ID A0A0B4FBV4_9RHOB Unreviewed; 745 AA.
AC A0A0B4FBV4;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Adenylate cyclase {ECO:0000313|EMBL:KID08655.1};
GN ORFNames=GC1_16175 {ECO:0000313|EMBL:KID08655.1};
OS Leisingera sp. ANG1.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Leisingera.
OX NCBI_TaxID=1002340 {ECO:0000313|EMBL:KID08655.1, ECO:0000313|Proteomes:UP000031201};
RN [1] {ECO:0000313|EMBL:KID08655.1, ECO:0000313|Proteomes:UP000031201}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ANG1 {ECO:0000313|EMBL:KID08655.1,
RC ECO:0000313|Proteomes:UP000031201};
RX PubMed=21551313; DOI=10.1128/JB.05139-11;
RA Collins A.J., Nyholm S.V.;
RT "Draft genome of Phaeobacter gallaeciensis ANG1, a dominant member of the
RT accessory nidamental gland of Euprymna scolopes.";
RL J. Bacteriol. 193:3397-3398(2011).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KID08655.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AFCF02000008; KID08655.1; -; Genomic_DNA.
DR RefSeq; WP_019294954.1; NZ_AFCF02000008.1.
DR AlphaFoldDB; A0A0B4FBV4; -.
DR STRING; 1002340.GC1_16175; -.
DR eggNOG; COG0457; Bacteria.
DR eggNOG; COG2114; Bacteria.
DR eggNOG; COG5616; Bacteria.
DR OrthoDB; 54411at2; -.
DR Proteomes; UP000031201; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd07302; CHD; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR Gene3D; 3.40.50.10070; TolB, N-terminal domain; 1.
DR InterPro; IPR001054; A/G_cyclase.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR004155; PBS_lyase_HEAT.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR Pfam; PF00211; Guanylate_cyc; 1.
DR Pfam; PF13646; HEAT_2; 1.
DR Pfam; PF14559; TPR_19; 1.
DR SMART; SM00567; EZ_HEAT; 2.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
DR PROSITE; PS50005; TPR; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 192..211
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 11..126
FT /note="Guanylate cyclase"
FT /evidence="ECO:0000259|PROSITE:PS50125"
FT REPEAT 504..537
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ SEQUENCE 745 AA; 78967 MW; B769A4700C866F17 CRC64;
MKSPSNRRLA AILAADVAGY SRLTAADEEG TVAALRAIRS EVVEPLTEQH GGRIANTAGD
SFLIEFRSAV DALRAALSIQ DRLQARNAGV AADRAILLRI GLNVGDVISN GGDILGDGVN
VAARLEALAE PGGITASQAA VSYARKSIAA DYIPMGPQKV KNIPEPVEAY RVQKAGQAPR
PASGSKALRS RLAAWAGLLA AAAAVAVLWI APWQPNPDQA VAARMAFPLP DLPSIAVLPL
ADTTGDSGNA MLADGFSEDL ITDLSRISGL FVISGNSSFA YQDQQISPAQ FAEELGVRYV
VDGSLRRTGA AFRATVRLTD TASGQLVWAE RFDGPLEDVF ALQDRIALAI AQALGLSLDA
EERSGIEQQD TATIAARKAF QQGWELYARF NEQDNLAAIP HFEQAVVLDP GYGRAWAVLA
MAHLRPHILH HWRGYTPATG QTHIGQFYKH LREAVRHDTP LRHVIRAMVL LNLPDWEGVY
GGSRGTIEAR QEAAKAIALQ PSDPEAHLTM GWALIAAGEP EQGLAFVRAA MRLDPKHPSH
YALFEAAALF AMDDLLQAAD VLQAELDRNP HASELMPVAA SVLALQGDLR AAREMVERWH
SGGSTASLPA AVQDYFFILR WTGASQHLNR RLSDGLRLAA LPPGTTVASL RAELSLSDAS
TQRQAARALG LFGAAAAPAV PELTALLDSP SAFVRKEAAN ALGSIGAAAE PALAALDSLA
GTGLAGKRAA LAAERIRSSL AEKDL
//
