ID A0A0B2W0L6_TOXCA Unreviewed; 833 AA.
AC A0A0B2W0L6;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=CCR4-NOT transcription complex subunit 4 {ECO:0000313|EMBL:KHN87508.1};
GN Name=CNOT4 {ECO:0000313|EMBL:KHN87508.1};
GN ORFNames=Tcan_15404 {ECO:0000313|EMBL:KHN87508.1};
OS Toxocara canis (Canine roundworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Ascaridomorpha; Ascaridoidea; Toxocaridae; Toxocara.
OX NCBI_TaxID=6265 {ECO:0000313|EMBL:KHN87508.1, ECO:0000313|Proteomes:UP000031036};
RN [1] {ECO:0000313|EMBL:KHN87508.1, ECO:0000313|Proteomes:UP000031036}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PN_DK_2014 {ECO:0000313|EMBL:KHN87508.1};
RA Zhu X.-Q., Korhonen P.K., Cai H., Young N.D., Nejsum P.,
RA von Samson-Himmelstjerna G., Boag P.R., Tan P., Li Q., Min J., Yang Y.,
RA Wang X., Fang X., Hall R.S., Hofmann A., Sternberg P.W., Jex A.R.,
RA Gasser R.B.;
RT "Genetic blueprint of the zoonotic pathogen Toxocara canis.";
RL Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KHN87508.1}.
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DR EMBL; JPKZ01000421; KHN87508.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0B2W0L6; -.
DR STRING; 6265.A0A0B2W0L6; -.
DR OMA; YARYEDA; -.
DR Proteomes; UP000031036; Unassembled WGS sequence.
DR GO; GO:0030014; C:CCR4-NOT complex; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR CDD; cd16618; mRING-HC-C4C4_CNOT4; 1.
DR CDD; cd12438; RRM_CNOT4; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR034261; CNOT4_RRM.
DR InterPro; IPR039780; Mot2.
DR InterPro; IPR039515; NOT4_mRING-HC-C4C4.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR003954; RRM_dom_euk.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR12603; CCR4-NOT TRANSCRIPTION COMPLEX RELATED; 1.
DR PANTHER; PTHR12603:SF0; CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 4; 1.
DR Pfam; PF00076; RRM_1; 1.
DR Pfam; PF14570; zf-RING_4; 1.
DR SMART; SM00361; RRM_1; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS50102; RRM; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}; Reference proteome {ECO:0000313|Proteomes:UP000031036};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 11..54
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 106..190
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 256..393
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 428..458
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 632..700
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 763..801
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 269..300
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 301..331
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 345..361
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 362..387
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 632..649
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 661..683
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 833 AA; 91696 MW; 6B5BF857C4A88749 CRC64;
MSSDEQSEKE CPLCMEPLEI DDIDFYPCKC EYQICRFCWH RLRTDENGLC PACRQPYPEN
PVNFKPLSAS DVLKIKSEKK QKQQQQRIKM SESRKHLSSY RVLQKNLVYV VGLSARVADP
DILKKPEYFG KYGRILKVAV GSSASSNGPQ SASCTAYVTY ARYEDALRAI QAVNNAQLDG
RIVKASLGTT KYCSSFLRSQ PCHKPECMYL HDVADNEVSF TKDDMHLGRH AEYEKKLIET
TLLKDKAQRE RVYLIANNRR KHSQSKSGER AASVHTTSAS FAAEKSLEKT TNFNSRQTDR
SGSRSRSDTI PCREKSEHST REMERPVDSN SKHVKGTSPP DENSKPAVKC EKRDEQPESE
NTCKRTLPSQ ENRAPIGQQS QHLKGDGDSH NSAPLRSRLV QWTSPERILH EKIDASSDTM
QKVLRNGVDG ENKNSSCDIE HRDDGVSTQV NGSADPSSTC DWQRALGLSM TDGTLESSQG
EVVASAPATV QQQQIRRPSR LSAHSDDELA GKVFSGFDPF SESAKGLADL LEEEKSRPPR
FDPFSESAKG LADLLEEEKS RPPRFPQSSA SMPSVTSSLM SLGMQCGWPS AGALNGGYEC
GAFGSRVDAV PHSNYFVSTT ISPSEYFGSM SMTAAGQPPL QHNPNPSSFY ISPQQPPPQR
PSASSYTSQH QPTLAQKSPQ LNGRSVVPPY PDPPPGLSSI YHQQRYSSFV PVSTPQALPH
ANHSPTSADA AQLNEWQEGL KALLPNVNVR FVSELNAAGY PTTRGQVSSA QQQHSSQPQT
SMLGCYGQGG SSSPSQMPSS LGAPLSMLSM NSFAQPVPQW MPPPPGFSHI SKR
//
