ID A0A0B4H8N7_METMF Unreviewed; 777 AA.
AC A0A0B4H8N7;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
DE Flags: Fragment;
GN ORFNames=MAJ_11190 {ECO:0000313|EMBL:KID86141.1};
OS Metarhizium majus (strain ARSEF 297).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Clavicipitaceae; Metarhizium;
OC Metarhizium majus.
OX NCBI_TaxID=1276143 {ECO:0000313|EMBL:KID86141.1, ECO:0000313|Proteomes:UP000031176};
RN [1] {ECO:0000313|EMBL:KID86141.1, ECO:0000313|Proteomes:UP000031176}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ARSEF 297 {ECO:0000313|EMBL:KID86141.1,
RC ECO:0000313|Proteomes:UP000031176};
RX PubMed=25368161; DOI=10.1073/pnas.1412662111;
RA Hu X., Xiao G., Zheng P., Shang Y., Su Y., Zhang X., Liu X., Zhan S.,
RA St Leger R.J., Wang C.;
RT "Trajectory and genomic determinants of fungal-pathogen speciation and host
RT adaptation.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:16796-16801(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KID86141.1}.
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DR EMBL; AZNE01000360; KID86141.1; -; Genomic_DNA.
DR RefSeq; XP_014571842.1; XM_014716356.1.
DR AlphaFoldDB; A0A0B4H8N7; -.
DR HOGENOM; CLU_005513_5_0_1; -.
DR OrthoDB; 2619595at2759; -.
DR Proteomes; UP000031176; Unassembled WGS sequence.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR040976; Pkinase_fungal.
DR InterPro; IPR008266; Tyr_kinase_AS.
DR PANTHER; PTHR38248:SF2; FUNK1 11; 1.
DR PANTHER; PTHR38248; FUNK1 6; 1.
DR Pfam; PF17667; Pkinase_fungal; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS00109; PROTEIN_KINASE_TYR; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Kinase {ECO:0000313|EMBL:KID86141.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000031176};
KW Transferase {ECO:0000313|EMBL:KID86141.1}.
FT DOMAIN 270..679
FT /note="Fungal-type protein kinase"
FT /evidence="ECO:0000259|Pfam:PF17667"
FT REGION 511..548
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 526..540
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KID86141.1"
SQ SEQUENCE 777 AA; 87325 MW; 7910B1D7B0BE505D CRC64;
MTDQLRSDII KNNPIKDNLD DFRTLFASTC QERGLECSPD ALASLDRDDL QNVTIDLILA
LQRLRISRLL LSAAGSKTVL SDLFELGSAA ASADFDFDRV RPLLKSALAS KLDDADIWDQ
VYHAVTEAKS TPPPQPIASS LQQTPWQRNT SSFANSSEYR RDVDMVLKEE LGPLYVGVPG
FCEKFLGNVP DLASASEAVF KKCIMGDSPL FRSGWTKWPS DANQDGVLSW FADLTETLAR
FAEPRTIPRR RRPLAQPNKP IQGSTGERKL DVGFVDDPEA GKESKCHWSH ILIPGELKSN
PTADIALKAW LDLGRYTREV LTAQDTRRFV LGFTLCGSLI RLWRFDRIGG VASEQFDVNT
DGLQFVKIIL AFLWMNEEDL GFDPTVIVSS GKKFVDIERN GHLERLIIDK TLLRVSCIAG
RATTCWKAHR EGSSEILVIK DSWQYKERKE EGDLLQLATM RGVSHIARYY HHEVVKIRGI
DDDVRHNVRK GLDVTKAANY RPGRSGFASL SDVTEVKRRG HSDGTGLKRS SSQTFPPSKR
ARSESPIKAS VDVLPDRIHR RGVISDYGKP IYTASTPVVL LNALADCIEG HKSLRKMAGL
LHRDISMNNL MIDEDSTNPS RRSFLIDLDL ATEESRAEAS GSRGKTGTRA FMAIGALLGE
QHLFMHDLES FFWVLFWVCI HYDGPHKEKR VARFDKWNFV DTEELAGTKL GIIAEEDMFC
KTTSDWFTEH YKGMAPCINK LRKVVFPAGG RWKVETEGLY ESMRKILLEA RNEVSAK
//
