ID A0A0B2X4Q3_METAS Unreviewed; 10302 AA.
AC A0A0B2X4Q3;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Nonribosomal peptide synthase {ECO:0000313|EMBL:KHO01329.1};
GN ORFNames=MAM_00330 {ECO:0000313|EMBL:KHO01329.1};
OS Metarhizium album (strain ARSEF 1941).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Clavicipitaceae; Metarhizium.
OX NCBI_TaxID=1081103 {ECO:0000313|EMBL:KHO01329.1, ECO:0000313|Proteomes:UP000030816};
RN [1] {ECO:0000313|EMBL:KHO01329.1, ECO:0000313|Proteomes:UP000030816}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ARSEF 1941 {ECO:0000313|EMBL:KHO01329.1,
RC ECO:0000313|Proteomes:UP000030816};
RX PubMed=25368161; DOI=10.1073/pnas.1412662111;
RA Hu X., Xiao G., Zheng P., Shang Y., Su Y., Zhang X., Liu X., Zhan S.,
RA St Leger R.J., Wang C.;
RT "Trajectory and genomic determinants of fungal-pathogen speciation and host
RT adaptation.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:16796-16801(2014).
CC -!- SIMILARITY: Belongs to the NRP synthetase family.
CC {ECO:0000256|ARBA:ARBA00029454}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KHO01329.1}.
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DR EMBL; AZHE01000001; KHO01329.1; -; Genomic_DNA.
DR STRING; 1081103.A0A0B2X4Q3; -.
DR HOGENOM; CLU_222660_0_0_1; -.
DR OrthoDB; 2787863at2759; -.
DR Proteomes; UP000030816; Unassembled WGS sequence.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0044249; P:cellular biosynthetic process; IEA:UniProt.
DR CDD; cd05918; A_NRPS_SidN3_like; 8.
DR CDD; cd19542; CT_NRPS-like; 4.
DR CDD; cd19534; E_NRPS; 3.
DR CDD; cd19545; FUM14_C_NRPS-like; 4.
DR Gene3D; 3.30.300.30; -; 8.
DR Gene3D; 3.40.50.980; -; 2.
DR Gene3D; 1.10.1200.10; ACP-like; 9.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 11.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 7.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 11.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 7.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR PANTHER; PTHR45527:SF3; SIDEROPHORE SYNTHETASE (EUROFUNG)-RELATED; 1.
DR Pfam; PF00501; AMP-binding; 8.
DR Pfam; PF00668; Condensation; 11.
DR Pfam; PF00550; PP-binding; 8.
DR SMART; SM00823; PKS_PP; 5.
DR SMART; SM01294; PKS_PP_betabranch; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 8.
DR SUPFAM; SSF47336; ACP-like; 9.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 22.
DR PROSITE; PS00455; AMP_BINDING; 7.
DR PROSITE; PS50075; CARRIER; 8.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 5.
PE 3: Inferred from homology;
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000030816}.
