ID A0A0B4BL45_9RHOB Unreviewed; 981 AA.
AC A0A0B4BL45;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE SubName: Full=Sarcosine oxidase subunit alpha {ECO:0000313|EMBL:KIC13814.1};
GN ORFNames=RA20_22315 {ECO:0000313|EMBL:KIC13814.1};
OS Leisingera sp. ANG-Vp.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Leisingera.
OX NCBI_TaxID=1577896 {ECO:0000313|EMBL:KIC13814.1, ECO:0000313|Proteomes:UP000031177};
RN [1] {ECO:0000313|Proteomes:UP000031177}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ANG-Vp {ECO:0000313|Proteomes:UP000031177};
RX PubMed=25755651; DOI=10.3389/fmicb.2015.00123;
RA Collins A.J., Fullmer M.S., Gogarten J.P., Nyholm S.V.;
RT "Comparative genomics of Roseobacter clade bacteria isolated from the
RT accessory nidamental gland of Euprymna scolopes.";
RL Front. Microbiol. 6:123-123(2015).
CC -!- SIMILARITY: Belongs to the GcvT family.
CC {ECO:0000256|ARBA:ARBA00008609}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KIC13814.1}.
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DR EMBL; JWLD01000086; KIC13814.1; -; Genomic_DNA.
DR RefSeq; WP_039134157.1; NZ_JWLD01000086.1.
DR AlphaFoldDB; A0A0B4BL45; -.
DR STRING; 1577896.RA20_22315; -.
DR OrthoDB; 5287468at2; -.
DR Proteomes; UP000031177; Unassembled WGS sequence.
DR GO; GO:0008115; F:sarcosine oxidase activity; IEA:InterPro.
DR GO; GO:0046653; P:tetrahydrofolate metabolic process; IEA:InterPro.
DR Gene3D; 3.10.20.440; 2Fe-2S iron-sulphur cluster binding domain, sarcosine oxidase, alpha subunit, N-terminal domain; 1.
DR Gene3D; 1.10.10.1100; BFD-like [2Fe-2S]-binding domain; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR042204; 2Fe-2S-bd_N.
DR InterPro; IPR041854; BFD-like_2Fe2S-bd_dom_sf.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR028896; GCST/YgfZ/DmdA.
DR InterPro; IPR013977; GCV_T_C.
DR InterPro; IPR006222; GCV_T_N.
DR InterPro; IPR029043; GcvT/YgfZ_C.
DR InterPro; IPR006277; Sarcosine_oxidase_asu.
DR InterPro; IPR041117; SoxA_A3.
DR InterPro; IPR027266; TrmE/GcvT_dom1.
DR NCBIfam; TIGR01372; soxA; 1.
DR PANTHER; PTHR43757; AMINOMETHYLTRANSFERASE; 1.
DR PANTHER; PTHR43757:SF2; AMINOMETHYLTRANSFERASE, MITOCHONDRIAL; 1.
DR Pfam; PF12831; FAD_oxidored; 1.
DR Pfam; PF13510; Fer2_4; 1.
DR Pfam; PF01571; GCV_T; 1.
DR Pfam; PF08669; GCV_T_C; 1.
DR Pfam; PF17806; SO_alpha_A3; 1.
DR PIRSF; PIRSF037980; SoxA; 1.
DR PRINTS; PR00368; FADPNR.
DR PRINTS; PR00469; PNDRDTASEII.
DR SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF103025; Folate-binding domain; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 498..583
FT /note="SoxA A3"
FT /evidence="ECO:0000259|Pfam:PF17806"
FT DOMAIN 600..860
FT /note="Aminomethyltransferase folate-binding"
FT /evidence="ECO:0000259|Pfam:PF01571"
FT DOMAIN 887..973
FT /note="Glycine cleavage T-protein C-terminal barrel"
FT /evidence="ECO:0000259|Pfam:PF08669"
SQ SEQUENCE 981 AA; 105991 MW; B849C0FEC004362C CRC64;
MRLPGKGLNQ GAKPITFGFN GRHMMGLEGD TLASALLAND VHLMGRSFKY HRPRGVLTAG
SEEPNALVTV GTGGEQDPNI RATQQELFEG LEARSQNCWP SVERDVMAVN DLAAPFFGAG
FYYKTFMWPA AFWEKVYEPM IRNAAGLGAL SGEADRDTYE KAFAFCDVLV IGSGPAGLMA
ALTAGRAGAD VILAEEDSRM GGRLLAEREE IGGKPGHEWA AEVLAELEAM DNVRLMTRTA
ITGAYDQGTY GALERVSHHL PRRHSLKGSH LPRECFWRIA AKHAVLAAGA IERPVAFRNN
DRPGIMMAGA VRAYLNRWGV APGERVTLFA NNDQAHRTAR DLHEAGVHIA AVIDSRHDAP
VDGPYQVIKG AQVCGSAGRQ RIESITVRSV KGEEKIQTDC LAMSGGWNPS VHLTCHLNSR
PQWNREALAF VPTEGAVPGM VTAGACNGTF STAGALREGA EAAGKVLEAL GLKSAAADLP
DAEDDPYRIA ALWAVPGKGR AWLDFQNDVT VKDVKQAAVE NFRSVEHMKR YTTQGMATDQ
GKNSNVAALA VLADATGRTI PETGTTTFRP PFVPVSLGAM GAGATDEGFK PQRFLTSHGE
SDNRGAHQLE VGLWYRAAYF PKPGETNWRQ SCDREVTLVR KAVGICDVST LGKIDIQGAD
AGKFLDFLYT NTFSTLKVGK VRYGLMLRED GFVMDDGTTA RLGENHYVMT TTTAAAGQVM
AHMEFVSQAL YPEWDVRFTS VTEQWAQFAV AGPKSQELLN GLLDEEVNGE TWPFMGCGEA
TVLGVKGRLF RISFSGEHAY EVAVPARYGE ALFRELLKRA EAMGGGAYGM EALNVLRIEK
GLITHAEING TVTAFDLGLQ GMMSKKKAFL GQAMSTREGL MAEDRMRMVG LKPVGAAKEI
TAGAHLFTPG DPVERIYDQG YVTSAGYSPT LGHPIGLAFL KEGPDRIGET VRLVDHMRGV
DTLCEVVSPV FFDPEGGRAR G
//
