ID A0A0B4I2X3_METMF Unreviewed; 300 AA.
AC A0A0B4I2X3;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=DNA replication complex GINS protein PSF2 {ECO:0000256|ARBA:ARBA00015139};
DE AltName: Full=DNA replication complex GINS protein psf2 {ECO:0000256|ARBA:ARBA00013969};
DE Flags: Fragment;
GN ORFNames=MAJ_01972 {ECO:0000313|EMBL:KIE02314.1};
OS Metarhizium majus (strain ARSEF 297).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Clavicipitaceae; Metarhizium;
OC Metarhizium majus.
OX NCBI_TaxID=1276143 {ECO:0000313|EMBL:KIE02314.1, ECO:0000313|Proteomes:UP000031176};
RN [1] {ECO:0000313|EMBL:KIE02314.1, ECO:0000313|Proteomes:UP000031176}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ARSEF 297 {ECO:0000313|EMBL:KIE02314.1,
RC ECO:0000313|Proteomes:UP000031176};
RX PubMed=25368161; DOI=10.1073/pnas.1412662111;
RA Hu X., Xiao G., Zheng P., Shang Y., Su Y., Zhang X., Liu X., Zhan S.,
RA St Leger R.J., Wang C.;
RT "Trajectory and genomic determinants of fungal-pathogen speciation and host
RT adaptation.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:16796-16801(2014).
CC -!- FUNCTION: The GINS complex plays an essential role in the initiation of
CC DNA replication. Has a role in chromosome segregation.
CC {ECO:0000256|ARBA:ARBA00025163}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the GINS2/PSF2 family.
CC {ECO:0000256|ARBA:ARBA00010565}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KIE02314.1}.
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DR EMBL; AZNE01000005; KIE02314.1; -; Genomic_DNA.
DR RefSeq; XP_014581307.1; XM_014725821.1.
DR AlphaFoldDB; A0A0B4I2X3; -.
DR HOGENOM; CLU_078274_0_0_1; -.
DR OrthoDB; 5487178at2759; -.
DR Proteomes; UP000031176; Unassembled WGS sequence.
DR GO; GO:0000228; C:nuclear chromosome; IEA:UniProt.
DR GO; GO:0032993; C:protein-DNA complex; IEA:UniProt.
DR GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR GO; GO:0006261; P:DNA-templated DNA replication; IEA:UniProt.
DR CDD; cd11712; GINS_A_psf2; 1.
DR CDD; cd21694; GINS_B_Psf2; 1.
DR Gene3D; 1.20.58.1020; -; 1.
DR Gene3D; 3.40.5.50; -; 1.
DR InterPro; IPR021151; GINS_A.
DR InterPro; IPR036224; GINS_bundle-like_dom_sf.
DR InterPro; IPR007257; GINS_Psf2.
DR PANTHER; PTHR12772; DNA REPLICATION COMPLEX GINS PROTEIN PSF2; 1.
DR PANTHER; PTHR12772:SF0; DNA REPLICATION COMPLEX GINS PROTEIN PSF2; 1.
DR Pfam; PF05916; Sld5; 1.
DR PIRSF; PIRSF028998; GINS_Psf2_subgr; 1.
DR SUPFAM; SSF158573; GINS helical bundle-like; 1.
DR SUPFAM; SSF160059; PriA/YqbF domain; 1.
PE 3: Inferred from homology;
KW Chromosome partition {ECO:0000256|ARBA:ARBA00022829};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000031176}.
FT DOMAIN 101..254
FT /note="GINS subunit"
FT /evidence="ECO:0000259|Pfam:PF05916"
FT REGION 139..158
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 276..300
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KIE02314.1"
SQ SEQUENCE 300 AA; 32566 MW; 1A6882552AE6DFD5 CRC64;
MRHGQGGVKS LIIELNDGTL NEGLSDVNPN SRVLASVRDH TRLSVAVPST MALRLPPGLV
PSEVAFLCEM ELVTVVPRQR LESIHLLAGQ TPQLRPPRRS NLPLWLALLL KKQRRANIVP
PPWMHPDSLR DVIHHETKVD TKGWAPPPPP RSRADSLGNA TRINSLSGKE TILSPPFLPS
CTADAPSGAL PYHWFELAEM LLAHAGDDIA SASEVRSLLR DLQEVRAAKM RSSTAQLESG
VDGVMSLRGV GAMELAESRG FVTGVVEGVR TIGASAEAMR REEEEQGRDD GETSDDDMGL
//
