ID A0A0B2WCZ6_METAS Unreviewed; 329 AA.
AC A0A0B2WCZ6;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Polyketide synthase {ECO:0000313|EMBL:KHN93701.1};
GN ORFNames=MAM_08438 {ECO:0000313|EMBL:KHN93701.1};
OS Metarhizium album (strain ARSEF 1941).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Clavicipitaceae; Metarhizium.
OX NCBI_TaxID=1081103 {ECO:0000313|EMBL:KHN93701.1, ECO:0000313|Proteomes:UP000030816};
RN [1] {ECO:0000313|EMBL:KHN93701.1, ECO:0000313|Proteomes:UP000030816}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ARSEF 1941 {ECO:0000313|EMBL:KHN93701.1,
RC ECO:0000313|Proteomes:UP000030816};
RX PubMed=25368161; DOI=10.1073/pnas.1412662111;
RA Hu X., Xiao G., Zheng P., Shang Y., Su Y., Zhang X., Liu X., Zhan S.,
RA St Leger R.J., Wang C.;
RT "Trajectory and genomic determinants of fungal-pathogen speciation and host
RT adaptation.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:16796-16801(2014).
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP
CC synthases family. {ECO:0000256|RuleBase:RU003694}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KHN93701.1}.
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DR EMBL; AZHE01000067; KHN93701.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0B2WCZ6; -.
DR STRING; 1081103.A0A0B2WCZ6; -.
DR HOGENOM; CLU_000022_16_2_1; -.
DR OrthoDB; 5396558at2759; -.
DR Proteomes; UP000030816; Unassembled WGS sequence.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR CDD; cd00833; PKS; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR018201; Ketoacyl_synth_AS.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR43775; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR43775:SF21; NON-REDUCING POLYKETIDE SYNTHASE AUSA-RELATED; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00606; KS3_1; 1.
DR PROSITE; PS52004; KS3_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000030816};
KW Transferase {ECO:0000256|RuleBase:RU003694}.
FT DOMAIN 11..329
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
SQ SEQUENCE 329 AA; 35201 MW; 2F27814822E6E17F CRC64;
MNGDIRSEYP SHAVAVVGMA GRFPGAKSVD ALWDLLEAGK STVEPAPTER IGLRHLPPDD
LSRMWWGNFL DDVDAFDHEF FRITAREAQT WDPQQRIMLE VAYEALEDGG QFGASLPSRN
RDFGCYIGAV MNNYYDNVAC HKASAYATKG TSRCYISGAV SHFFGWTGPA ITLDTACSSS
MVAVHAACKA IIAGECSRAI AGGTNVITSP HDYRNLAAAG FLSPTGQCKP FDSDADGYCR
AEGVGVVVLK SLATAIEEND RVLGVIVGSA VSQSGNVGHI AVPDTRAQVL LHRKALSIAK
LSPEEVSYVE AHGTGTKLMA CRQISRPSL
//
