ID A0A0B3BYP8_9PSED Unreviewed; 1211 AA.
AC A0A0B3BYP8;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=Urea carboxylase {ECO:0000313|EMBL:KHO64507.1};
GN ORFNames=PT85_09870 {ECO:0000313|EMBL:KHO64507.1};
OS Pseudomonas flexibilis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=706570 {ECO:0000313|EMBL:KHO64507.1, ECO:0000313|Proteomes:UP000030980};
RN [1] {ECO:0000313|EMBL:KHO64507.1, ECO:0000313|Proteomes:UP000030980}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 14085 {ECO:0000313|EMBL:KHO64507.1,
RC ECO:0000313|Proteomes:UP000030980};
RA Shin S.-K., Yi H.;
RT "Genome sequence of Pseudomonas tuomuerensis JCM 14085.";
RL Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=biotin; Xref=ChEBI:CHEBI:57586;
CC Evidence={ECO:0000256|ARBA:ARBA00001953};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KHO64507.1}.
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DR EMBL; JTAK01000004; KHO64507.1; -; Genomic_DNA.
DR RefSeq; WP_039606561.1; NZ_JTAK01000004.1.
DR AlphaFoldDB; A0A0B3BYP8; -.
DR STRING; 706570.PT85_09870; -.
DR OrthoDB; 9763189at2; -.
DR Proteomes; UP000030980; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd06850; biotinyl_domain; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 3.30.1360.40; -; 1.
DR Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR Gene3D; 2.40.100.10; Cyclophilin-like; 2.
DR InterPro; IPR011761; ATP-grasp.
DR InterPro; IPR005481; BC-like_N.
DR InterPro; IPR001882; Biotin_BS.
DR InterPro; IPR011764; Biotin_carboxylation_dom.
DR InterPro; IPR005482; Biotin_COase_C.
DR InterPro; IPR000089; Biotin_lipoyl.
DR InterPro; IPR005479; CbamoylP_synth_lsu-like_ATP-bd.
DR InterPro; IPR003778; CT_A_B.
DR InterPro; IPR003833; CT_C_D.
DR InterPro; IPR029000; Cyclophilin-like_dom_sf.
DR InterPro; IPR016185; PreATP-grasp_dom_sf.
DR InterPro; IPR011054; Rudment_hybrid_motif.
DR InterPro; IPR011053; Single_hybrid_motif.
DR InterPro; IPR014084; Urea_COase.
DR NCBIfam; TIGR00724; urea_amlyse_rel; 1.
DR NCBIfam; TIGR02712; urea_carbox; 1.
DR PANTHER; PTHR18866; CARBOXYLASE:PYRUVATE/ACETYL-COA/PROPIONYL-COA CARBOXYLASE; 1.
DR PANTHER; PTHR18866:SF33; METHYLCROTONOYL-COA CARBOXYLASE SUBUNIT ALPHA, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF02785; Biotin_carb_C; 1.
DR Pfam; PF00289; Biotin_carb_N; 1.
DR Pfam; PF00364; Biotin_lipoyl; 1.
DR Pfam; PF02786; CPSase_L_D2; 1.
DR Pfam; PF02626; CT_A_B; 1.
DR Pfam; PF02682; CT_C_D; 1.
DR SMART; SM00796; AHS1; 1.
DR SMART; SM00797; AHS2; 1.
DR SMART; SM00878; Biotin_carb_C; 1.
DR SUPFAM; SSF50891; Cyclophilin-like; 2.
DR SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR SUPFAM; SSF160467; PH0987 N-terminal domain-like; 1.
DR SUPFAM; SSF52440; PreATP-grasp domain; 1.
DR SUPFAM; SSF51246; Rudiment single hybrid motif; 1.
DR SUPFAM; SSF51230; Single hybrid motif; 1.
DR PROSITE; PS50975; ATP_GRASP; 1.
DR PROSITE; PS50979; BC; 1.
DR PROSITE; PS00188; BIOTIN; 1.
DR PROSITE; PS50968; BIOTINYL_LIPOYL; 1.
DR PROSITE; PS00867; CPSASE_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00409}; Biotin {ECO:0000256|ARBA:ARBA00023267};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00409}; Reference proteome {ECO:0000313|Proteomes:UP000030980}.
FT DOMAIN 1..444
FT /note="Biotin carboxylation"
FT /evidence="ECO:0000259|PROSITE:PS50979"
FT DOMAIN 120..317
FT /note="ATP-grasp"
FT /evidence="ECO:0000259|PROSITE:PS50975"
FT DOMAIN 1127..1204
FT /note="Lipoyl-binding"
FT /evidence="ECO:0000259|PROSITE:PS50968"
SQ SEQUENCE 1211 AA; 131014 MW; 55C9456C6DF7D47D CRC64;
MFDTVLIANR GEIAVRAIRT LKRLGVKSVA VYSDADRNAQ HVRDADLAIA LGGDKPADSY
LRVDKILAAA AETGAQAIYP GYGFLSESAE FAEACAAAGI AFVGPTPAQI REFGLKHRAR
ELAAEAGVPM APGTGLLSSL EDALAAAERI GYPVMLKTTA GGGGIGLTRC ADAEALASAY
ESVKRMGEQF FSDAGVFLER FVDQARHVEV QIFGDGLGRV VALGERDCSL QRRNQKVVEE
TPAPNLPQAT RERLHAAAVQ LGSSVNYRSA GTVEFIYDAA RDDVYFLEVN TRLQVEHPVT
ERVTGLDLIE CMLRVAAGDA LDWDALGQAP RGAAMEVRLY AEDPLKNFQP SPGALTDVHF
PAGVRVDGWV STGSEVSAFY DPMIAKLIVH GTSREEALQK LRAALAETRL HGIASNLDYL
RQVVADERFA EGRVWTRLLD SFQYTASVIE VLEPGTYSSV QDFPGRLGYW DIGVPPSGPM
DDYAFRLANR IVGNHTSAAG LEFTLQGPTL KFHCDALIAL TGADCPATLD DAPVAYWEPV
SVRAGQVLKL GRAASGCRTY LAVRNGLDVP LYLGSRSTFA LGQFGGHAGR TLRPADMLAI
SQPALPACTT PAPVAPPQAA HASLIPSYGS TWDIGVLYGP HGAPDFFTPE AIEEFFAAEW
EVHYNSNRLG VRLSGPKPSW TRADGGEAGL HPSNVHDCEY AIGSINFTGD FPVILTKDGP
SLGGFVCPVT IAKAELWKVG QVKPGDRLRF HPISFQQAQA LEQAQLGSIE ALAAISAVSL
PAPALQPGST VSATVLAELP ASAGRPQVVY RQAGDAYLLL EYGDNVLDLA LRLRVHLLME
ALKAANIDGL AELAPGVRSL QLRYDSRVLH QRTLLDHLLR LEETLGDVSN LKVPTRIVHL
PMAFEDSATL GAVTRYRETV RAEAPWLPNN VDFLQRINDL DSRERVKDIL YGASYLILGL
GDVYLDAPCA VPLDPRHRLL SSKYNPARTY TAEGTVGIGG MYMCIYGMDS PGGYQLVGRT
LPIWNKYLKN AQFERGEPWL LKFFDQVRFY EVSEEELTAF REAFREGRAQ IRIEQGEFDF
AEYQRFLVDN AESIAAFQQR QKAAFAAEVQ LWRDDDPAAA QPLASAVEDD GDLNGHLVSA
EMSGSVWKVL VQPGQRVEAG TPLLVVEAMK MELAVIAPVA GIVKSVRCQP GKAVTPGDAL
LLLEPESDEA A
//
