ID A0A0B4XKE2_9GAMM Unreviewed; 345 AA.
AC A0A0B4XKE2;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=lipopolysaccharide heptosyltransferase II {ECO:0000256|ARBA:ARBA00044042};
DE EC=2.4.99.24 {ECO:0000256|ARBA:ARBA00044042};
GN ORFNames=S7S_02250 {ECO:0000313|EMBL:AJD46872.1};
OS Isoalcanivorax pacificus W11-5.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Alcanivoracaceae; Isoalcanivorax.
OX NCBI_TaxID=391936 {ECO:0000313|EMBL:AJD46872.1, ECO:0000313|Proteomes:UP000006764};
RN [1] {ECO:0000313|EMBL:AJD46872.1, ECO:0000313|Proteomes:UP000006764}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=W11-5 {ECO:0000313|EMBL:AJD46872.1,
RC ECO:0000313|Proteomes:UP000006764};
RX PubMed=23209202; DOI=10.1128/JB.01845-12;
RA Lai Q., Shao Z.;
RT "Genome sequence of an alkane-degrading bacterium, Alcanivorax pacificus
RT type strain W11-5, isolated from deep sea sediment.";
RL J. Bacteriol. 194:6936-6936(2012).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ADP-L-glycero-beta-D-manno-heptose + an L-alpha-D-Hep-(1->5)-
CC [alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A = ADP + an L-alpha-D-Hep-
CC (1->3)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid
CC A + H(+); Xref=Rhea:RHEA:74071, ChEBI:CHEBI:15378, ChEBI:CHEBI:61506,
CC ChEBI:CHEBI:193068, ChEBI:CHEBI:193069, ChEBI:CHEBI:456216;
CC EC=2.4.99.24; Evidence={ECO:0000256|ARBA:ARBA00043830};
CC -!- SIMILARITY: Belongs to the glycosyltransferase 9 family.
CC {ECO:0000256|ARBA:ARBA00043995}.
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DR EMBL; CP004387; AJD46872.1; -; Genomic_DNA.
DR RefSeq; WP_008739386.1; NZ_CP004387.1.
DR AlphaFoldDB; A0A0B4XKE2; -.
DR STRING; 391936.S7S_02250; -.
DR KEGG; apac:S7S_02250; -.
DR HOGENOM; CLU_038371_7_0_6; -.
DR OrthoDB; 9797795at2; -.
DR Proteomes; UP000006764; Chromosome.
DR GO; GO:0016757; F:glycosyltransferase activity; IEA:InterPro.
DR GO; GO:0009103; P:lipopolysaccharide biosynthetic process; IEA:InterPro.
DR CDD; cd03789; GT9_LPS_heptosyltransferase; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR InterPro; IPR002201; Glyco_trans_9.
DR InterPro; IPR011910; RfaF.
DR NCBIfam; TIGR02195; heptsyl_trn_II; 1.
DR PANTHER; PTHR30160:SF7; ADP-HEPTOSE--LPS HEPTOSYLTRANSFERASE 2; 1.
DR PANTHER; PTHR30160; TETRAACYLDISACCHARIDE 4'-KINASE-RELATED; 1.
DR Pfam; PF01075; Glyco_transf_9; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE 3: Inferred from homology;
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW Reference proteome {ECO:0000313|Proteomes:UP000006764};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:AJD46872.1}.
SQ SEQUENCE 345 AA; 38276 MW; A1929B532E800BC0 CRC64;
MSEAPRRILV IGPSWVGDMV MAQTLFSALR AQHPDCLIDV LAPDWCRALL ARMPEVRQAL
SLPFGHGDLR LRERRELGRG LAGEYDQAIV LPNSFKSALL PFWARIPVRT GWRGEMRYGL
LNDVRTLDKQ RYPLMVQRFV ALAHPAGAPV PALADIAPPH LRVDTSNADR TLQNMGLNQA
LPILALCPGA EFGPSKRWPE QYYAEVARHQ LEQGWQVWIF GSPKDREVAE LIRDAIPEKL
RWRLHLLAGE TALPEAVDLL ALANAVISND SGLMHIAAAL HRPLVAVYGS TSPDFTPPLH
GQVETVRLGL DCSPCFKREC PLGHLNCLRQ LGPDQVIAAL GRVRA
//
