ID   A0A0B2W6A0_TOXCA        Unreviewed;       396 AA.
AC   A0A0B2W6A0;
DT   04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT   04-MAR-2015, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   SubName: Full=Nuclear hormone receptor E75 {ECO:0000313|EMBL:KHN89107.1};
GN   Name=E75 {ECO:0000313|EMBL:KHN89107.1};
GN   ORFNames=Tcan_18126 {ECO:0000313|EMBL:KHN89107.1};
OS   Toxocara canis (Canine roundworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Ascaridomorpha; Ascaridoidea; Toxocaridae; Toxocara.
OX   NCBI_TaxID=6265 {ECO:0000313|EMBL:KHN89107.1, ECO:0000313|Proteomes:UP000031036};
RN   [1] {ECO:0000313|EMBL:KHN89107.1, ECO:0000313|Proteomes:UP000031036}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PN_DK_2014 {ECO:0000313|EMBL:KHN89107.1};
RA   Zhu X.-Q., Korhonen P.K., Cai H., Young N.D., Nejsum P.,
RA   von Samson-Himmelstjerna G., Boag P.R., Tan P., Li Q., Min J., Yang Y.,
RA   Wang X., Fang X., Hall R.S., Hofmann A., Sternberg P.W., Jex A.R.,
RA   Gasser R.B.;
RT   "Genetic blueprint of the zoonotic pathogen Toxocara canis.";
RL   Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KHN89107.1}.
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DR   EMBL; JPKZ01000044; KHN89107.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0B2W6A0; -.
DR   STRING; 6265.A0A0B2W6A0; -.
DR   Proteomes; UP000031036; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.565.10; Retinoid X Receptor; 1.
DR   InterPro; IPR035500; NHR-like_dom_sf.
DR   InterPro; IPR000536; Nucl_hrmn_rcpt_lig-bd.
DR   InterPro; IPR001723; Nuclear_hrmn_rcpt.
DR   PANTHER; PTHR24082; NUCLEAR HORMONE RECEPTOR; 1.
DR   PANTHER; PTHR24082:SF334; NUCLEAR HORMONE RECEPTOR FAMILY MEMBER NHR-85; 1.
DR   Pfam; PF00104; Hormone_recep; 1.
DR   PRINTS; PR00398; STRDHORMONER.
DR   SMART; SM00430; HOLI; 1.
DR   SUPFAM; SSF48508; Nuclear receptor ligand-binding domain; 1.
DR   PROSITE; PS51843; NR_LBD; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:KHN89107.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000031036};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT   DOMAIN          85..293
FT                   /note="NR LBD"
FT                   /evidence="ECO:0000259|PROSITE:PS51843"
SQ   SEQUENCE   396 AA;  44021 MW;  D6D86817FE85D6B9 CRC64;
     MLMRVCAPIH FKLKAWSRDK QYNGFHIVNF STWRAVRFGR VPKREKARLV EEMARASARS
     LVDALCAELE DERAVLEACD VAFATLAHSV NTYANSNNYQ TDLRCPLRSS GYLPTLKAVV
     EFSTSIPGFH LIFQQDRVQL LKGSVFQAVL LAMLPARFCA SVASSFMMTG RVSGESGHFF
     TDSLIDFVQR FRQLALSERQ LGLLCALAIC HPEGISLQQP SLAHALYERL CWLLHSVLLA
     SPGSASAQLV LTALTDLRTL HTLHQEKLQA IRFAPISDSQ SVCSSVASSC DEGITCPKVD
     VSDACLPRLD TPVLPSDASH QHRRYLCASV GMRETFYDSH RERALSFVDR HRAIATLLEK
     PPSRCAPTAH LRSTSFTCEI LPCDEQPLNL SVKKSL
//