ID A0A0B5DUG3_9ACTN Unreviewed; 479 AA.
AC A0A0B5DUG3;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Cro/Cl family transcriptional regulator {ECO:0000313|EMBL:AJE43792.1};
DE SubName: Full=Transcriptional regulator/transcriptional regulator with XRE-family HTH domain {ECO:0000313|EMBL:MBB4795328.1};
DE SubName: Full=XRE family transcriptional regulator {ECO:0000313|EMBL:QEV42299.1};
GN ORFNames=BJY54_005940 {ECO:0000313|EMBL:MBB4795328.1}, CP978_30460
GN {ECO:0000313|EMBL:QEV42299.1}, SNOD_30155
GN {ECO:0000313|EMBL:AJE43792.1};
OS Streptomyces nodosus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=40318 {ECO:0000313|EMBL:AJE43792.1, ECO:0000313|Proteomes:UP000031526};
RN [1] {ECO:0000313|Proteomes:UP000031526}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 14899 {ECO:0000313|Proteomes:UP000031526};
RA Sweeney P., Stephens N., Murphy C., Caffrey P.;
RT "Sequence of the Streptomyces nodosus genome.";
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AJE43792.1, ECO:0000313|Proteomes:UP000031526}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 14899 {ECO:0000313|EMBL:AJE43792.1,
RC ECO:0000313|Proteomes:UP000031526};
RX PubMed=26497174;
RA Sweeney P., Murphy C.D., Caffrey P.;
RT "Exploiting the genome sequence of Streptomyces nodosus for enhanced
RT antibiotic production.";
RL Appl. Microbiol. Biotechnol. 100:1285-1295(2016).
RN [3] {ECO:0000313|EMBL:QEV42299.1, ECO:0000313|Proteomes:UP000325763}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 14899 {ECO:0000313|EMBL:QEV42299.1,
RC ECO:0000313|Proteomes:UP000325763};
RA Lee N., Cho B.-K.;
RT "Streptomyces genome completion.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:MBB4795328.1, ECO:0000313|Proteomes:UP000544950}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 40109 {ECO:0000313|EMBL:MBB4795328.1,
RC ECO:0000313|Proteomes:UP000544950};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (AUG-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the short-chain fatty acyl-CoA assimilation
CC regulator (ScfR) family. {ECO:0000256|ARBA:ARBA00007227}.
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DR EMBL; CP009313; AJE43792.1; -; Genomic_DNA.
DR EMBL; JACHMR010000001; MBB4795328.1; -; Genomic_DNA.
DR EMBL; CP023747; QEV42299.1; -; Genomic_DNA.
DR RefSeq; WP_043446213.1; NZ_JACHMR010000001.1.
DR STRING; 40318.SNOD_30155; -.
DR KEGG; snq:CP978_30460; -.
DR HOGENOM; CLU_046383_0_0_11; -.
DR OrthoDB; 9810578at2; -.
DR Proteomes; UP000031526; Chromosome.
DR Proteomes; UP000325763; Chromosome.
DR Proteomes; UP000544950; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00093; HTH_XRE; 1.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR001387; Cro/C1-type_HTH.
DR InterPro; IPR026281; HTH_RamB.
DR InterPro; IPR010359; IrrE_HExxH.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR018653; ScfR_C.
DR PANTHER; PTHR46797; HTH-TYPE TRANSCRIPTIONAL REGULATOR; 1.
DR PANTHER; PTHR46797:SF23; HTH-TYPE TRANSCRIPTIONAL REGULATOR PRPR; 1.
DR Pfam; PF13560; HTH_31; 1.
DR Pfam; PF06114; Peptidase_M78; 1.
DR Pfam; PF09856; ScfRs; 1.
DR PIRSF; PIRSF019251; Rv0465c; 1.
DR SMART; SM00530; HTH_XRE; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR PROSITE; PS50943; HTH_CROC1; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000031526};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 16..70
FT /note="HTH cro/C1-type"
FT /evidence="ECO:0000259|PROSITE:PS50943"
FT REGION 452..479
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 479 AA; 52555 MW; 5D032B28826CF9CF CRC64;
MAGRTAGRKV YAHAKLRRLR RERGMNQVDM ARALAISTSY ANQIEQSQRP LTAPILLRIA
EVFGVDAEFF SEAEEDRLSA DLRAALADEA CGVPLPATEE IAEAARDHPE VARALVALHR
RYREAAEQAA ALASPGTGPL LPPGEPHDEV RDFFYAHHNH FEPLDTEAEH AVEALELRPG
RAADPLTARL AGRHGVRVVQ AAQSRSGDAR RFDPDTGLLF LSPWLSDGQR AFQLATQLAL
LEHGPLLGQL ADSATELTSP ESAALARIGL ANYFAGALLM PYTAFHTAAE DVRYDIELLS
ARFGVGFETV CHRLSTLQRT GRRGVPFSFL RVDRAGNISK RQSATDFHFS RLGGTCPLWT
VYEAFSAPGR ILTQVAEMPD GKRYFWIART ITRGGFGHQA PRAEFALALG CELRHAHRLV
YAQGIALDDP RAATPIGLGC RICERRDCAQ RARPPAGGRL SIDPDRRTYV PYPVETHGP
//