FT DOMAIN 587..663
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 1698..1774
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 2800..2876
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 4356..4432
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 5492..5568
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 7046..7122
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 8581..8657
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 9666..9742
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT REGION 5378..5404
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 10196..10220
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 10302 AA; 1135884 MW; B1B545CA3C432419 CRC64;
MSAAAQTDVQ NFSSLHDNVP QHAENTTATL QDLQVIWKWN ESFPEVVDGR VHDLITHRVQ
LQPEEQAVCA WDGNWTYRQL DELSTNLAHR LVHMGVGPHV IVPLCFLKSK WTPIAKLAVM
KAGGASVALE TTLPYDRLYS IVRQVKPILI LSSPWTTELA GRLTTQPVLV VDETSTTPDI
ASTLPEVQPW DKLYLVFTSG STGTPKGTII THSNFCSTIH HQRAVLGYSS SSRVYDFAKY
SFDVTWSNFI YTITAGGCLC IPSQQEALSN LVGSIRAYNA NYLNITPSVG SMIRPSDLNG
ILKHVIFAGE ALTSHLASQW AQHTRVINLY GPAECTVGAT LVVLNDDVNK KSLGTSIGRG
VGFCTWIVDP SCHDKLVPIG AIGELILEGP CVGAGYIGNA EKTAEAFIQA PKWLVAGPAV
PLERQRPAQL YKTGDLVRYE ADGQLTFIGR KDSQVKINGQ RVELGDIEHH VRTYAVDGAD
VQVAAELVTP FGSDKPLLVA FMQISTQAAS QGEDGLEAEL KRVIHGLNDR LAAAVPAYMI
PTAYIPLAAF PKNANGKTDR RKLKEMCEAY SVEDFMARGS PVSEKKKPTR HIEFRLQELW
SHVLGLNVVS IGTDDSFLRL GGDSIAAMKL AGAARERGLS LSVADIFNHP VLCEMADVVS
EHSETSNYIY PFSLLKDHID VTLARSQVAD ACGVNIADIE DVFPCTPLQE GLMALTAKHP
GDYVSRHIFQ LQPTVDIDRL KKAWEQVVAM TPILRTRIVD LSQQGLVQVV LDQPTDCTLK
DGETNLEKYQ KEDAKLTTGL GKPLVRFALF QELYGEEIRR FFVWTIHHSL YDGWSKPLLL
ERLAEAYTGE RALLPSPQFQ CFVKHILDMQ QGQATKFWSA QFENSEAQTF PVLPSPRYQP
RSDKLVTHAI EKLQWPKMMG VTASTMLRAA WSIVTSCHTN ASDTVFGVTV SGRQASLPGV
DQMTGPTIAT VPVRIVLDKK KTIEELLLQI QRQVVDMTAF EQTGLQRIRL VSPEAERACD
FQTLLVIQPA ADEKEKAIHD SLFSPNSDHE HWSLDDDMAE FRTYPLSLEC HLRDQGVVCL
TRFDSAVLSG KQIAILMRQL EHVVRQLCSA ESAQKKLEDV ALVSREDLQQ MWHWNSTVPD
TADGVVHDLI AETTRQQPEA QAVCAWDGDW TYRELDDVST RLAHRLVALG VGPEVVVPLC
