -.
DR OMA; VKIPGVM; -.
DR Proteomes; UP000031036; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008509; F:monoatomic anion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0008271; F:secondary active sulfate transmembrane transporter activity; IEA:InterPro.
DR CDD; cd07042; STAS_SulP_like_sulfate_transporter; 1.
DR Gene3D; 3.30.750.24; STAS domain; 1.
DR InterPro; IPR018045; S04_transporter_CS.
DR InterPro; IPR011547; SLC26A/SulP_dom.
DR InterPro; IPR001902; SLC26A/SulP_fam.
DR InterPro; IPR002645; STAS_dom.
DR InterPro; IPR036513; STAS_dom_sf.
DR PANTHER; PTHR11814:SF233; ANION TRANSPORTER SULP-4; 1.
DR PANTHER; PTHR11814; SULFATE TRANSPORTER; 1.
DR Pfam; PF01740; STAS; 1.
DR Pfam; PF00916; Sulfate_transp; 1.
DR SUPFAM; SSF52091; SpoIIaa-like; 1.
DR PROSITE; PS01130; SLC26A; 1.
DR PROSITE; PS50801; STAS; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362052};
KW Reference proteome {ECO:0000313|Proteomes:UP000031036};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362052};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362052}; Transport {ECO:0000256|RuleBase:RU362052}.
FT TRANSMEM 65..90
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 102..122
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 129..146
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 206..226
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 289..308
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 320..339
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 367..387
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 407..426
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 446..464
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 540..559
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 571..593
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 622..640
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 660..681
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 693..711
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 744..761
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 767..784
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT DOMAIN 808..961
FT /note="STAS"
FT /evidence="ECO:0000259|PROSITE:PS50801"
SQ SEQUENCE 992 AA; 110847 MW; C772EF3B08E83403 CRC64;
MYYFTIDEER RALVGMSEDA NGPDISPTGS TRRAMNQEEF DAQFTYRAPE ESLTRSRLKK
FLRRYYQPCL SVNGFFNAVI GFIPIIGWLP KYSFRDNFIT DVIGGLTVGI MHVPQGIAYA
SLARVDPVVG LYTSFFPPLL YMIFGTSRHN SIGSFAVVSL MAGLAADRLV SEYNSQRLPI
HKELLELANN ETGLPDELHP LSHIEVVSVL TLAIGLVNIL MGMLHLEFIT TYFSDQVVSG
FSTAASMHVF VAQLKDVFSI RGLPKRTGFG QLFLRVFDII SHITSSNPYT IIIAVLSTVF
LLVGKEIVGP FAKKKLRLPV PIPFELILVI IATILSSSFD AYHRYNVSIV NRIPTGLPVP
KLPRFDLIPQ LVGDAFGIAA VIVAVHISLA KMFAKKLDYE IDPGQELYAI GFASAASSFF
PVYPMACSLG RTLVNVEAGT KTQLSALFSS ALLFAVILFF GQYLKTLPMI LMGMLHLEFI
TTYFSDQVVS GFSTAASMHV FVAQLKDVFS IRGLPKRTGF GQLFLRVFDI ISHITSSNPY
TIIIAVLSTV FLLVGKEIVG PFAKKKLRLP VPIPFELILV IIATILSSSF DAYHRYNVSI
VNRIPTGLPV PKLPRFDLIP QLVGDAFGIA AVIVAVHISL AKMFAKKLDY EIDPGQELYA
IGFASAASSF FPVYPMACSL GRTLVNVEAG TKTQLSALFS SALLFAVILF FGQYLKTLPM
CVLSAIIIVA LKGMFKKFGE LKRLWILSTI DFLIWLVSFV ATVGYDVMQG LVISIGFALM
TTVFRTQWSR WHLLANLEGT NDFRDSERYH SVTTYSGICV LRFDSPLLFT NVERFKRVVY
KVLKEWRAAR PSVYHPHDYQ IDDLTKHIKK GSRVLPEDKE NPLAIRLSRH FVIDCSGFTF
VDFMGVNALK EIFAEMRSQK VLVYFAAAKA PVRELFESSG FYRFVPKENF YPTIRDAVII
ARQRQASSSL PSQHSELYHD PVEEMHHTQP LH
//
