ID A0A0B2X771_METAS Unreviewed; 530 AA.
AC A0A0B2X771;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Cytochrome P450 78A3 {ECO:0000313|EMBL:KHO01320.1};
GN ORFNames=MAM_00321 {ECO:0000313|EMBL:KHO01320.1};
OS Metarhizium album (strain ARSEF 1941).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Clavicipitaceae; Metarhizium.
OX NCBI_TaxID=1081103 {ECO:0000313|EMBL:KHO01320.1, ECO:0000313|Proteomes:UP000030816};
RN [1] {ECO:0000313|EMBL:KHO01320.1, ECO:0000313|Proteomes:UP000030816}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ARSEF 1941 {ECO:0000313|EMBL:KHO01320.1,
RC ECO:0000313|Proteomes:UP000030816};
RX PubMed=25368161; DOI=10.1073/pnas.1412662111;
RA Hu X., Xiao G., Zheng P., Shang Y., Su Y., Zhang X., Liu X., Zhan S.,
RA St Leger R.J., Wang C.;
RT "Trajectory and genomic determinants of fungal-pathogen speciation and host
RT adaptation.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:16796-16801(2014).
CC -!- COFACTOR:
CC Name=heme; Xref=ChEBI:CHEBI:30413;
CC Evidence={ECO:0000256|ARBA:ARBA00001971};
CC -!- SIMILARITY: Belongs to the cytochrome P450 family.
CC {ECO:0000256|ARBA:ARBA00010617}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KHO01320.1}.
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DR EMBL; AZHE01000001; KHO01320.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0B2X771; -.
DR STRING; 1081103.A0A0B2X771; -.
DR HOGENOM; CLU_001570_5_11_1; -.
DR OrthoDB; 2954533at2759; -.
DR Proteomes; UP000030816; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0004497; F:monooxygenase activity; IEA:InterPro.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR CDD; cd11069; CYP_FUM15-like; 1.
DR Gene3D; 1.10.630.10; Cytochrome P450; 2.
DR InterPro; IPR001128; Cyt_P450.
DR InterPro; IPR002401; Cyt_P450_E_grp-I.
DR InterPro; IPR036396; Cyt_P450_sf.
DR PANTHER; PTHR24305; CYTOCHROME P450; 1.
DR PANTHER; PTHR24305:SF227; P450, PUTATIVE (EUROFUNG)-RELATED; 1.
DR Pfam; PF00067; p450; 2.
DR PRINTS; PR00463; EP450I.
DR SUPFAM; SSF48264; Cytochrome P450; 1.
PE 3: Inferred from homology;
KW Heme {ECO:0000256|ARBA:ARBA00022617}; Iron {ECO:0000256|ARBA:ARBA00022617};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022617};
KW Reference proteome {ECO:0000313|Proteomes:UP000030816};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 28..50
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 530 AA; 58978 MW; 981EBD15EF3E54B5 CRC64;
MLMLLQGLVV AGGASCMLQI KAPHSSLGFW TTASGIFLAY FFLAQIWRII VYPRFFSPLR
HLPHPRDGHW LWDQTMRILK EPTGVPMRNW LDSTPNDGLL VYSTWFEQRV LVTNPKGLAE
VLATKNYDFE KPKQFSQSLG RFLGLGILFA ERDEHKRQRK NLMPAFAFRH IKDLYPTFWI
KSQEMAELLS ATIKAKSDPG AAEKNKTQAG PNGLAHPPGA IEVYDWSSRA TLDIIGVAGM
DRDFNSLKNP ANKLNQVYKT IFNPGGVERF TRLLAQFVPI QLVRLLPLKR NAEMSEASSY
IKQVCRDLIA GKREQLSTQK RRSGADVDIL SVALASGGFS DEDLVQKHLR DQVRPKLASL
GDAITAAEID SCSYLQAFCN EVLRVWSPVP LTLRVAAKDT SILGQFIPKG TPVILCPWAV
NLSEKLWGAD AGQFKPERWL DADGHTNNRG SADSNYSFLT FLHGPRSCIG QKFAQAELAC
LVAAWVSRFE TRFEDGGPLA KGEEPGIATG VTSKPKGGLW VQLAEIEEGH
//
