ID A0A0B2WWU5_METAS Unreviewed; 563 AA.
AC A0A0B2WWU5;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=rRNA adenine N(6)-methyltransferase {ECO:0000256|RuleBase:RU362106};
DE EC=2.1.1.- {ECO:0000256|RuleBase:RU362106};
GN ORFNames=MAM_04927 {ECO:0000313|EMBL:KHN97330.1};
OS Metarhizium album (strain ARSEF 1941).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Clavicipitaceae; Metarhizium.
OX NCBI_TaxID=1081103 {ECO:0000313|EMBL:KHN97330.1, ECO:0000313|Proteomes:UP000030816};
RN [1] {ECO:0000313|EMBL:KHN97330.1, ECO:0000313|Proteomes:UP000030816}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ARSEF 1941 {ECO:0000313|EMBL:KHN97330.1,
RC ECO:0000313|Proteomes:UP000030816};
RX PubMed=25368161; DOI=10.1073/pnas.1412662111;
RA Hu X., Xiao G., Zheng P., Shang Y., Su Y., Zhang X., Liu X., Zhan S.,
RA St Leger R.J., Wang C.;
RT "Trajectory and genomic determinants of fungal-pathogen speciation and host
RT adaptation.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:16796-16801(2014).
CC -!- FUNCTION: Mitochondrial transcription factor that confers selective
CC promoter recognition on the core subunit of the yeast mitochondrial RNA
CC polymerase. Interacts with DNA in a non-specific manner.
CC {ECO:0000256|ARBA:ARBA00024915}.
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. rRNA adenine N(6)-methyltransferase family.
CC {ECO:0000256|RuleBase:RU362106}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KHN97330.1}.
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DR EMBL; AZHE01000011; KHN97330.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0B2WWU5; -.
DR HOGENOM; CLU_014537_1_0_1; -.
DR OrthoDB; 2716134at2759; -.
DR Proteomes; UP000030816; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR Gene3D; 1.10.8.100; Ribosomal RNA adenine dimethylase-like, domain 2; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR001737; KsgA/Erm.
DR InterPro; IPR023165; rRNA_Ade_diMease-like_C.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR11727; DIMETHYLADENOSINE TRANSFERASE; 1.
DR PANTHER; PTHR11727:SF17; DIMETHYLADENOSINE TRANSFERASE 1, MITOCHONDRIAL; 1.
DR Pfam; PF00398; RrnaAD; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000256|RuleBase:RU362106};
KW Reference proteome {ECO:0000313|Proteomes:UP000030816};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW rRNA processing {ECO:0000256|RuleBase:RU362106};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW ECO:0000256|RuleBase:RU362106};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU362106}.
SQ SEQUENCE 563 AA; 63923 MW; 460360CC880AF5B8 CRC64;
MLSVTSDIAR QLDLTGVWKR AGGRKKVNAM RAIEPRRVNI VSEALCDDII RYIAPSLERH
RGCDLVDLNP GVGVWSRKLH GFLEPRKHVM MDLDAELYSG FLTDLVSKDN VKLIAKSGLV
WKDMLEMLHT SLSDQQQQVA QKDTPRRNDT LLVTANLSTF PKKAFHGFDS ISSMILYQFI
SSIRTSTLFH RYGLIRMLIW VNDEDKRRLL PRSIHRRKRS AFEAEISCEW VHEVAGLDAK
VQDRNALRDE WINTESAAQT LERMRAAGLS MPKGRETLMY SKLQGEPELL GQKLAGERPP
SLTRPFKQEL EELAQQGFSE SAETSKRLKA LRQREKYDQQ AALMYLGLLQ ERDAVAALSA
SSPTEFERAN AAWNEKIDCL KKNARNEFNG IRDSYHVFRQ SPPAMLWDRR PYEPLSARGE
EFFPNAPTAL LDIQPKAMHP VFRQHGPNSS RSGDMSDVML RFWLHHTLLP IQKAMEGLWG
GFGHLITECP SVRDPSRGGT PMTGNGALTV RAMNGEQWAE IMEAWMNWPF MPSYTQMLGR
LVEEVDGDGD EEDTKSGATG LEI
//
