ID A0A0B2WLP4_METAS Unreviewed; 458 AA.
AC A0A0B2WLP4;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 13-SEP-2023, entry version 30.
DE RecName: Full=ethanolamine-phosphate cytidylyltransferase {ECO:0000256|ARBA:ARBA00024221};
DE EC=2.7.7.14 {ECO:0000256|ARBA:ARBA00024221};
DE AltName: Full=CTP:phosphoethanolamine cytidylyltransferase {ECO:0000256|ARBA:ARBA00031473};
GN ORFNames=MAM_07267 {ECO:0000313|EMBL:KHN94848.1};
OS Metarhizium album (strain ARSEF 1941).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Clavicipitaceae; Metarhizium.
OX NCBI_TaxID=1081103 {ECO:0000313|EMBL:KHN94848.1, ECO:0000313|Proteomes:UP000030816};
RN [1] {ECO:0000313|EMBL:KHN94848.1, ECO:0000313|Proteomes:UP000030816}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ARSEF 1941 {ECO:0000313|EMBL:KHN94848.1,
RC ECO:0000313|Proteomes:UP000030816};
RX PubMed=25368161; DOI=10.1073/pnas.1412662111;
RA Hu X., Xiao G., Zheng P., Shang Y., Su Y., Zhang X., Liu X., Zhan S.,
RA St Leger R.J., Wang C.;
RT "Trajectory and genomic determinants of fungal-pathogen speciation and host
RT adaptation.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:16796-16801(2014).
CC -!- PATHWAY: Lipid metabolism. {ECO:0000256|ARBA:ARBA00005189}.
CC -!- PATHWAY: Phospholipid metabolism; phosphatidylethanolamine
CC biosynthesis; phosphatidylethanolamine from ethanolamine: step 2/3.
CC {ECO:0000256|ARBA:ARBA00024191}.
CC -!- SIMILARITY: Belongs to the cytidylyltransferase family.
CC {ECO:0000256|ARBA:ARBA00010101}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KHN94848.1}.
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DR EMBL; AZHE01000029; KHN94848.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0B2WLP4; -.
DR STRING; 1081103.A0A0B2WLP4; -.
DR HOGENOM; CLU_031246_0_0_1; -.
DR OrthoDB; 5474784at2759; -.
DR UniPathway; UPA00558; UER00742.
DR Proteomes; UP000030816; Unassembled WGS sequence.
DR GO; GO:0004306; F:ethanolamine-phosphate cytidylyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0006646; P:phosphatidylethanolamine biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd02174; CCT; 1.
DR Gene3D; 3.40.50.620; HUPs; 2.
DR InterPro; IPR041723; CCT.
DR InterPro; IPR004821; Cyt_trans-like.
DR InterPro; IPR044608; Ect1/PCYT2.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR NCBIfam; TIGR00125; cyt_tran_rel; 1.
DR PANTHER; PTHR45780; ETHANOLAMINE-PHOSPHATE CYTIDYLYLTRANSFERASE; 1.
DR PANTHER; PTHR45780:SF2; ETHANOLAMINE-PHOSPHATE CYTIDYLYLTRANSFERASE; 1.
DR Pfam; PF01467; CTP_transf_like; 1.
DR SUPFAM; SSF52374; Nucleotidylyl transferase; 2.
PE 3: Inferred from homology;
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Phospholipid biosynthesis {ECO:0000256|ARBA:ARBA00023209};
KW Phospholipid metabolism {ECO:0000256|ARBA:ARBA00023264};
KW Reference proteome {ECO:0000313|Proteomes:UP000030816};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 27..150
FT /note="Cytidyltransferase-like"
FT /evidence="ECO:0000259|Pfam:PF01467"
FT REGION 434..458
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 458 AA; 50720 MW; 8616722973C8FDA7 CRC64;
MSMSAATEEG QPQGEPAPEL LDGRIWVDGC WDFFHHGHAG AMVQARQLGD ELYVGVHSDE
EILANKGPTV MTLEERLAAA NACRWVTKAI GHAPYVTELP YITHYGCKYV VHGDDITSDG
DGNDCYRFVK QAGRFKVVRR APGISTTDLV GRMLLCTKTH FIHSLQEMLV GEEGYGSPDE
RKAQGKTMLE RMKLYATNET AKAPGADVWF WNASNQAKAG DTEEETGTFE KLLTGIGPRP
GQRIVYVDGG FDLFSSGHIE FLRRVVVEEA KVAGKSDWYS DEAKSKRTSN GGKDYDPAFV
VVGVHDDEVI NQWKGVNYPI MNIFERGLCV LQCKYINAVV FGAPFTPTES YLKSMPWGVP
DAIYHGPTAF MPLTYDPYTA TKKMGIYREI GQHAFAEVNA GEIVQRIMKS RDRYEARQRA
KGVKAEVEAA ARQREILEEE QRSREASTGA GDAVGPNA
//
