ID A0A0B5D6K8_9ACTN Unreviewed; 495 AA.
AC A0A0B5D6K8;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=DNA helicase {ECO:0000313|EMBL:AJE38679.1};
GN ORFNames=BJY54_006892 {ECO:0000313|EMBL:MBB4796188.1}, CP978_00370
GN {ECO:0000313|EMBL:QEV37251.1}, SNOD_00030
GN {ECO:0000313|EMBL:AJE38679.1};
OS Streptomyces nodosus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=40318 {ECO:0000313|EMBL:AJE38679.1, ECO:0000313|Proteomes:UP000031526};
RN [1] {ECO:0000313|Proteomes:UP000031526}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 14899 {ECO:0000313|Proteomes:UP000031526};
RA Sweeney P., Stephens N., Murphy C., Caffrey P.;
RT "Sequence of the Streptomyces nodosus genome.";
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AJE38679.1, ECO:0000313|Proteomes:UP000031526}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 14899 {ECO:0000313|EMBL:AJE38679.1,
RC ECO:0000313|Proteomes:UP000031526};
RX PubMed=26497174;
RA Sweeney P., Murphy C.D., Caffrey P.;
RT "Exploiting the genome sequence of Streptomyces nodosus for enhanced
RT antibiotic production.";
RL Appl. Microbiol. Biotechnol. 100:1285-1295(2016).
RN [3] {ECO:0000313|EMBL:QEV37251.1, ECO:0000313|Proteomes:UP000325763}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 14899 {ECO:0000313|EMBL:QEV37251.1,
RC ECO:0000313|Proteomes:UP000325763};
RA Lee N., Cho B.-K.;
RT "Streptomyces genome completion.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:MBB4796188.1, ECO:0000313|Proteomes:UP000544950}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 40109 {ECO:0000313|EMBL:MBB4796188.1,
RC ECO:0000313|Proteomes:UP000544950};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (AUG-2020) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP009313; AJE38679.1; -; Genomic_DNA.
DR EMBL; JACHMR010000002; MBB4796188.1; -; Genomic_DNA.
DR EMBL; CP023747; QEV37251.1; -; Genomic_DNA.
DR RefSeq; WP_043436622.1; NZ_JACHMR010000002.1.
DR STRING; 40318.SNOD_00030; -.
DR KEGG; snq:CP978_00370; -.
DR HOGENOM; CLU_023291_2_0_11; -.
DR OrthoDB; 5318045at2; -.
DR Proteomes; UP000031526; Chromosome.
DR Proteomes; UP000325763; Chromosome.
DR Proteomes; UP000544950; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR PANTHER; PTHR11070:SF30; F-BOX DNA HELICASE 1; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF13245; AAA_19; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000031526}.
FT DOMAIN 3..278
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT BINDING 24..31
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 495 AA; 54235 MW; 1A080103E03DC6C6 CRC64;
MNPTEEQAAA ADAFHAGDHL SLQAGAGTGK TTTLALLART TKRRGRYLAY NRTIAQDAAE
RFPRTVQCKT AHALAYAAVG HRYTRRLNAP RRPAWQTGHA LGITKTIRIG DREVSQKALS
NTVLRTVAHF CHTADDTITR HHVPHLRGLE HQTLHAELTA HILPFARKAW TDIQDPDDGC
VRFDHDHYLK IWALTRPRIH ADFLLLDEAQ DTNPVVEQIF LNQRSHAQLV MVGDSAQAIY
HWRGAKDVMT GFNGTQLALS QSFRFGPRLA QEANRWLHIA GAPIRLTGTP AVPTELGPVA
CPDAVLCRTN AGAMAQVITL MADGRRVALA GGGDGLRALA LAARDLKEGR RTSHPELLLF
PGWGELQDYA AHDPAGRDLQ PLVDLVDKHG TETILNAVAG LAPEQHAEVT VSTAHKAKGR
EWACVRIADD FAPPKNSSHK DDNGCTIPEP IDDSDARLAY VAVTRTRWRL DMDGLSWIDH
HPDGNPAASK RASPT
//
