ID A0A0B4II59_METMF Unreviewed; 691 AA.
AC A0A0B4II59;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Nonsense-mediated mRNA decay protein 1 {ECO:0000313|EMBL:KIE00165.1};
DE Flags: Fragment;
GN ORFNames=MAJ_03822 {ECO:0000313|EMBL:KIE00165.1};
OS Metarhizium majus (strain ARSEF 297).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Clavicipitaceae; Metarhizium;
OC Metarhizium majus.
OX NCBI_TaxID=1276143 {ECO:0000313|EMBL:KIE00165.1, ECO:0000313|Proteomes:UP000031176};
RN [1] {ECO:0000313|EMBL:KIE00165.1, ECO:0000313|Proteomes:UP000031176}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ARSEF 297 {ECO:0000313|EMBL:KIE00165.1,
RC ECO:0000313|Proteomes:UP000031176};
RX PubMed=25368161; DOI=10.1073/pnas.1412662111;
RA Hu X., Xiao G., Zheng P., Shang Y., Su Y., Zhang X., Liu X., Zhan S.,
RA St Leger R.J., Wang C.;
RT "Trajectory and genomic determinants of fungal-pathogen speciation and host
RT adaptation.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:16796-16801(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KIE00165.1}.
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DR EMBL; AZNE01000013; KIE00165.1; -; Genomic_DNA.
DR RefSeq; XP_014579158.1; XM_014723672.1.
DR AlphaFoldDB; A0A0B4II59; -.
DR HOGENOM; CLU_011691_0_0_1; -.
DR OrthoDB; 2689044at2759; -.
DR Proteomes; UP000031176; Unassembled WGS sequence.
DR GO; GO:0004386; F:helicase activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR041679; DNA2/NAM7-like_C.
DR InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR43788:SF19; DNA-BINDING PROTEIN SMUBP-2; 1.
DR PANTHER; PTHR43788; DNA2/NAM7 HELICASE FAMILY MEMBER; 1.
DR Pfam; PF13086; AAA_11; 1.
DR Pfam; PF13087; AAA_12; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022806};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000031176}.
FT DOMAIN 178..433
FT /note="DNA2/NAM7 helicase helicase"
FT /evidence="ECO:0000259|Pfam:PF13086"
FT DOMAIN 456..656
FT /note="DNA2/NAM7 helicase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13087"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KIE00165.1"
SQ SEQUENCE 691 AA; 79631 MW; E42FF089735D8FBA CRC64;
MVSNVKRGGD EYSLVHIPAT RIPNPFETCE AVRDTRIKTF AAYKVDVPRS WTNSEGDHIE
LDLMSEFQIS CRASDLDKIF LEEHEHQLLT IEWDVNSATF EAELDALHFF TEEKRLQNRG
PTLKSQRAFR MILNFHSSWK DFYDLHKDFP QLSNPELRRH AVPDAILRRF KAFNNDHSRA
FNGLKQIPNG LYFVNGCPGS GKTEWNMILA GLIQCSKRRH KKKRNPILFL VDINKAVDDA
ASRYYSLCQE AGVKIRIVRM HGWPLEMRQS AKLHGSRSTT NQDSFAVPDF TNRFLVTAGL
SKQTSVSRDP GIVPTLDQAS WEYFEKNKRD AFLGLQKLLD KMDSGEALST DDWKHLRSHV
SRLYRVVLAR TDFIATTPVA AYGRFSKFFK PDIIFMDEAS HARELTTLIP LAYFTPKAWI
FTGDVKQTQP FVKDAKDREK HSGLRFNPFA AQLRMSTMAR ADHVNAVNSK LLVNKRAFGN
LHRLPSAMFY ESQMRSGYDE ASRYPDGVAY LTIYLQNLNG NRHVDENRII VNMENSNEEK
HRDSYWNPLH HQWVLAQATH LLQDDGFRGL RDREMGGTIM IATPYSTAVK QYHAAVKSWP
ESWQRRTQVL TVDKAQGNEA DVVFLDMVRT TTAGFMDDPK RLNVAITRAR QAEVILMRRT
MAYVPGKKFG RSKYLSQLWD DTLLHKRIVT I
//
