ID A0A0B2X5E1_METAS Unreviewed; 1836 AA.
AC A0A0B2X5E1;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=BMR1-like protein {ECO:0000313|EMBL:KHO01599.1};
GN ORFNames=MAM_00600 {ECO:0000313|EMBL:KHO01599.1};
OS Metarhizium album (strain ARSEF 1941).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Clavicipitaceae; Metarhizium.
OX NCBI_TaxID=1081103 {ECO:0000313|EMBL:KHO01599.1, ECO:0000313|Proteomes:UP000030816};
RN [1] {ECO:0000313|EMBL:KHO01599.1, ECO:0000313|Proteomes:UP000030816}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ARSEF 1941 {ECO:0000313|EMBL:KHO01599.1,
RC ECO:0000313|Proteomes:UP000030816};
RX PubMed=25368161; DOI=10.1073/pnas.1412662111;
RA Hu X., Xiao G., Zheng P., Shang Y., Su Y., Zhang X., Liu X., Zhan S.,
RA St Leger R.J., Wang C.;
RT "Trajectory and genomic determinants of fungal-pathogen speciation and host
RT adaptation.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:16796-16801(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCG family.
CC PDR (TC 3.A.1.205) subfamily. {ECO:0000256|ARBA:ARBA00006012}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KHO01599.1}.
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DR EMBL; AZHE01000001; KHO01599.1; -; Genomic_DNA.
DR STRING; 1081103.A0A0B2X5E1; -.
DR HOGENOM; CLU_000604_35_0_1; -.
DR OrthoDB; 5473955at2759; -.
DR Proteomes; UP000030816; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03233; ABCG_PDR_domain1; 1.
DR CDD; cd03232; ABCG_PDR_domain2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR029481; ABC_trans_N.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR034001; ABCG_PDR_1.
DR InterPro; IPR034003; ABCG_PDR_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010929; PDR_CDR_ABC.
DR InterPro; IPR008551; TANGO2.
DR PANTHER; PTHR19241:SF685; ABC MULTIDRUG TRANSPORTER (EUROFUNG); 1.
DR PANTHER; PTHR19241; ATP-BINDING CASSETTE TRANSPORTER; 1.
DR Pfam; PF01061; ABC2_membrane; 2.
DR Pfam; PF00005; ABC_tran; 2.
DR Pfam; PF14510; ABC_trans_N; 1.
DR Pfam; PF06422; PDR_CDR; 1.
DR Pfam; PF05742; TANGO2; 1.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000030816};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 526..544
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 556..578
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 598..623
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 630..651
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 663..683
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 773..794
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1182..1202
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1214..1237
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1258..1284
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1296..1319
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1331..1353
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1448..1468
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 154..411
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 847..1090
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 1..49
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 66..98
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 70..95
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1836 AA; 203973 MW; FB93573F2EA68026 CRC64;
MAPHHLAGQT EAQDDETHGR APASRCQSPD SDLTAGHGRT AGADTGRVLS GVSVEQAEAD
FADLQREFTG ASRASRRGRA VKDGDPEKAG PADLGAADDD ESLFDLETAL RGDLAAGEAA
GIKAKHIGAC WDGLTVKGIG GTANYVQTFP NAFINFFDVI TPLMGLLGLG RKPPEATLLD
GFQGVCNPGE MVLVLGKPGS GCTTFLKAIA NQRHGYTCVQ GHVFYGPWTA KEFSRYRAEA
VYNAEDDIHH PTLTVQQTLA FALDTKMPAK RPGNMTKAEF KEHVISTLLK MFNIQHTRNT
VVGDHFVRGI SGGERKRVSI AEMMITNACI LSWDNSTRGL DASTALDFTR SLRILTNLYK
TTTFVSLYQA SENIFRLFDK VLVIDEGKQV YFGPADEARS YFEGLGFASR PRQTTPDYLT
GCTDEFERVY AAGRSENDSP HSADTLRRAF QKSHHQKKLE SQIAEYKANL EKEQHKHSDF
QLAVKDSKRG ASKRSAYQVG FHLQVWALMK RQFILKLQDR FNLTLSWVRS IIIAIVLGTL
YLNLERTSAS AFSKGGLLFV ALLFNAFQAF SELAGTMFGR AIVNKHKAFA FHRPSALWIG
QIIVDQAFSA TEIMVFSIIV YFLSGLVRDA GAFFTFYLMI LSGNIAMTLV FRIIGCLSPD
FDYAIKFAVV VITLFVTTSG YLIQYQSEKA WLRWLYWVNP LGLVFSSLMQ NEFQSIDMTC
TADSLIPSGP GYTNISHQVC TLPGSKPGTT FVAGPDYIAQ GFSYYAGDLW RNWAIVFSII
VLFLILNVVL GELVKFGMGG SSFKVYQRPN KERAALNEKL LQKREARRKD RSNEVGSDLS
IKSESILTWE NLNYDVPVPG GTRRLLDNVF GYVRPGELTA LMGASGAGKT TLLDVLASRK
NIGVITGDVF VDGFKPDKQF QRSTSYAEQL DLHEPTQTVR EALRFSADLR QPYETPLAER
HLYVEEIIAL LEMEHIADCI IGNEEAGLTV EQRKRVTIGV ELAAKPELLL FLDEPTSGLD
SQSAFNIVRF LKKLAAAGQA ILCTIHQPNA TLFENFDRLL LLQRGGRTIY FGEIGEDASI
LRAYLKRNGA EAAPTDNVAE FMLEATGAGS SPRIGERDWA DVWDESPELA CVKKAIVEMR
EERAAIAQIA NPVPEKEYAS PTHHQIKVVV RRMYRVFWRS PNYLFTRLFN HFAVAFVSGL
TYLNLDTSRS SLQYTVFIIF QVTVLPPLII SQVEVMFYIK RAIFFREASS KMYSPTTFVT
AIIAAEMPYS ILCAVVFFVC LYFMPGLDAT PSRAGYQFLM VLITEVFAVT LGQGLAALTP
SPRISAQFNP FLTIIFALFC GVTVPAPQIP AFWRAWLYHL DPFTRLISGM VTTALHELPV
DCTSSEVNRF IAPSNMTCGE YMAPFFERGA PGYLVRNDTQ DCEYCAHKVG DEFYERLNMS
FDDRWRDLGI YVAFIVSNLI ILFIAYDFQE RFPRETSQHT PSTASSDLHQ DNMCIVLFTT
AHPDYPLILI DNRDEFILRP TSRPHWWTHP TSGELVLSSR DLQRAEKGTW LGITKSGVFA
VLTNYREANA YDASRPVHGR RSRGAVVTAW LAGLGNSIKD GVQRLVEDDG VKGVGGFSLV
CGKLRKRGEG IAVISNRAED ADQVPIVAGQ RGETWGLSNT TFDAEVAWPK VEMGTRMLRA
TVQRAAEDKA SEADLIKDLF KVLDTDTFPA IRAGTSFQEI TGLLRHSIFV PELGDESQRE
SMDAARAKGK ATWARDEGKL KAVEEILLEQ QPELSAPAAN GFETGTYGTQ RQTVVLVDWD
GNVKMVERAL WDRNGHGIGR GDGDVVIEFA IEGWDE
//
