ID A0A0B5DK60_9ACTN Unreviewed; 383 AA.
AC A0A0B5DK60;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=O methyltransferase {ECO:0000313|EMBL:AJE43569.1};
DE SubName: Full=SAM-dependent methyltransferase {ECO:0000313|EMBL:MBB4795049.1};
GN ORFNames=BJY54_005661 {ECO:0000313|EMBL:MBB4795049.1}, CP978_29040
GN {ECO:0000313|EMBL:QEV42072.1}, SNOD_28765
GN {ECO:0000313|EMBL:AJE43569.1};
OS Streptomyces nodosus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=40318 {ECO:0000313|EMBL:AJE43569.1, ECO:0000313|Proteomes:UP000031526};
RN [1] {ECO:0000313|Proteomes:UP000031526}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 14899 {ECO:0000313|Proteomes:UP000031526};
RA Sweeney P., Stephens N., Murphy C., Caffrey P.;
RT "Sequence of the Streptomyces nodosus genome.";
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AJE43569.1, ECO:0000313|Proteomes:UP000031526}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 14899 {ECO:0000313|EMBL:AJE43569.1,
RC ECO:0000313|Proteomes:UP000031526};
RX PubMed=26497174;
RA Sweeney P., Murphy C.D., Caffrey P.;
RT "Exploiting the genome sequence of Streptomyces nodosus for enhanced
RT antibiotic production.";
RL Appl. Microbiol. Biotechnol. 100:1285-1295(2016).
RN [3] {ECO:0000313|EMBL:QEV42072.1, ECO:0000313|Proteomes:UP000325763}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 14899 {ECO:0000313|EMBL:QEV42072.1,
RC ECO:0000313|Proteomes:UP000325763};
RA Lee N., Cho B.-K.;
RT "Streptomyces genome completion.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:MBB4795049.1, ECO:0000313|Proteomes:UP000544950}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 40109 {ECO:0000313|EMBL:MBB4795049.1,
RC ECO:0000313|Proteomes:UP000544950};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (AUG-2020) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP009313; AJE43569.1; -; Genomic_DNA.
DR EMBL; JACHMR010000001; MBB4795049.1; -; Genomic_DNA.
DR EMBL; CP023747; QEV42072.1; -; Genomic_DNA.
DR RefSeq; WP_043445705.1; NZ_JACHMR010000001.1.
DR STRING; 40318.SNOD_28765; -.
DR KEGG; snq:CP978_29040; -.
DR HOGENOM; CLU_762703_0_0_11; -.
DR OrthoDB; 582216at2; -.
DR Proteomes; UP000031526; Chromosome.
DR Proteomes; UP000325763; Chromosome.
DR Proteomes; UP000544950; Unassembled WGS sequence.
DR GO; GO:0008171; F:O-methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR016461; COMT-like.
DR InterPro; IPR001077; O_MeTrfase_dom.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR43712:SF2; O-METHYLTRANSFERASE CICE; 1.
DR PANTHER; PTHR43712; PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED; 1.
DR Pfam; PF00891; Methyltransf_2; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51683; SAM_OMT_II; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000313|EMBL:AJE43569.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000031526};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000313|EMBL:AJE43569.1}.
FT DOMAIN 214..363
FT /note="O-methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00891"
SQ SEQUENCE 383 AA; 42418 MW; 1761FB7A557075A7 CRC64;
MTPGVTTPAD FETDDTPAPE LNIRPLVDNA LLPDWRGAGK VVHSAHRIYE HLISLWAPGV
IEAAHDLGVF AELSTGPKTS DQLATACDAE QRAMRVLMDG LYAYDIVDRI PADAGPALYR
MSEEMHECLL PGGLFSLVGK IEYDRQLAWH SWRNLADAVR RDNRDETGSL QLNQITEHNY
ESLVRGINFW APPIVEALRG GFETLEWPTD RPASVLDIGC GTGLYSQLLL RAFPGWRATG
LEAPNIAPIA RAQAERLGVA DRFDVQVRDF WTESWGSDHD LLVFVNIFHL QTPESAQELL
RRSKEALSKD GLVCIADHLV TDEKDAKSIQ DRFAMLFAAS MLATGGGDAF LLDDYDRWLA
SAGLRRVAVL DTPMHRILLA GHA
//
