ID A0A0B4XZX1_9PROT Unreviewed; 650 AA.
AC A0A0B4XZX1;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Acetoacetyl-CoA synthetase {ECO:0000313|EMBL:AJD51963.1};
DE EC=6.2.1.16 {ECO:0000313|EMBL:AJD51963.1};
GN ORFNames=TH3_09235 {ECO:0000313|EMBL:AJD51963.1};
OS Thalassospira xiamenensis M-5 = DSM 17429.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Thalassospiraceae; Thalassospira.
OX NCBI_TaxID=1123366 {ECO:0000313|EMBL:AJD51963.1, ECO:0000313|Proteomes:UP000007127};
RN [1] {ECO:0000313|EMBL:AJD51963.1, ECO:0000313|Proteomes:UP000007127}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M-5 {ECO:0000313|EMBL:AJD51963.1,
RC ECO:0000313|Proteomes:UP000007127};
RX PubMed=23209216; DOI=10.1128/JB.01904-12;
RA Lai Q., Shao Z.;
RT "Genome sequence of Thalassospira xiamenensis type strain M-5.";
RL J. Bacteriol. 194:6957-6957(2012).
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DR EMBL; CP004388; AJD51963.1; -; Genomic_DNA.
DR RefSeq; WP_007092147.1; NZ_FTON01000003.1.
DR AlphaFoldDB; A0A0B4XZX1; -.
DR STRING; 1123366.TH3_09235; -.
DR GeneID; 31927518; -.
DR KEGG; txi:TH3_09235; -.
DR eggNOG; COG0365; Bacteria.
DR HOGENOM; CLU_000022_3_3_5; -.
DR Proteomes; UP000007127; Chromosome.
DR GO; GO:0030729; F:acetoacetate-CoA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR CDD; cd05943; AACS; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR005914; Acac_CoA_synth.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR01217; ac_ac_CoA_syn; 1.
DR PANTHER; PTHR42921; ACETOACETYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR42921:SF1; ACETOACETYL-COA SYNTHETASE; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:AJD51963.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 37..92
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 99..471
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 542..612
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 650 AA; 72473 MW; 9FD762F3F44A498D CRC64;
MSDLLWQPSP ARVENANVTR FRNWVNEKHS LKLDSFHALY DWSVASKEDF WPAIIDYVGL
KAESWGDSVL VDGYKMPGAK FFPNARLNFS ENLLVRDDDT DALVFWGEDK VKTRISWCDL
NIAVSKFSQA LRAEGIKKGD RVCGYMPNMV ETVIAMLGTA AIGATWSSAS PDFGVQGVVD
RFGQIEPKLM ITVDGYHYNG KSHDIREKVR DVVDRITTIQ KVVIVKYAFD GTNTTGIRNG
VSYDNFLAPF SPEKIVFEQV EFNHPLYVMF SSGTTGKPKC IVHGAGGTLL KQVSEHVLHC
DVVPGDRVFY FTTCGWMMWN WLMGGLAAGA TLLLYDGSPF YPSGNILFDY ADAEGMTLFG
TSAKYIDALA KAELKPRETH DLSTVRAMTS TGSPLAPESF DYVYRDIKSD IHLASISGGT
DILGCFVLAC PVLPVKRGII QTRALGLAVD VFDDDGKSIR NQKGELVCTA PFPSMPIGFW
NDPDGARYKE AYFNRFDNIW CHGDYVELDD DGGMVIYGRS DATLNPGGVR IGTAEIYRQV
EKLPEIQESI VIGQEWDNDV RVILFVVLRE KYQLDELLID RIRKQIRNNC TPRHVPAKII
AVADIPRTKS GKITELAVRD VVHGRPVKNQ EALANPTALE LFSNLPELRS
//
