ID   A0A0B2WV07_METAS        Unreviewed;       584 AA.
AC   A0A0B2WV07;
DT   04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT   04-MAR-2015, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   RecName: Full=COP9 signalosome complex subunit 4 {ECO:0000256|ARBA:ARBA00014881};
GN   ORFNames=MAM_01860 {ECO:0000313|EMBL:KHN99936.1};
OS   Metarhizium album (strain ARSEF 1941).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Clavicipitaceae; Metarhizium.
OX   NCBI_TaxID=1081103 {ECO:0000313|EMBL:KHN99936.1, ECO:0000313|Proteomes:UP000030816};
RN   [1] {ECO:0000313|EMBL:KHN99936.1, ECO:0000313|Proteomes:UP000030816}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ARSEF 1941 {ECO:0000313|EMBL:KHN99936.1,
RC   ECO:0000313|Proteomes:UP000030816};
RX   PubMed=25368161; DOI=10.1073/pnas.1412662111;
RA   Hu X., Xiao G., Zheng P., Shang Y., Su Y., Zhang X., Liu X., Zhan S.,
RA   St Leger R.J., Wang C.;
RT   "Trajectory and genomic determinants of fungal-pathogen speciation and host
RT   adaptation.";
RL   Proc. Natl. Acad. Sci. U.S.A. 111:16796-16801(2014).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC       Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the CSN4 family.
CC       {ECO:0000256|ARBA:ARBA00010417}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KHN99936.1}.
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DR   EMBL; AZHE01000003; KHN99936.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0B2WV07; -.
DR   STRING; 1081103.A0A0B2WV07; -.
DR   HOGENOM; CLU_466978_0_0_1; -.
DR   OrthoDB; 5476188at2759; -.
DR   Proteomes; UP000030816; Unassembled WGS sequence.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR000717; PCI_dom.
DR   InterPro; IPR040134; PSMD12/CSN4.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR10855; 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12/COP9 SIGNALOSOME COMPLEX SUBUNIT 4; 1.
DR   PANTHER; PTHR10855:SF2; COP9 SIGNALOSOME COMPLEX SUBUNIT 4; 1.
DR   Pfam; PF01399; PCI; 1.
DR   Pfam; PF02466; Tim17; 1.
DR   SMART; SM00088; PINT; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50250; PCI; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000030816}.
FT   DOMAIN          363..532
FT                   /note="PCI"
FT                   /evidence="ECO:0000259|PROSITE:PS50250"
SQ   SEQUENCE   584 AA;  64334 MW;  5E5F4B907759B7DE CRC64;
     MATSIQLVKA ALERLALDPR YHDLLSLVKT ARNGAVYGTK VRFPHALVII FLFRSGTFRQ
     KMGLVMRATR KHATNLARFA TIYKLVVLAL RHWGPTPGKE GPYDTFIAGL VGGYIVFGQR
     SKRNGKVSSV SQQIVIYIFA RVALALARIA VKPGHGFPVV SKEPLHSQIS HYAWPAFASL
     SWAMVMFLFK THPEDLQSSL RSSMTPVDDL NAAVDSFFGQ ALGVVATRSV LGAFLAALEA
     LENPDIWIQV GTRTLSVLSS QPSSFFDAQA TLCDLVATAH EANEDFADAA RVLTEIPLDS
     SQRKVTDEER ACIWVRIVRN YLEDEDPTAA ETYVNKLKNI MHTVSDPDLN LHFRLSQARI
     QDAKRDFLSA SQRYHDISLS PAVAEEERLH TLAMAVKCAV LAPAGPMRSR TLGRLYRDER
     SVQLDEFGIL EKMFLDRLLS QAEVDKFAEA LGPHQLATTS DGSTVLARAV VEHNLLGASR
     LFNNIRFEAL GALLGLDAAK AEETTARMIE QGRLVGRIDQ LDGIVWFQGG EASGEKGSGR
     AEVVAGKEMR TWDANVESLS EDVENVTNSL QREFPDFVAA NLAV
//