IEKSRWMPVA MMAVMKAGGA SVAIDYAQPE DRLSSIVKQV SPVVMLTSIA NQDLARRLVP
HLSVVVVSEQ HLASLPQAHG ARTPKTPTTA GTALPTVSQS NTLYVVFTSG STGAPKGVVV
THANLTSAIR HQRETLGFTK QSRIYDFASY MFDVVWCNLL QGLSAGGCLC IPSNEDRRND
PLGAITRLGA NTAIFTPSTI RGLDLRPLEG LRHIHFIGEA LSADDVGGLH PECAVTNLYG
PTECTTFSTA QQVTVHKASS SGKHQQIGIG AGLGLRTWLV EPFDHSKLVP LGCVGELLLE
GPLVAAGYLG EDEKTAAAFI TDPAWLLDGC ANRGSRHGRL YKTGDLARYD TDGNLVFLGR
KDSQVKINGQ RVELGDVEHH VQSSILHNQD INVVAEVVKP KDSSNAILVV FIQIDIVTVP
GDDEAMHSEL GKITAALPDR LVARVPAYMI PSAYIPVRNI PVTPTGKIDR RKLRAMGQQL
TLEGIMRTNM PRSSGRSQPF TSTEKRLQRL WAAVLGLNAE IIAADDSFFR LGGDSITAMR
LVAAAREQSI TLSVADVFQH PLLSDLAAVV VEEAVGASCK DSHQLEPFAL LNLGEGLESL
KEKIADKCNV GASQVADAFP CTPLQEGLLA LTAKRPGDYV ARFIYPLLPS VSTDQFIKAW
EAVVSATPIL RTRIVDLSER GLVQAIINEP TTWSRKDESI SLEDYDIADR KLTTGLGTPL
VRFAVLQDPV NSSRFFVWTI HHALYDGWSI SLMLKNLEAA YGLTEGSALS SSPPLQTFVK
HIMDIDQSLV ASYWDEQFQS SEAQIFPSLP SATYQPMSNS FITHRMQDIL WPKSDVTPSL
LIRAAWSVLA AKYTDSSDIV FGVTVSGRQA TVLDVEKMIG PTIATVPVRV AFDWTKMTVE
HLLRQVQTQA VEMTTFEQTG LQRIRRVSTE AERACGFQTL LVVHPVEDEE DKNTASRWFI
SRRDEHGEDD TNVTEHDTHA LTMECSLERQ GLRLRIAYDA NIMDAEQVQR LASQFEHIIR
QICMPENASK DLSSINAVSD QDMRDIWKWN DTCPEVLDTC LHEIISKTAK TLPDVPAVHA
WDGGFSYREL DDISTDLALY LAGVGVGPEK IIPLYFEKSK WTPIAMLAVM KAGGASVLMD
SRQPKDRLQA IIDQIKPVVV VSSRSNEKLA NKLTNAPIIV VSSKRLEKTR SEKMLGRLPQ
VQPWNKAYLI FTSGSTGIPK GAILTHANVC SAVRHQQLAQ GYTPDARVYD FTSYAFDTAW
NNFMHTFTIG ACLCIPSENE RRDDLAGSID RFKPTILDIT PSAATALQSS TIQSLRTLIL
GGERLSREYA ERWGAIVDLK LCYGPCECTP TATVATISPN LMGEPTIGRG IGMLSWIVDS
KDHNALVPVG ATGELVLEGP LVGHGYLGDE AKTNEVFIRD PLWLLRGGAG HSGRQGRLYK
TGDLVKYNSD GTLLYVGRKD AQVKINGQRV ELGEVENHMA SHPLTRHAAA LYPQSGPCAK
KLVGVFSLEG IYQADNSPHI ELIGREDSTV VQEHICALET LLGEALPSYM VPCLWIAIKD
IPLNPSGKLN RRAVNDWLVR MNSDMFARIN YSAVTTATHE PRTDAERILC EACSTILNIP
FSEVNLQRSF VANGGDSISA MRLSSHCRAA SLVFSVGILL RSKSLADVAR LSTIASDSKV
NPAKECREDF GRAFALSPIQ KWFFAQTPSE TLTDKDYYCN QGFYVRVIRP VLTEVVSLAV
STIVKRHSML RAKFEQSKSG WMQSVPKPSD GIYHFGSGEA QSIHEIKAHT HKRHQTLDIT
