ID   A0A0B2WWS6_METAS        Unreviewed;      1344 AA.
AC   A0A0B2WWS6;
DT   04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT   04-MAR-2015, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Thermotolerance protein {ECO:0000313|EMBL:KHN97877.1};
GN   ORFNames=MAM_04266 {ECO:0000313|EMBL:KHN97877.1};
OS   Metarhizium album (strain ARSEF 1941).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Clavicipitaceae; Metarhizium.
OX   NCBI_TaxID=1081103 {ECO:0000313|EMBL:KHN97877.1, ECO:0000313|Proteomes:UP000030816};
RN   [1] {ECO:0000313|EMBL:KHN97877.1, ECO:0000313|Proteomes:UP000030816}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ARSEF 1941 {ECO:0000313|EMBL:KHN97877.1,
RC   ECO:0000313|Proteomes:UP000030816};
RX   PubMed=25368161; DOI=10.1073/pnas.1412662111;
RA   Hu X., Xiao G., Zheng P., Shang Y., Su Y., Zhang X., Liu X., Zhan S.,
RA   St Leger R.J., Wang C.;
RT   "Trajectory and genomic determinants of fungal-pathogen speciation and host
RT   adaptation.";
RL   Proc. Natl. Acad. Sci. U.S.A. 111:16796-16801(2014).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KHN97877.1}.
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DR   EMBL; AZHE01000009; KHN97877.1; -; Genomic_DNA.
DR   STRING; 1081103.A0A0B2WWS6; -.
DR   HOGENOM; CLU_003539_0_0_1; -.
DR   OrthoDB; 2087067at2759; -.
DR   Proteomes; UP000030816; Unassembled WGS sequence.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 3.
DR   InterPro; IPR018846; Cleavage/polyA-sp_fac_asu_N.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   PANTHER; PTHR10644:SF21; CLEAVAGE_POLYADENYLATION SPECIFICITY FACTOR A SUBUNIT N-TERMINAL DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR10644; DNA REPAIR/RNA PROCESSING CPSF FAMILY; 1.
DR   Pfam; PF10433; MMS1_N; 1.
DR   SUPFAM; SSF50993; Peptidase/esterase 'gauge' domain; 1.
DR   SUPFAM; SSF101908; Putative isomerase YbhE; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000030816}.
FT   DOMAIN          156..692
FT                   /note="Cleavage/polyadenylation specificity factor A
FT                   subunit N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF10433"
FT   REGION          480..519
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        480..496
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1344 AA;  149167 MW;  2DF2AFC6DB65F2EA CRC64;
     MAFQTSIRRD GEWVTETVNF QAALKAYATP KSASRPHPEP PSCGILSRTI VDSPMIHQIL
     PVRLRSEAHN DIAFVGLWQD HFVQISELRR DGQVHEVVRK SDFGSRIRRA AVLGDSPQHG
     LDDDDLADMV KSEDKEMLVR GSFATEPHSR HRLPPQLLVL VLESGDTMYM FLRERQDSTL
     EFVIHKRESP RNLSYFGYHL SVDPSSRYMA AASPDGVLVI YELESMVALS EKYRLQGFVD
     PIKSIRIRVI QGVVHKLEFL YPRPEDDYHI ILLLIVTRKE RRSAEPVSRM LTYEWEVGDN
     LKEVFAEEKT GNRLPKEHRM PSLLIPLRFN TAFFTVSQPD IGIVKNCLSG SPVFEVLDTD
     TPERTPLHHG IGNPLWTAWS RPFRRKKYFE KTDIIYLARE DGAIIHVEID APELVPSVTT
     VGCLNTNINT AFTIAYDIFS DVLIIGGDSG PGGIWKLAPR TDLEQVSVLP NWSPVVDMAT
     SSGRPLKASS TSEHRNANSR SPERKNLPSR PDSLFSASGR GIRGNLTQWR WGIQGRIGLD
     IETGEPIRRS WGLTMNGPEG NGLYGLLALP NSSTLLHFSA DFNQVDAVGA DSTAFDLTSR
     TLHAYQAQSG LIVQITESSI ALILDSQASL HALPSILGIT GIRAENAFGA DDLLVLSTHN
     DGNFQLHILQ VEGMNIRAVN SWGIAGEATC VSLFKIAGNY CVISGSVIDS TSWVSAYALD
     GTAVIAEAVD RRTADASARE IPNEAYLFEP LTSICIVRET TDSADFVAGT RCGHVLNFRI
     LDQTSKRVTW NSEAMGVAPV DVFPTRGEFG GDVAAMACCD NNLTMMSNFS PSALKFQNKN
     FIWLTDSNDA SMPSPAVHSV FGLGVSLSGH SGHMSLMILA GSRLLFAEVW PHFSLIPRSL
     PLNGTPTRVI FSQAWNCLVA AILQDGKSTL AFIDPDSGMH IASACDKDRN PLQFIWGLGH
     SDDRIYGLGE WLYVKDGKTF AFLLVTTKEG RLLIVSVNKL ESRPGRGGAG RLQYWTRWKK
     MLAKPIYSIV GDNDGIIYCV DRTIHWDVLD LTEKKLRPVK EYEVDSPVTS LRVFNGKIFA
     LTTMHSLEVI DHRAGEDNTM SLIHTDAISR ITIHMTDIGT DGGASDVVGR WPITLLSDHR
     GGLAGVWIPW GQRDKEFQTI FEATLPTSIR RFTHARSRPL WVGSETRNRY GVVASSEEGS
     EVFGVSLDGS LRHFTLVNLE LWRILSLMQT LALRRRLFNV MGGSPSDSDS MVSDDDNDIE
     PHVHPKLMHI DGDLLSRCLE NRLLEKIIGT ADGLDLFCEY LDALDGGRWT DRFRDGIGSS
     EGEREAAYFN LGYDILGYIL APVL
//