ID A0A0B2W3E9_TOXCA Unreviewed; 734 AA.
AC A0A0B2W3E9;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 08-NOV-2023, entry version 27.
DE RecName: Full=Nucleolar protein 10 {ECO:0000256|ARBA:ARBA00015517};
GN Name=nol10 {ECO:0000313|EMBL:KHN87705.1};
GN ORFNames=Tcan_03918 {ECO:0000313|EMBL:KHN87705.1};
OS Toxocara canis (Canine roundworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Ascaridomorpha; Ascaridoidea; Toxocaridae; Toxocara.
OX NCBI_TaxID=6265 {ECO:0000313|EMBL:KHN87705.1, ECO:0000313|Proteomes:UP000031036};
RN [1] {ECO:0000313|EMBL:KHN87705.1, ECO:0000313|Proteomes:UP000031036}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PN_DK_2014 {ECO:0000313|EMBL:KHN87705.1};
RA Zhu X.-Q., Korhonen P.K., Cai H., Young N.D., Nejsum P.,
RA von Samson-Himmelstjerna G., Boag P.R., Tan P., Li Q., Min J., Yang Y.,
RA Wang X., Fang X., Hall R.S., Hofmann A., Sternberg P.W., Jex A.R.,
RA Gasser R.B.;
RT "Genetic blueprint of the zoonotic pathogen Toxocara canis.";
RL Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
CC -!- SIMILARITY: Belongs to the WD repeat NOL10/ENP2 family.
CC {ECO:0000256|ARBA:ARBA00005264}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KHN87705.1}.
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DR EMBL; JPKZ01000350; KHN87705.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0B2W3E9; -.
DR STRING; 6265.A0A0B2W3E9; -.
DR OMA; CFDSEVT; -.
DR Proteomes; UP000031036; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR040382; NOL10/Enp2.
DR InterPro; IPR012580; NUC153.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR14927:SF0; NUCLEOLAR PROTEIN 10; 1.
DR PANTHER; PTHR14927; UNCHARACTERIZED; 1.
DR Pfam; PF08159; NUC153; 1.
DR SMART; SM00320; WD40; 3.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000031036};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574}.
FT DOMAIN 489..515
FT /note="NUC153"
FT /evidence="ECO:0000259|Pfam:PF08159"
FT REGION 528..650
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 563..590
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 591..623
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 631..650
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 734 AA; 84091 MW; F3307D214BEEFA01 CRC64;
MQLSIANDVK IYNLSAGKSI PEWISERKRR KLEQKDIDIR RRIQLIQDFD MPDVSHTVDI
SPDGRYVFAT GTYKPFVKCF DLNDISLKFS RGLDADVIKM VVLSDDYSKF VLLEEDRYIE
MHAAFGRYFR MRIPKFGRDM AFCREASDLF IVGSSSEIYR LNLEQGQFLE PLVTSSSSLT
CCEFNDDHQL FVCGTIDARV EAWDHRDRSR AGILDCAPYA FLDDFTNELP QASTVKFKDA
LHLAVGTTTG KILLYDIRSS RPLLVKDHQM GLPVRKIEFV ADHDLVLSMD SRVLKMWNEK
DGKPFAAIEP GTGLADFCRY PDSGLLLFAN EAPKMLQYFV PAIGTAPKWC SYLETITEEL
EETEQPAVYD DYKFVTSQQL EDVGLSHLIG TNILRAYMHG YFIDVRLYNK AKTFTQPFAY
DNYKQRKLLE KMDDERANLS VIKKNEEKKV PKVNKELAAK LQAEISLLDE RVDKRSKKKG
KEASTVLADQ RFASLFTNPD FEIDQESEQY KLINPALKKL EEKKKRLARK RNDQTSSGED
DEEYAVQSGL FMEEKPKEDS SSDSSSEDEE LGQADSEESD EDEHEIDQAK GQEEDDESGK
ERRTKKQEME GRKARKPKGF QLIELDVGED ASQFMTQSSD AQKGSSQTLG AMREQLSENV
ADAERTNAPF GGRQMTFRIK PRGAAAYAQR IAEKQEEHLK ERKELHRGAR EITRTLKRLP
VRGGFRGRGR PHRH
//