RGLVFAADVY NLPSGDQYLT FIAHHLVVDL VSWRIILDDL EALLTGKTLL DGLPFQLWSE
LQSTEAQAPR FMPEKVLSTK NVHNDHRFWN FTEHISNTAT DHIEKKIEID RATTSLLLKD
ANTAYGTEPV DLILSSIWNA FFHVFHQREG LTIFNEGHGR EPWTADIDLS RTVGWFTTIS
PIHVSRGEGN SLANITRLVK DARRRLPSNG LAYWVSRHLH SQGIAAFESH ASTMEVQFNY
HGQFQQLERS DSLFEVVNFD DSVSPVGPSL PTSVLFDINV VIEAGITKFS FSWNRHLAHQ
KMIEAWIGQI NPSLQSICFE LSKKGPERTL CDYEFLKLDY RGLDELHRNI LHHIEALNET
QVDMVYPSSP MVDGILLSQM KGTGSYETSQ TWEIRSRGSH KININALVDA WHAVVARHPA
LRTVFIHSMD ASVAFNSVVL KSCRGDVVLV ESQSFESALE RLKELPSINY SLDKPAHRLV
LCTIPGDNRV VCKIEMSHAI SDGASTVITM QDWAKAYSGE LDVSELVDIS HGLALALTSV
SKVDKMAYWK KKLSAMEPCH FPRLAEASSA ANEHVTGVTT LEIGPETFHR IQQFCEARSV
TPASLFQGAW ALTLSAYTGS DSVCFGYLAS GRDLSVGGIM ESIGAFANVM ICRAETSREW
SGEDLINYIH DQVLEDLGFQ HCSIADIQHE LGLPFGQNLF NSIISFQRDN DNLGEGMETE
DLVFVDLEWE DPTEYDITIS IRHTNTSVCF TVDHRLSCLS NDQARSVVSL LEKMVTFLVS
DDKVGSSAVN KLPNQLFAMD TISEKDLQDI WRWNEAAPEA IHGLIHDAIT DVARKRPHAP
AICAWDGDLT YTELDGIATK LSHHLANLGV GPDVIVPLYF EKSKWMPVAM LAVMKAGGAS
VALDSTLPEE RLRSIIQQVR PVVTLTSLAN QERAKRLTDC VTVPVSAAHL AKLSIASGSL
PDVKPDNKLY IVFTSGSTGV PKGVMITHSN FCSAIHYQQE ALGFRSTSRV YDFVKYAFDV
TWSNFLHTMT SGACLCIPSE NETSNDITGS FISYRANFAD LTPSVASTLR PADLTTLDHL
LFSGETLTTH LATQWAERAT VLNTYGPAEC SVKATFAAVG KADTTAASIG PGFGMCTWIV
QPNNHNKLVP IGVVGELLLE GPLVGAGYLN DVAKTQESFI EDPAWLVHGA PGQVGRRGRL
YKTGDMVRYN IDGSMTFVGR KDAQVKVNGQ RLELGDVEHH VRNNLIYNGP VQVFAEVIKP
KNGEKSVLLA FIHVDDGAAM TARRQSEQTS EITAGLNERL AARIPGYMIP SAYLLLDEAP
VTATGKTDRR RLREIGQRLT FEEVMALNSR SGEYKHPSTA MERRLQTLWA SVLGISADSI
SADDSFLRIG GDSIGAMKLV GIARDEGLAL TVTDIFKQPK LSDLAKVVGK LSDAVSETIQ
PFSLLKPTID AKAALDQVAN LCQVDGSKIE DVFPCTPLQE GLLALTAKRA GDYVAQYVLP
LKAATDITRL KRAWEEVLQK TPILRTRIVD LPGQGLVQAV LKEFDSWSQC SSVSEYQQAD
ERVVMGMGKP LVRYAVTNVP DHKQRFVFIW TVHHALYDGW SMPRIMDRLE LAYKGEVALR
EAPPFQRFVK HIINVDEERT KRFWQTQFEG SEAQVFPALP SPTYQPTANS SVTYYIDGLH
WPKTDITAST TIRTAWSILV ARYTNSADVV FGVTVNGRQA AVHEVDEMTG PTLATVPVRV
AFNWEQSVES CLNQVQEQLV EMADFEQTGL QRIRQMGVNA RQACDFQTLL LIHPPEESQQ
LETQIFARKG PQDEDEEQDQ LAQFDTHAIT IECDLAHHGM TLRIEFDNNI MNPHQIEKLA
