ID A0A0B5DMQ8_9ACTN Unreviewed; 726 AA.
AC A0A0B5DMQ8;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=ATP-dependent DNA helicase {ECO:0000313|EMBL:AJE42590.1};
GN ORFNames=SNOD_23025 {ECO:0000313|EMBL:AJE42590.1};
OS Streptomyces nodosus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=40318 {ECO:0000313|EMBL:AJE42590.1, ECO:0000313|Proteomes:UP000031526};
RN [1] {ECO:0000313|Proteomes:UP000031526}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 14899 {ECO:0000313|Proteomes:UP000031526};
RA Sweeney P., Stephens N., Murphy C., Caffrey P.;
RT "Sequence of the Streptomyces nodosus genome.";
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AJE42590.1, ECO:0000313|Proteomes:UP000031526}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 14899 {ECO:0000313|EMBL:AJE42590.1,
RC ECO:0000313|Proteomes:UP000031526};
RX PubMed=26497174;
RA Sweeney P., Murphy C.D., Caffrey P.;
RT "Exploiting the genome sequence of Streptomyces nodosus for enhanced
RT antibiotic production.";
RL Appl. Microbiol. Biotechnol. 100:1285-1295(2016).
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DR EMBL; CP009313; AJE42590.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0B5DMQ8; -.
DR STRING; 40318.SNOD_23025; -.
DR HOGENOM; CLU_010312_3_1_11; -.
DR Proteomes; UP000031526; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR PANTHER; PTHR11070:SF45; ATP-DEPENDENT DNA HELICASE UVRD2; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000031526}.
FT DOMAIN 161..581
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT BINDING 182..189
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 726 AA; 79104 MW; 946F1170726F9256 CRC64;
MDALRGDTET SVADALAQGD TPMQARLERD ILVAERSGLL AALNAVDGSL CFGRIDLASG
QSHHIGRIGL RTEDAERTPV LIDWRADVAR PFYLATGHTP MGLRRRRHIG TDGRRVTSLH
DEILDLSDHE RTGHEDPSGD AALLSSLTSA RTGRMSDIVG TIQADQDRII RAPHRGVLVV
EGGPGTGKTA VALHRAAYLL YEHRELLARR AVLIVGPNPA FLGYIGEVLP SLGETGVLLA
TVGELFPGVR ASEADTPWAA AVKGRAEMAE VLAAVVADRQ ALPDPVIAVE HDREVLMLDD
GLVKVARERT RAAGLPHNAA REHFEGHVLN TLTDMVAERI GTDPYDGSNL LDASDITQIR
DELADNPEVW SAIDQLWPRL TPERLVADFL AEPDGYLSEE DADAVRRPVT LAWTTADVPL
LDEAAELLGD DERTVRARAE RERETQVAYA QGVLDVSYAS RTYEFEDKDD DDSEVLSAHD
IIDAERFAER QEEADHRSAA ERAAGDRTWA FGHIIVDEAQ ELSPMAWRLL MRRSPTRAMT
LVGDPAQTAE AGGVGSWSGI LAPYVEDRWE HTRLGVNYRT PSEIMDLAAA VVRAENPDFE
PPSSVRSTGV RPWVRQVDDD LPGAVHRAVA ELTPAEGRLA VIAPRELHRA LAARLDEVEA
GAEPDLTRTV VLLDPRQAKG LEFDSVLVVE PGKYGTSDVY VALTRATQRL GVLHTGKLPK
ALAPHA
//
