ID   A0A0B4HXP2_METMF        Unreviewed;       376 AA.
AC   A0A0B4HXP2;
DT   04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT   04-MAR-2015, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Alpha/beta hydrolase fold-1 {ECO:0000313|EMBL:KIE00039.1};
DE   Flags: Fragment;
GN   ORFNames=MAJ_04095 {ECO:0000313|EMBL:KIE00039.1};
OS   Metarhizium majus (strain ARSEF 297).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Clavicipitaceae; Metarhizium;
OC   Metarhizium majus.
OX   NCBI_TaxID=1276143 {ECO:0000313|EMBL:KIE00039.1, ECO:0000313|Proteomes:UP000031176};
RN   [1] {ECO:0000313|EMBL:KIE00039.1, ECO:0000313|Proteomes:UP000031176}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ARSEF 297 {ECO:0000313|EMBL:KIE00039.1,
RC   ECO:0000313|Proteomes:UP000031176};
RX   PubMed=25368161; DOI=10.1073/pnas.1412662111;
RA   Hu X., Xiao G., Zheng P., Shang Y., Su Y., Zhang X., Liu X., Zhan S.,
RA   St Leger R.J., Wang C.;
RT   "Trajectory and genomic determinants of fungal-pathogen speciation and host
RT   adaptation.";
RL   Proc. Natl. Acad. Sci. U.S.A. 111:16796-16801(2014).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KIE00039.1}.
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DR   EMBL; AZNE01000014; KIE00039.1; -; Genomic_DNA.
DR   RefSeq; XP_014578916.1; XM_014723430.1.
DR   AlphaFoldDB; A0A0B4HXP2; -.
DR   HOGENOM; CLU_020336_11_1_1; -.
DR   OrthoDB; 2403795at2759; -.
DR   Proteomes; UP000031176; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR000073; AB_hydrolase_1.
DR   InterPro; IPR022742; Hydrolase_4.
DR   PANTHER; PTHR43194; HYDROLASE ALPHA/BETA FOLD FAMILY; 1.
DR   PANTHER; PTHR43194:SF2; PEROXISOMAL MEMBRANE PROTEIN LPX1; 1.
DR   Pfam; PF12146; Hydrolase_4; 1.
DR   PRINTS; PR00111; ABHYDROLASE.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:KIE00039.1};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000031176};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        166..186
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          94..210
FT                   /note="Serine aminopeptidase S33"
FT                   /evidence="ECO:0000259|Pfam:PF12146"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KIE00039.1"
SQ   SEQUENCE   376 AA;  41107 MW;  CF97AD2D61152467 CRC64;
     MDTLLRWPDI PHPAVVATTA AVATASLIVV AKATLWPRRR SVLQSPLKTV LPRASREELS
     ELVYLPDAFP GARDVETPYG TIRVYEFGPE DGDKVLLVHG ISTSCITLGR IAHALVERGC
     RVMLFDLFGR GFTDGVGDIP HDTRLYTTQI LLVLASSRLS WTGTSGFRLI GYSLGGGIVI
     PFANAFPHMV SSLVLLAPAG LIDAASFGAV SRFIFSSGFI PERILAVLTG QRLQRPIASS
     RAARSKAAGV LAVAEAENLA GEKTPLEERV LDYVRWMVHN HEGFVPAFMS CIRYAPLTEQ
     HEEWKGLAKR ERGTTAVIFA ETDELISADD YARDGLPLVG GEGHVFWRVV PGSHDFVMTH
     VAAIMKELDE FWDMKA
//