GQLEHVLRLL CDPEQRKMRL TNIETVSKED LEDIWGWNAS VPETVETPVH EMVIAMSQKQ
PDAPAICAWD GDWNYRQLDD LSTRLAHHLQ RLGIGPEVIV PLCFEKSKQT PIAILGVMKA
GGVCVTIDPN LPEDRLVSIV QQVQPMLILS SLANEALATK LSAGNPVVVI DDKLLSSLEM
PAFESLPKVQ PSNTLYVVFT SGSTGTPKGV RITHSNFSSA MLHQHSCHNF DSIPNPRVYD
FASYAFDTSW QNMLATFDCG GCLCIPSEAE RRDDLAGSIE RFRITHSELT PSAAMVLPLS
TLKSLDTLVL GGERLQEEYA KRWASLVNVK NSYGPCECTP TSTVADVDPV NFNGASIGRG
RGVNTWVVDT TTGDSLVPVG SVGELMLEGP LVGPGYLGDP EKTASVFINN PPWLTRGAPG
HPGREGRLYK TGDLVCYNED GTLTFVGRKD AQVKIHGQRV ELGDIENHIM RHHLTRQSAC
LLPKTGLWAN TLVSVFSLQK LQQTLDEVVA ASGQLSPSLA SVSSSASPDT DLTSSTWDSI
EDSTTPASQL STEIVLEDST ASIQDYIAAM QSILESSLPS YMVPTKWIAL KEIPLNPSGK
LNRKQVEHWL ADMDRETYGK LSSIDNNLAC REPETEAERV LRDACSLILN IPAPEINLQR
SFVANGGDSI SAMRLSPHCR AANVVFSVAT LLKARSLSEV AKLSSAATNF ILPRTEDFGK
LCPLSPIQQW FFNQSPEHLV NTAGYYCNQS FYVRINQVVN TRQVRTAIAK VVELHSMLRA
RFQKRDNVWM QIIPRATDAV YHFDAVKLKS MGEMQSLAAQ RQQSLDFEQG LVFSADLCEL
SEGEQYLILV AHHLVIDLVS WRIILDDLEA LLTGTTLVES LPFQIWNDLQ REEAKSSRFD
PDRVLSTEGI NNDLTFWNFT SETPNATHDH IDKTFIIDQH TTSLALKEAN NAFNTEPVDL
LLSAVWDAFF HTFPLRHGLT VFNEGHGREP WNAEIDISRT VGWFTTMSPI HVSRSIGNNR
VNIVRLVKDA RRKLPANGWA YFASRYLNSK GIEAFGPHDS IMEMVFNYHG QFQQLERDHS
FFDSIALDNV SDVGPNLPAS SLFNINMSIE GGQTHVSFAW NRHISNQSLI RTWIDQIGPS
LNSICESLIS RSSEPTLIDY EFLSLDYTAL DRLQSRIIPE IEALNSTEVE DIYPCSPMVE
GILLSQLKGA GFYETSQFYE IRPRGSRVIN VQRLSTAWEE VIARHPSLRS IFIESLDPRM
AFNQVVLREH RGDVVLLKSE SLDSARALLQ NLTKVNYQQL KPPHRVSLCQ VLETNSILCQ
IEMSHTITDG ASTGIVVEDW TKAYNGVLGK DSLNETSRGF ARALNSSIPE IKKTYWEKKL
AGLQPCLFPH LDKISEPSEV VSWSMVDING AAFATMQKFC ESHSITPASL FHAAWSLTLA
SYTGTHSVCF GYVASGRDLA VPGIGEAIGA YANMMVCRAD ISPEWDKKRF VEYLHHQVLE
DMGHQHCSLA DIQHELGIAS GQQLFNTIMS FQKDIDDLEI GLAGQELDFI DEDGDDPTEY
DVAISVTVGA KGAKLFINCL PSRYSNDQAH RILSLFQTNV ASLVDDNAPH GYESTLRSID
MVSKKDLREI WRWNSSVPET ADTCLHHLIG TTVQRRPEAY AVNSWDGDWT YAELEQTATQ
LCYHLASLGV RPGVIVGLYL EKSRWTSVSM LAIMKLGGAS ILMDSSQPES LLRIIMERAK
PRVLLSSSST REFAAKLTSQ PILVVNDDLL HMLATTTAVP LPVVRPSSVV CILFSAGSSD
