ID   A0A0B2VPE1_TOXCA        Unreviewed;       928 AA.
AC   A0A0B2VPE1;
DT   04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT   04-MAR-2015, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=Alsin {ECO:0000313|EMBL:KHN82905.1};
GN   Name=ALS2 {ECO:0000313|EMBL:KHN82905.1};
GN   ORFNames=Tcan_14241 {ECO:0000313|EMBL:KHN82905.1};
OS   Toxocara canis (Canine roundworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Ascaridomorpha; Ascaridoidea; Toxocaridae; Toxocara.
OX   NCBI_TaxID=6265 {ECO:0000313|EMBL:KHN82905.1, ECO:0000313|Proteomes:UP000031036};
RN   [1] {ECO:0000313|EMBL:KHN82905.1, ECO:0000313|Proteomes:UP000031036}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PN_DK_2014 {ECO:0000313|EMBL:KHN82905.1};
RA   Zhu X.-Q., Korhonen P.K., Cai H., Young N.D., Nejsum P.,
RA   von Samson-Himmelstjerna G., Boag P.R., Tan P., Li Q., Min J., Yang Y.,
RA   Wang X., Fang X., Hall R.S., Hofmann A., Sternberg P.W., Jex A.R.,
RA   Gasser R.B.;
RT   "Genetic blueprint of the zoonotic pathogen Toxocara canis.";
RL   Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KHN82905.1}.
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DR   EMBL; JPKZ01001280; KHN82905.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0B2VPE1; -.
DR   STRING; 6265.A0A0B2VPE1; -.
DR   Proteomes; UP000031036; Unassembled WGS sequence.
DR   Gene3D; 2.130.10.30; Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II; 3.
DR   InterPro; IPR009091; RCC1/BLIP-II.
DR   InterPro; IPR000408; Reg_chr_condens.
DR   PANTHER; PTHR46089:SF1; ALS2 C-TERMINAL-LIKE PROTEIN; 1.
DR   PANTHER; PTHR46089; ALSIN HOMOLOG; 1.
DR   Pfam; PF00415; RCC1; 2.
DR   PRINTS; PR00633; RCCNDNSATION.
DR   SUPFAM; SSF50985; RCC1/BLIP-II; 3.
DR   PROSITE; PS00626; RCC1_2; 2.
DR   PROSITE; PS50012; RCC1_3; 3.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000031036};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           22..928
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5002080268"
FT   REPEAT          417..468
FT                   /note="RCC1"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT   REPEAT          651..702
FT                   /note="RCC1"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT   REPEAT          703..754
FT                   /note="RCC1"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT   REGION          298..339
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          380..411
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          532..573
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          614..644
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        298..319
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        320..334
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        380..403
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        532..553
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        554..568
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        614..637
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   928 AA;  101313 MW;  B8E8A48C37E7E6AE CRC64;
     MGLEWTTFVS FLMRLIWTST GQRKELASNE TSWSRLVDDI TTTLNSFVYF NGTRFCLVDG
     KIFRILPNGS TAPFLSVDSP LLSSRFSYIN ASGGTFFAVS EEGRLYARGK SNYGQCGVVL
     EDEIAEFREV KLIAPLAVCP HGTTVTSHEP ICVCQVAASQ NLVCIVDDEG HLWSYGGQSL
     KFSSNGCIEA KLMPLSRGRK VLQIEAGMAH FVSLVASYAE EDGKGVELDT QSLHRSILPS
     RQCEQCREED ELRLSTLMER ADRDAAQERC GLEDLVKCDE EASENLISAA RNLRLQFRTD
     SSQSSPRAKT LPLQNDFHSS RKSRTVRREN TEGGEIEMST IGPPIGLELM NLPGGHFTFV
     SLNNLPLTYM DSGNESCSNT DCTTSTCSSS RRSAASSPRK NGTSDVMGGR DDKRAPLEVW
     TWGANNFGQL GHNDLIARRE PFRVSALSGI CCVKVSAGDN HTAVLTATGE MYVWGSNKCG
     QLKQSDQSYL TAPSLFRDAA QERCGLEDLV KCDEEASENL ISAARNLRLQ FRTDSSQSSP
     RAKTLPLQND FHSSRKSRTV RRENTEGGEI EMSTIGPPIG LELMNLPGGH FTFVSLNNLP
     LTYMDSGNES CSNTDCTTST CSSSRRSAAS SPRKNGTSDV MGGRDDKRAP LEVWTWGANN
     FGQLGHNDLI ARREPFRVSA LSGICCVKVS AGDNHTAVLT ATGEMYVWGS NKCGQLKQSD
     QSYLTAPSLF RVGSQSSVLD VSASVSQTAV IVSGIDATPT VYLCGQNAQT SFLHPQTFRI
     SSVEKIGLPS CVRLLGSELV LGMYGRDDLL DETGVALFSF VFSRLKFAKF ARELADLCQM
     LHERSHIVGE SEMSTLLNRL TLSSCAFAVQ AARLAESCRT VLTQKGDASI CSILEAAMSL
     PFMDSLYTFH ADFVDCIAFG CFADIDLG
//