ID A0A0B4Y4N0_9PROT Unreviewed; 377 AA.
AC A0A0B4Y4N0;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=NAD-binding 6-phosphogluconate dehydrogenase {ECO:0000313|EMBL:AJD53567.1};
GN ORFNames=TH3_17325 {ECO:0000313|EMBL:AJD53567.1};
OS Thalassospira xiamenensis M-5 = DSM 17429.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Thalassospiraceae; Thalassospira.
OX NCBI_TaxID=1123366 {ECO:0000313|EMBL:AJD53567.1, ECO:0000313|Proteomes:UP000007127};
RN [1] {ECO:0000313|EMBL:AJD53567.1, ECO:0000313|Proteomes:UP000007127}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M-5 {ECO:0000313|EMBL:AJD53567.1,
RC ECO:0000313|Proteomes:UP000007127};
RX PubMed=23209216; DOI=10.1128/JB.01904-12;
RA Lai Q., Shao Z.;
RT "Genome sequence of Thalassospira xiamenensis type strain M-5.";
RL J. Bacteriol. 194:6957-6957(2012).
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DR EMBL; CP004388; AJD53567.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0B4Y4N0; -.
DR STRING; 1123366.TH3_17325; -.
DR KEGG; txi:TH3_17325; -.
DR eggNOG; COG2084; Bacteria.
DR HOGENOM; CLU_035117_1_1_5; -.
DR Proteomes; UP000007127; Chromosome.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:UniProt.
DR GO; GO:0016054; P:organic acid catabolic process; IEA:UniProt.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006115; 6PGDH_NADP-bd.
DR InterPro; IPR029154; HIBADH-like_NADP-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR22981:SF7; 3-HYDROXYISOBUTYRATE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR22981; 3-HYDROXYISOBUTYRATE DEHYDROGENASE-RELATED; 1.
DR Pfam; PF14833; NAD_binding_11; 1.
DR Pfam; PF03446; NAD_binding_2; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 88..245
FT /note="6-phosphogluconate dehydrogenase NADP-binding"
FT /evidence="ECO:0000259|Pfam:PF03446"
FT DOMAIN 248..365
FT /note="3-hydroxyisobutyrate dehydrogenase-like NAD-binding"
FT /evidence="ECO:0000259|Pfam:PF14833"
SQ SEQUENCE 377 AA; 39171 MW; 5FBA37195B831EB7 CRC64;
MTMVVDVSGG VPDHLIRPHV LLFRQQHVPA IDLEFAGYPP ESSGAKSKNH IGPHRCRDGK
ARALTGCARL SESKEANIVS NPETGTTGVV GLGNMGLGMA RTLLRDGFSV IGFDVSMECQ
AKAAASGVTI VAGLSELFEA CPTIILSLPT ANHVRKVLGG DEGLGGRDID PRLVIDTTTS
EPDVTRELDA VLRMQGHILI DAPVSGGPAG ANSGNLTMMV GGGDADVARA MPVLNSLGGK
ITHVGPVGAG HAVKIVNNML VASHLLTMSE AVRLGNAAGV TTENLIAALN AGSGRSAISE
VNYPKWVMNG AFDSGFTMGL MRKDVRLAMA LAKDKKVAMP VSELAGQIWA ASEELLSDNA
DFNRITECDP THAGAKS
//