SPKASVLTHA NFSSAVKHQQ DALGYKPSSR VYDFMPHSSA ISWQIFSHVF SSGGCLCVPS
QREHKDSLAN SVSRWQPTIM NITPSAATAL PNSTVESLET LILCGERLSP DMARRWAPLV
SLKLAYGCCE GRPIATVGTV CLEDADEPRI GRGVGVNTWV TDTRDGTTLV PIGSVGELVL
EGPLVGAGYL GDAEATEAAL INNPQWLTCG SGEPEHPGRT GKLFKTGDLV RYNKDGSLTF
IARKEAQVKI HGQHVELEDI ESHMVRLPSI RQAACLIPKS GHYADKIVGV FSINGIDDGN
SDTGNTALHL IGRDRAQEVQ DNISSLQAAL DNSVPVYMVP SVWVALKSIP VDYSGKLDRK
LIGEWLCNLD AETYTRISNA GSSSSSPVTT TEKVIQDACS HILNIPSNCV NMQRSFIANG
GDSISAMRVS PYCRAAGILV SVASLLRSKR LVDVAESATV AKGSVSSREE EFDKSFSLSP
IQQWFFAQSP PNKVNTTSYY CNQAFYVQIK RRVLPDEVAI AIGKVVQQHS MLRARFQLDK
LTNSWAQLVP KPSDALYHFA SWQVDSLPAV KSIISQRHQE LDIECGLVFS ADMFTLPSNE
QYLALIAHHL VVDLVSWRII LDDLESLLNG GTALEELPFQ VWHHLQKQEA RSINFAPERV
LSSEVHNELE FWNYTAATPN TFDDHVEESF EVDFATTEIL LRGANRAFNT EPVDLILASV
WNAFFDVFKT RNGLTIFNEG HGREPWAADI DLSRTVGWFT TMTPMHVSRG RTTTDSARVV
KDMRRQLPSN GWAYFTSRYL NDEGIKAFKA HDCVMEVLFN YHGQFQQLES DDSLFENVAF
DDVFDVGSDL PASALFSINV SIEGGLTKFT FSWNRHISHQ NLIRDWIAQV APSMQSLCSA
LSACESSLTI ADYEFLNLDY KGLDELQNRI IPALQSETST IVTDIYPCSP MVDGMLLSQI
RDPEAYKTLL TYEMKHHKNL QPLDIGVLAK AWQAVVARHP ALRSVFIEGV DKRTAFAQAV
LEAYQGEVIV CEAHNKTTAV TMVRQLPSVD YQQLKPAHRL VLCKVLDDDT IICQIEMSHT
IVDGASTAIM LNDWSKAYSG ILGTETLCET NRSFVRALKS SPWADKMAYW KKKLAGLEPC
HFPRLSEACS PGNSIATFGA DIDGDDFIRI QRFCETQSVT PASVFQSAWA LLLSTYASNN
SVSFGYIASG RDLPIDGIGE SINAYANMMI CRADVSRHLT PQGFVKRLHD QVLEDLTFQH
CSLADIQHDL QLSPGQPLFN TIVSFQKDDA DAADNVAVGD LVFIDMDHED PTEFDISFDI
SYGTTQVAFS LDYRLSCLTS EQAKRVMSLL RTIIMSIVDG KTEPTTLNAI DMVSQGDLEQ
IWDWNSVVPE KVEALVHDLI SNTAHKFPNA PAICAWDGDW TYQQLDTLST QLAYKLVKLG
VGPEKIVPLC FEKSRWVPIA MLGVMKAGGT CVALDTALPE ERLRIIMQQV KPTILLSSST
SQVLVNRLTT GLVFVVDEAN VADLETPPAT ATRLSSVTPS NTLYVVFTSG STGTPKGVTI
NHSNFASSLR HQHGAHNFKA GARVYDFASY TFDTSWQNVL SALECGACLC IPSNSERQDD
LAGSLERFGV THAEMTPSAA QLLPASAIKR LDTLILGGEV LSPELAKSWA SMVNVKNSYG
PCECTPTTTV ATIDPDRVDV SSIGRGFGVN TWVVSTAGDS LAPVGSIGEL FLEGPLVGPG
YLDDEERTAA SFIQNPSWLL RGSAARPGRQ GRLYRTGDLV RYQPDGSLTF IGRKDSQVKI
NGQRLELGDI EHYVSCNINY DCDIRVVVDV VKPRDSERRA LVAFLGVEDT SAGLDKIIAG
