ID   A0A0B4H176_METMF        Unreviewed;       944 AA.
AC   A0A0B4H176;
DT   04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT   04-MAR-2015, sequence version 1.
DT   27-MAR-2024, entry version 41.
DE   SubName: Full=Bassianolide synthetase {ECO:0000313|EMBL:KID83501.1};
DE   Flags: Fragment;
GN   ORFNames=MAJ_11310 {ECO:0000313|EMBL:KID83501.1};
OS   Metarhizium majus (strain ARSEF 297).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Clavicipitaceae; Metarhizium;
OC   Metarhizium majus.
OX   NCBI_TaxID=1276143 {ECO:0000313|EMBL:KID83501.1, ECO:0000313|Proteomes:UP000031176};
RN   [1] {ECO:0000313|EMBL:KID83501.1, ECO:0000313|Proteomes:UP000031176}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ARSEF 297 {ECO:0000313|EMBL:KID83501.1,
RC   ECO:0000313|Proteomes:UP000031176};
RX   PubMed=25368161; DOI=10.1073/pnas.1412662111;
RA   Hu X., Xiao G., Zheng P., Shang Y., Su Y., Zhang X., Liu X., Zhan S.,
RA   St Leger R.J., Wang C.;
RT   "Trajectory and genomic determinants of fungal-pathogen speciation and host
RT   adaptation.";
RL   Proc. Natl. Acad. Sci. U.S.A. 111:16796-16801(2014).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KID83501.1}.
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DR   EMBL; AZNE01000452; KID83501.1; -; Genomic_DNA.
DR   RefSeq; XP_014571721.1; XM_014716235.1.
DR   AlphaFoldDB; A0A0B4H176; -.
DR   HOGENOM; CLU_000022_2_12_1; -.
DR   OrthoDB; 2301216at2759; -.
DR   Proteomes; UP000031176; Unassembled WGS sequence.
DR   GO; GO:0044249; P:cellular biosynthetic process; IEA:UniProt.
DR   CDD; cd05918; A_NRPS_SidN3_like; 1.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 1.10.1200.10; ACP-like; 1.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR   Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 1.
DR   InterPro; IPR010071; AA_adenyl_domain.
DR   InterPro; IPR036736; ACP-like_sf.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   InterPro; IPR009081; PP-bd_ACP.
DR   InterPro; IPR006162; Ppantetheine_attach_site.
DR   NCBIfam; TIGR01733; AA-adenyl-dom; 1.
DR   PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR   PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF00550; PP-binding; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   SUPFAM; SSF47336; ACP-like; 1.
DR   SUPFAM; SSF52777; CoA-dependent acyltransferases; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
DR   PROSITE; PS50075; CARRIER; 1.
DR   PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE   4: Predicted;
KW   Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000031176}.
FT   DOMAIN          803..879
FT                   /note="Carrier"
FT                   /evidence="ECO:0000259|PROSITE:PS50075"
FT   REGION          909..944
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KID83501.1"
SQ   SEQUENCE   944 AA;  103456 MW;  B78115E30E6FA426 CRC64;
     MVQRGEGSVR FWQHHFDGLD ASAFPTVTSS TRAPRQDGLL EHEIIHMTWQ AQQKWSNVAI
     CRAALAVLLA RYTHAPEALF GIVVTHLDPD SKNQRAKPAQ AVVPTRVLCA PHQSCSHLLQ
     HVTAHDATVS QLDRAGLDDI RNAGEYASAA CGFQTVLEVV TIQYALQASS NELHHRGIST
     SDAFNLCTDR ALFLECQMAD DSAFIRARYD QSLIDARQMT RFLGQLGCLI KTFLGSGADV
     PIGQLQPPTQ EDQAEIHDWN SAELESSDVC VHDVIAERSA SRPGSTAVFA WDGEWTYEEL
     NNLSSRLAAH IQSLGLNHEQ TVPICFEKSK WVVVGILAVL KAGLAFTLIE PSHPPARIAQ
     ICQQTSATIA LVSKMQYNTL QNLVSHCVIV DDELSQSLSA YQDGFISVAK PQNLAYIIFT
     SGSTGDPKGC MIDHRGFASC ALKYAPELHI SSKSRSLQFA SYAFGACLIE IVATLMQGGC
     VCIPSEEDRM NNITDFINSA GVTWALLTPS FIGAIRPENI PRLQTLVLGG EALSAEIRDT
     WASQVQLLCG YGQSETSSIC SVARIDPGMA DPSNIGRATG ARLWITDPDN PDQLAPIGCI
     GELVVESPGV ARGYIVPPPQ TKSPFIAGTP SWHPTSRYID RFSFYRTGDL VRYKSDGTIV
     YLGRRDLQVK IRGQRVDIGD VETHLRQQLP NDVVAVVEAV QRPSTSHNTI LVAFLVGLNQ
     NGEDNTVSAT RASILEPSVA RNITAKLQQL IPQYGIPSYY ILLKRVPTTA TGKTDRRKLR
     SIGAELLDEM TQNTTSKEET PTDSPISRED TLRQLWFRNL NIDPKSHIQA ANFFDLGGDS
     IAAIKMANMA RSAGIELSVA DIIRYPDLSN LVSKVSVQLC LDLDGIEPIA NRSLTLGTGD
     CSPLPLCAAH DKAKPPPPKH EPRRNFYKRL WGRRSKETPN ELDK
//