ID   A0A0B2VV98_TOXCA        Unreviewed;       524 AA.
AC   A0A0B2VV98;
DT   04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT   04-MAR-2015, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Ovochymase-1 {ECO:0000313|EMBL:KHN85608.1};
GN   Name=OVCH1 {ECO:0000313|EMBL:KHN85608.1};
GN   ORFNames=Tcan_13450 {ECO:0000313|EMBL:KHN85608.1};
OS   Toxocara canis (Canine roundworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Ascaridomorpha; Ascaridoidea; Toxocaridae; Toxocara.
OX   NCBI_TaxID=6265 {ECO:0000313|EMBL:KHN85608.1, ECO:0000313|Proteomes:UP000031036};
RN   [1] {ECO:0000313|EMBL:KHN85608.1, ECO:0000313|Proteomes:UP000031036}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PN_DK_2014 {ECO:0000313|EMBL:KHN85608.1};
RA   Zhu X.-Q., Korhonen P.K., Cai H., Young N.D., Nejsum P.,
RA   von Samson-Himmelstjerna G., Boag P.R., Tan P., Li Q., Min J., Yang Y.,
RA   Wang X., Fang X., Hall R.S., Hofmann A., Sternberg P.W., Jex A.R.,
RA   Gasser R.B.;
RT   "Genetic blueprint of the zoonotic pathogen Toxocara canis.";
RL   Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KHN85608.1}.
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DR   EMBL; JPKZ01000755; KHN85608.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0B2VV98; -.
DR   STRING; 6265.A0A0B2VV98; -.
DR   Proteomes; UP000031036; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   Gene3D; 2.40.10.10; Trypsin-like serine proteases; 2.
DR   InterPro; IPR009003; Peptidase_S1_PA.
DR   InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR   InterPro; IPR001254; Trypsin_dom.
DR   InterPro; IPR018114; TRYPSIN_HIS.
DR   PANTHER; PTHR24260; -; 1.
DR   PANTHER; PTHR24260:SF136; PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00089; Trypsin; 2.
DR   SMART; SM00020; Tryp_SPc; 1.
DR   SUPFAM; SSF50494; Trypsin-like serine proteases; 2.
DR   PROSITE; PS50240; TRYPSIN_DOM; 1.
DR   PROSITE; PS00134; TRYPSIN_HIS; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000031036};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        9..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          65..464
FT                   /note="Peptidase S1"
FT                   /evidence="ECO:0000259|PROSITE:PS50240"
SQ   SEQUENCE   524 AA;  58596 MW;  6747ADD38F6D1AD8 CRC64;
     MRCKVQRQPF LLLLVGISML ITYYRLSRVE QQHPEIVHRL TADELRELHT ICGRASSYSS
     PKYRIAGGNR AAENQFPWAV RLFIKAADLP FFMSLSCTAS LISRWHIVTA AHCIQYTDLG
     VRDVNVSTHF VAVAGTTCAH HELVGGKKCY DAATKQGTIL RIKSVLIAEN AIRHQVIQSM
     AWGKLRERVP IELADFALLE LDKPIDVNNT DIRPICLHPP NQPSSSLYTL YGFGLTDIAY
     NKSTSGQLHY FETNSTVSEN RCRTIPDITI RENCNRLIVM MRNATTKTSA CKVIQSMAWG
     KLRERVPIEL ADFALLELDK PIDVNNTDIR PICLHPPNQP SSSLYTLYGF GLTDIAYNKS
     TSGQLHYFET NSTVSENRCR TIPDITIREN CKRLIVMMRN ATTKTSACKG DSGGGVSMRK
     GRTHFLVGVI STGIGHCTLA DPSLLATLGY MDVSVKLSSY HDFICFHTGI CPMGYNRYMS
     SHPQRAFVLR SNTGKYSIGN GTVQVNSKLD VDCSKKHSQY SQKL
//