LADRLAAQVP AYMIPSAYML LASIPMTPSG KTDRRELRAM AEKLTRVELM AHGPSQATRR
APATPKEIQL QGLWAAVLGI PREMISAEDS FLRIGGDSIG AMRLTGLARD GGLSMTVTDI
FRHPCLSDLA KTIRNSFGQE HEAVLPFSLL SGKLDALETR TRIARLCDVG PSLIEDAFPC
TPLQEGLLAL TLRRSGDYVA QNVLQLKATV DIPRLKRAWE QVIATTPILR TRIVDLDTQG
LVQVVVAEEP ATWLECSTGI LCEERDKKLA MGLGKPLMRY AITKDSHDQH CFVWTVHHAL
YDGWSMPLVL ERLEMAYNGA VLQTPPAFQE FVRFIGDVDD DGATGFWTSQ FDQIQAQAFP
SLPSPVYQPR SDAGVSHHIQ DLAWPKTDTT ASTAIRAALS ILIAVHSDAS ESLFGATVTG
RQAPVPGVEN MTGPTIATVP IRVTLDGENT VHQFLQQIQA QVVDMTAFEQ TGLQRIRRIN
ASAKQACDFQ TLLLIHPVEE PGKSTSFLFR DEDEEDVCAD DVVDDSFAGF DTHAITIECD
LENTGVLLRF RFDSQVIDKL QVERLAAQFD LILRQLCDPG MSQRKISDID TVSAGELRKI
WEWNAVVPDA VHHAVHELIA ENASKHPDSP AVCAWDGNWT YQQLDSIATQ VACRLIGLGV
GPDVIVPICF EKSRWTPVAM LAVMKAGGAS VALDATLPRE RLRSIVQQVK PSLVLSSPLS
RELAEALTDG AVMVLGEGCQ EEFDEPPLQP LPRIEPWNKL YLVFTSGSTG VPKGAVITHS
NFSSAIHHQQ AVTGFSRSSR VYDLAKYAFD ISWSNFIHTM AAGGCLCIPS QQAAFDDITG
SILEYNANFI DITPSVASTL RPSDLTCLKT VVFAGEALTN HQASKWSKHA RVLNMYGPAE
CTVKATLAEL DGTAPSSAAS IGRGLGLCTW VVDPSNHLKL APVGMVGELV LEGPIVGPGY
LGDAAKTADA FIESPPWLLR GGPGHQGRKG RVYRTGDLVQ YNPDGSLTFV GRKDGQVKIN
GQRLEVGDVE HNLASTLNAQ CQSEFQLAAE VIKPRDSDKA MLAAFIQSSG QPGDLKSRMN
VLTSGLNDCL AARVPGYMIP SAYIVVDQLP LSATGKLDRK QLREMGAKLT LSELMTSTGP
RAERRPPTSP TELCLQRLWA DILSIDPETI SADDSFLHVG GDSIQAMKLA QRARDEGFHL
AVADILTSPK LSRMASHLKS LNADSGAHPG EYRRFSLLPP GSRPQVEQIL TEHGIATDDV
QDIFPVTDQQ ARYLLTTYTA ARSAVYYHTL DRDGDFDPER LQRACATLVG RLEMMRTVFF
AYKDTFLQAV LARVDADIGM FATATENLDE YTLRLKKQDL LCHLQFGAPL AKISVIHQTR
EQKYRIVIRL SHAQYDGTAL AKMWAAFEAA YASAPPDGKQ TSFSHYMHTL SLLDEQRATE
YWRNMLQGST CTAIKHETTH RLGYALGPNV VKTIAACDLQ SDDFTFATVL KAAWSYVLAR
HSATGDVVFG SLTHGRNQPG TQDIFGPCVN IVPCRVVFQE DWCARDLVAA VNAQQVASIP
FETMGCRDII RNCTSWPRWA FFSSVIVHQN YEDRPADESL VDFDGADLST GDIDSVQVYI
TSTPGADSTQ IDFSFTDKVV TDELAQRLAS ELADTIVQFY SAMDTRIMPP RDIRRLPASL
PLPADPDPEP AAAPPSDERT AALDGCPAEL RAALGAAWRD ALGLQTVPGD ASTETLFELG
GDASNAAQLA AHMQRRGYQL RIEDVFENPS WCELLLHMAG RR
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